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  • 1
    Electronic Resource
    Electronic Resource
    Novel adaptive directly water-cooled monochromator crystal for high heat load wiggler beamlines : Proceedings of the 5th international conference on synchrotron radiation instrumentation (1995)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 66 (1995), S. 2217-2219 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The performance of large area directly cooled monochromator crystals at high-power wiggler beamlines is degraded by the heat load from insertion devices and by the pressure of the cooling agent. Based on the experience gained with directly water-cooled crystals at HASYLAB, a new adaptive crystal with remotely controlled crystal bender was built. A characterization of the first new Si(111) crystal under different heat load conditions up to 850 W is presented. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1145711
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  • 2
    Electronic Resource
    Electronic Resource
    A NOTE ON NONAFFINE SOLUTIONS OF TERM STRUCTURE EQUATIONS WITH APPLICATIONS TO POWER EXCHANGES (2005)
    350 Main Street , Malden , MA 02148 , USA , and 9600 Garsington Road , Oxford OX4 2DQ , UK . : Blackwell Publishing, Inc.
    Mathematical finance 15 (2005), S. 0 
    Details
    ISSN: 1467-9965
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mathematics , Economics
    Notes: A method based on transformations of well-known solutions of term structure equations is presented in order to incorporate Martin Barlow's spot price model for electricity into a model for future prices on electricity. The setting for the evolution of term structures is chosen in the spirit of Da Prato and Zabczyk.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0960-1627.2005.00216.x
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  • 3
    Electronic Resource
    Electronic Resource
    Runaway electron distributions and their stability with respect to the anomalous Doppler resonance (1988)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 31 (1988), S. 2221-2227 
    Details
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The stability of nonrelativistic runaway electron distributions with respect to the anomalous Doppler resonance is examined in a range of parameters of interest to tokamaks, i.e., for Y≡ωpe/Ωce≤2 and for Ohmic electric fields ε≡E/Ec≤0.1. Distribution functions are calculated numerically within a region up to 35ve (thermal velocities) using a finite-element 2-D Fokker–Planck code. Alternatively, an analytic approximation for the runaway distribution function is used, valid beyond the critical velocity vc(approximately-equal-to)ve(Ec/E)1/2. Stability thresholds in (ω,k(parallel)) space are then determined. For example, for Y=1 and ε=0.1, and providing that the runaway tail extends at least to 30ve, unstable waves exist having ω≤0.6Ωce and k(parallel)≤0.03Ωce/ve.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.866623
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  • 4
    Electronic Resource
    Electronic Resource
    Predicting the Strongest Domain-Domain Contact in Interacting Protein Pairs (2006)
    Berkeley, Calif. : Berkeley Electronic Press (now: De Gruyter)
    Statistical applications in genetics and molecular biology 5.2006, 1, art5 
    Details
    ISSN: 1544-6115
    Source: Berkeley Electronic Press Academic Journals
    Topics: Biology
    Notes: Experiments to determine the complete 3-dimensional structures of protein complexes are difficult to perform and only a limited range of such structures are available.In contrast, large-scale screening experiments have identified thousands of pairwise interactions between proteins, but such experiments do not produce explicit structural information.In addition, the data produced by these high through-put experiments contain large numbers of false positive results, and can be biased against detection of certain types of interaction.Several methods exist that analyse such pairwise interaction data in terms of the constituent domains within proteins, scoring pairs of domain superfamilies according to their propensity to interact.These scores can be used to predict the strongest domain-domain contact (the contact with the largest surface area) between interacting proteins for which the domain-level structures of the individual proteins are known.We test this predictive approach on a set of pairwise protein interactions taken from the Protein Quaternary Structure (PQS) database for which the true domain-domain contacts are known.While the overall prediction success rate across the whole test data set is poor, we shown how interactions in the test data set for which the training data are not informative can be automatically excluded from the prediction process, giving improved prediction success rates at the expense of restricted coverage of the test data.
