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  • 1
    Digitale Medien
    Digitale Medien
    Westerville, Ohio : American Ceramics Society
    Journal of the American Ceramic Society 83 (2000), S. 0 
    ISSN: 1551-2916
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Maschinenbau , Physik
    Notizen: Structure formation in the combustion synthesis of Al2O3–TiC composites from TiO2, Al, and graphite powders was investigated using cylindrical samples and cone-shaped “quenching samples.” It is shown that the phases Ti and Ti3Al exist as intermediates in the combustion synthesis process. Titanium carbide forms in a secondary step through reactions between graphite and liquid Ti or Ti3Al, then nucleates from a liquid mixture of the three phases Ti, Ti3Al, and alumina. The nucleated particles grow in the postcombustion stage. Liquid alumina, containing TiC as a dissolved phase, solidifies into corundum grains in the postcombustion stage. Moreover, it is shown that the temperature gradient in the postcombustion stage markedly affects the microstructures of the products. Higher-temperature gradients, typical at the surface of the samples, give rise to the formation of corundum whiskers and TiC agglomerates. In contrast, lower gradients, typical in the center of the samples, lead to the formation of relatively large TiC particles and corundum grains.
    Materialart: Digitale Medien
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  • 2
    Digitale Medien
    Digitale Medien
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 79 (1996), S. 5440-5442 
    ISSN: 1089-7550
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: α″-Fe16N2 single crystal films can be prepared successfully by facing targets sputtering directly onto NaCl(100) substrates in a mixture of argon and nitrogen gases. Both x-ray diffractometer and transmission electron microscope are employed to characterize the crystal structure of the films. The perfect electron diffraction patterns of α″-Fe16N2 single crystal in [1¯11], [011], and [001] directions can be distinctly observed by double tilting. These patterns confirm that the crystal structure of the films corresponds to a body-centered tetragonal (bct) lattice with the parameters of a=b=5.72 A(ring) and c=6.29 A(ring) . The x-ray diffraction patterns show that α″-Fe16N2 epitaxially grows on the NaCl(100) substrate with an orientation relationship α″-Fe16N2(001)(parallel)NaCl(001) and α″-Fe16N2[100](parallel)NaCl[100]. The saturation magnetization of the Fe16N2 films is around 2100−2300 emu/cc, which agrees well with the value reported by Sugita et al.. © 1996 American Institute of Physics.
    Materialart: Digitale Medien
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  • 3
    Digitale Medien
    Digitale Medien
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 78 (1995), S. 2596-2600 
    ISSN: 1089-7550
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Fe-N gradient films were prepared with a facing targets sputtering system. During deposition, the nitrogen pressure increased linearly up to a value, which is called the "ultimate pressure.'' Composition profiles, microstructure, magnetic properties, and corrosion resistance of the films were investigated by various methods. The experimental results indicate that the Fe-N films possess some composition and structural gradients. The Fe concentration decreases from the substrate to the film surface from 100 to 66 at. %. The phases α‘-Fe16N2, γ'-Fe4N, ε-FexN(2〈x≤3) and ζ-Fe2N are present in the gradient films at different depths. Ms under the ultimate nitrogen pressure of 0.05 Pa has a value of 1803 emu/cc which is higher than that of bulk iron, this is attributed to the presence of Fe16N2. Increasing further the ultimate nitrogen pressure, Ms decreases monotonically. The corrosion resistance of the gradient film with higher nitrogen concentration near the surface is good enough for magnetic recording heads. © 1995 American Institute of Physics.
    Materialart: Digitale Medien
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  • 4
    Digitale Medien
    Digitale Medien
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 80 (1996), S. 4776-4778 
    ISSN: 1089-7550
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Direct current resistivity and its temperature dependence for nanostructured NiAl (n-NiAl) was investigated at temperatures from 77 to 300 K. The resistivity of n-NiAl (size 5–6 nm) was higher than that of polycrystalline NiAl and increased with decreasing density. For the n-NiAl with relative density D(approximately-greater-than)70%, the resistivity decreased with decreasing temperature, manifesting metallic behavior. However, its temperature coefficient of resistivity decreased monotonically with decreasing density, and changed sign from positive to negative at densities 68%–70%, below which it displays on nonmetallic behavior. These results can be well interpreted by dominant grain boundary scattering. © 1996 American Institute of Physics.
    Materialart: Digitale Medien
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  • 5
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 68 (2003), S. 0 
    ISSN: 1750-3841
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: : The objective of this project was to treat fresh-cut apple slices with the ethylene inhibitor 1-methylcyclopropene (1-MCP) to retard ethylene-induced deterioration and senescence and to prolong the shelf life of such products. Intact Braeburn and Pacific Rose apples were treated at different times with 1-MCP, cut, and stored at 0 °C. Samples were analyzed initially and then weekly for ethylene, respiration, flesh firmness, tissue color, titratable acidity, and soluble solids content during 5 wk of storage. 1-MCP treatment was effective in reducing ethylene production, respiration, and loss of firmness and color of slices when applied to whole apples directly after harvest. Total sugar and acidity levels were not affected significantly.