    Type of Medium: Electronic Resource
    URL: http://www.bepress.com/sagmb/vol5/iss1/art5
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  • 5
    Electronic Resource
    Electronic Resource
    Ultrastructure and opsin immunocytochemistry of the pineal complex of the larval Arctic charr Salvelinus alpinus: A comparison with the retina (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of pineal research 10 (1991), S. 0 
    Details
    ISSN: 1600-079X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: The fine structure and opsin immunocytochemistry of the pineal and parapineal organs of the salmonid fish Salvelinus alpinus, the landlocked Arctic charr, were studied and compared with the retina in various developmental stages, from prehatching to two-month-old. For opsin immunocytochemistry two polyclonal antibovine rhodopsin and the monoclonal antichicken opsin antibodies OS-2 (detecting blue and green pigments) and OS-1 (detecting green and red pigments) were used.Histologically, the pineal organ consists of nervous tissue like that of the retina. It is composed of photoreceptor pinealocytes, which formed axon terminals containing synaptic ribbons, on the dendrites and perikarya of secondary pineal neurons. Already in prehatching embryos, both the pineal and retinal photoreceptors display well-developed outer segments and form synaptic terminals. The distal part of the pineal organ differentiates earlier than its proximal stalk. The differentiation of the retina starts centrally, but the caudal and dorsal retinae are differentiated earlier than the rostral and ventral ones. At the end of the larval period, the lateral retina is still undifferentiated.In all stages studied, (rhod)opsin immunoreactivity was found in the outer segments of the pineal organ and rod-type retinal photoreceptors, a finding speaking in favour of the presence of the opsin of a rhodopsin/porphyropsin. Cone-type retinal photoreceptors identified morphologically in the pre- and posthatching stages were opsinimmunonegative with the four primary antisera used. This result suggests that in the charr the opsins of cone visual pigments differ in their chemical nature from those of rhodopsin/porphyropsin. The parapineal organ was opsin immunonegative. Using the monoclonal antibody OS-2 opsin immunoreactivity was also detected in inner segments, perikarya, and pedicles of rod-type photoreceptors of both retina and pineal organ of embryos and 1- to 4-day-old larvae. This may indicate a high level of opsin gene expression during photoreceptor growth around hatching. The well-developed pineal organ and its opsin content are discussed in connection with the photonegative behaviour of the larval charr.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-079X.1991.tb00816.x
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  • 6
    Electronic Resource
    Electronic Resource
    Cholecystokinin Inhibits Food Intake at a Peripheral Extragastric Site (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 713 (1994), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1994.tb44118.x
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  • 7
    Electronic Resource
    Electronic Resource
    Development of a mouse-specific cDNA set for microarray gene expression analysis: differential gene expression in melanocyte lineage samples of the neural crest (1999)
    [s.l.] : Nature America, Inc.
    Nature genetics 23 (1999), S. 78-78 
    Details
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] We are developing sets of mouse cDNAs with low redundancy for use in microarray analysis. The sets are based on sequence information from GenBank and the Washington University/Merck EST sequencing project. Related sequences from the non-redundant GenBank database were compared with mouse EST ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/14414
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  • 8
    Electronic Resource
    Electronic Resource
    Computing protein function (2000)
    [s.l.] : Nature America Inc.
    Nature biotechnology 18 (2000), S. 27-27 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We are more than the sum of our genes. Once genome projects have provided us with the list of an organism's genes, we have to determine how the proteins encoded by those genes cooperate to create and maintain the organism. This is a formidable task for the experimentalist, and even at the rapid ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/71882
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  • 9
    Electronic Resource
    Electronic Resource
    Gene regulatory network growth by duplication (2004)
    [s.l.] : Nature Publishing Group
    Nature genetics 36 (2004), S. 492-496 
    Details
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] We are beginning to elucidate transcriptional regulatory networks on a large scale and to understand some of the structural principles of these networks, but the evolutionary mechanisms that form these networks are still mostly unknown. Here we investigate the role of gene duplication in network ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/ng1340
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  • 10
    Electronic Resource
    Electronic Resource
    Making family trees from gene families (1999)
    [s.l.] : Nature America Inc.
    Nature genetics 21 (1999), S. 66-67 
    Details
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Since the time of Linnaeus, phylogenetic trees have been constructed using similarity of morphological characters to assess the relationships of organisms. The 1960s witnessed the evolution of an alternative (and now, familiar) system that uses the bases in nucleic acids or amino acids in ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/5001
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