    Materialart: Digitale Medien
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  • 6
    ISSN: 1460-9568
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The present study examined temporal changes in activity of large conductance, Ca2+-activated potassium (BKCa) channels in postischemic CA1 pyramidal neurons at 2, 6, 24 and 48 h after reperfusion. These changes in activity and possible cellular mechanisms were examined using the inside–out configuration of patch clamp. The unitary conductance of postischemic BKCa channels increased transiently to 119% of the control at 2 h after reperfusion, and recovered to the control level thereafter. A persistent increase in [Ca2+]i sensitivity of BKCa channels was observed in postischemic CA1 neurons with the maximal sensitivity to [Ca2+]i at 6 h after reperfusion while channel voltage- dependence showed no obvious changes. Kinetic analyses showed that the postischemic enhancement of BKCa channel activity was due to longer open times and shorter closed times as there was no significant changes in opening frequency after ischemia. Glutathione disulphide markedly increased BKCa channel activity in normal CA1 neurons, while reducing glutathione caused a decrease in BKCa channel activity by reducing the sensitivity of this channel to [Ca2+]i in postischemic CA1 neurons. Similar modulatory effects on postischemic BKCa channels were also observed with another redox couple, DTNB and DTT, suggesting an oxidation modulation of BKCa channel function after ischemia. The present results indicate that a persistent enhancement in activity of BKCa channels, probably via oxidation of channels, in postischemic CA1 pyramidal neurons may account for the decrease in neuronal excitability and increase in fAHP after ischemia. The ischemia-induced augmentation in BKCa channel activity may be also associated with the postischemic neuronal injury.
    Materialart: Digitale Medien
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  • 7
    ISSN: 1460-9568
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Dystroglycan is a core component of the dystrophin receptor complex in skeletal muscle which links the extracellular matrix to the muscle cytoskeleton. Dystrophin, dystrophin-related protein (DRP, utrophin) and dystroglycan are present not only in muscles but also in the brain. Dystrophin is expressed in certain neuronal populations while DRP is associated with perivascular astrocytes. To gain insights into the function and molecular interactions of dystroglycan in the brain, we examined the localization of α-and β-dystroglycan at the cellular and subcellular levels in the rat cerebellum. In blood vessels, we find a-dystroglycan associated with the laminin a2-chain-rich parenchymal vascular basement membrane and β-dystroglycan associated with the endfeet of perivascular astrocytes. We also show that a-dystroglycan purified from the brain binds a2-chain-containing laminin-2. These observations suggest a dystroglycan-mediated linkage between DRP in perivascular astrocytic endfeet and laminin-2 in the parenchymal basement membrane similar to that described in skeletal muscle. This linkage of the astrocytic endfeet to the vascular basement membrane is likely to be important for blood vessel formation and stabilization and for maintaining the integrity of the blood-brain barrier. In addition to blood vessel labelling, we show that β-dystroglycan in the rat cerebellum is associated with the surface of Purkinje cell bodies, dendrites and dendritic spines. Dystrophin has previously been localized to the inner surface of the plasma membrane of Purkinje cells and is enriched at postsynaptic sites. Thus, the present results also support the hypothesis that dystrophin interacts with dystroglycan in cerebellar Purkinje neurons.
    Materialart: Digitale Medien
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  • 8
    Digitale Medien
    Digitale Medien
    Melbourne, Australia : Blackwell Publishing Ltd.
    Nephrology 8 (2003), S. 0 
    ISSN: 1440-1797
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: SUMMARY:  Renal replacement therapy is frequently required for critically ill patients with a high risk of bleeding. Conventional heparinization strategies to prevent extracorporeal blood circuit clotting can cause significant haemorrhage in such patients because of systemic anticoagulation. Regional citrate anticoagulation (RCA) is a well-established technique that minimizes this complication by the decalcification of blood in the extracorporeal circuit such that it is incapable of clotting. To date, there are no reports on the use of RCA for sustained low-efficiency dialysis/diafiltration (SLED), a hybrid therapy that involves the use of conventional haemodialysis machinery to deliver lower solute clearances over prolonged periods of time. In preparation for clinical study, an in vitro simulation of SLED was devised (blood substitute flow 250 mL/min, dialysate flow 200 mL/min, predilution haemofiltration 100 mL/min). Blood substitute was decalcified by an infusion of 4% trisodium citrate (TSC) proximally into the extracorporeal blood circuit, with partial restoration of calcium homeostasis from dialysate containing ionized [Ca2+] at 0.9 mmol/L. This simulation was used to establish first the 4% TSC requirement for therapeutic decalcification, and second the associated changes in ionized [Ca2+] and [Mg2+] within the blood substitute from chelation with citrate and subsequent removal of the resulting divalent cation-citrate complex. Serial measurements of blood substitute [Ca2+] from strategic points along the extracorporeal circuit showed therapeutic decalcification was not achieved with 4% TSC infusion rates up to 400 mL/h, and extrapolation of experimental results suggests that 450 mL/h will be required. Under these conditions, ionized [Ca2+] and [Mg2+] in the blood substitute venous return and would be 0.42 and 0.2 mmol/L, respectively, with 0.35 mmol of citrate being returned per minute via the blood substitute venous return. These results were modelled for various changes in SLED operating parameters, and discussed in detail. An appropriate regimen for 4% TSC infusion and divalent cation replacement is proposed for clinical study in the future.
    Materialart: Digitale Medien
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  • 9
    Digitale Medien
    Digitale Medien
    Amsterdam : Elsevier
    Archives of Biochemistry and Biophysics 247 (1986), S. 221-232 
    ISSN: 0003-9861
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie , Chemie und Pharmazie , Physik
    Materialart: Digitale Medien
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  • 10
    Digitale Medien
    Digitale Medien
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Molecular Basis of Disease 1181 (1993), S. 111-121 
    ISSN: 0925-4439
    Schlagwort(e): Hepatic lymphoma ; Phosphocholine ; Phosphoethanolamine ; Phospholipid synthesis ; ^3^1P magnetic resonance spectroscopy
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie , Chemie und Pharmazie , Medizin , Physik
    Materialart: Digitale Medien
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