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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of toxicology 32 (1974), S. 307-311 
    ISSN: 1432-0738
    Keywords: Amphetamine ; Fatal Poisoning ; Thin-Layer Chromatographic Spectrophotofluorometric Determination ; Distribution ; Amphetamin ; Tödliche Vergiftung ; Dünnschichtchromatographische spektrofluorometrische Bestimmung ; Verteilung im Körper
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die anatomisch-pathologische und chemisch-toxikologische Untersuchung einer ungewöhnlichen Intoxikation mit Amphetamin wird beschrieben. Die quantitative Analyse von Amphetamin erfolgte in verschiedenen Organen und Körperflüssigkeiten durch Dünnschichtchromatographie und Spektrophotofluorometrie nach Kupplung von Amphetamin mit 4-Chloro-7-nitrobenzo-2,1,3-oxadiazol (NBD-Cl). Es wurden sehr hohe Konzentrationen in Harn und Blut und nur geringe Mengen Amphetamin in Magen- und Dünndarminhalt festgestellt. Die Ergebnisse sprechen für eine intravenöse Amphetamin-Injektion in tödlich wirkender Menge.
    Notes: Abstract A pathological report and toxicological examination of an uncommon case of fatal amphetamine poisoning are presented. Amphetamine was quantified in different tissues by thin-layer chromatography and spectrophotofluorometry after fluorigenic labeling of amphetamine with 4-chloro-7-nitrobenzo-2,1,3-oxadiazole (NBD-Cl). The distribution study of amphetamine showed an extremely high concentration of amphetamine in urine and blood; fairly small amounts were found in the contents of the stomach and small intestine. These figures could indicate that the subject had taken amphetamine over a long period and that his death was probably caused by intravenous injection of amphetamine.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 18 (1977), S. 110-114 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Stomach, small intestine contents, “blood, liver, kidney and urine of a 28-years old man, were analyzed for residues of Endosulfan (6, 7, 8, 9, 10, 10-hexachloro-1, 5, 5a, 6, 9, 9a-hexahydro-6, 9-methano-2, 4, 3-benzo(e)dioxathiepin 3-oxide). The analysis results showed the presence of high concentrations of the two endosulfan isomers in all samples. Since also alcohol was present in all the tissues analyzed, it was concluded that the victim died of a combined endosulfan-alcohol poisoning. No other drugs were found.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 71 (1972), S. 139-144 
    ISSN: 1437-1596
    Keywords: Lyell-Syndrome ; Toxic Epidermal Necrolysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Bericht über einen Fall von Lyell-Syndrom (Epidermolysis toxica acuta). Fünfjähriges Mädchen entwickelte 2 Tage nach Aufnahme von 5mal 100 mg Monophenylbutazon (in Westdeutschland nicht im Handel) ein Exanthem aus kleinen roten Flecken. 2 Tage später erschienen klare Blasen, und schließlich ließ sich fast am ganzen Körper die Haut in großen Fetzen ablösen. Tod bei Hypothermie und zunehmender Bewuß tseinstrübung 18 Tage nach Beginn der Erscheinungen. Die Sektion ergab u. a. makroskopisch Bronchopneumonie, Mediastinalemphysern, Hirndruck, Stauungsorgane; mikroskopisch leichte Leberverfettung, toxische Schwellung der Milzkeimzentren, Entspeicherung der Nebennierenrinde; bakteriologisch: Pseudomonas aeruginosa. Die Eltern beschuldigten Ärzte und Apotheker der falschen Behandlung. Fälle dieser Art können irrtümlich als Verbrennung angesehen oder als therapeutische Unglücksfälle mit allen möglichen rechtlichen Konsequenzen gedeutet werden.
    Notes: Summary The authors describe toxic epidermal necrolysis and report on the clinical observation and post mortem findings in a 5 year old girl, treated with monophenylbutazone. The correct diagnosis is important since the changes might otherwise be wrongly ascribed to burning. The diagnosis also raises the question of a therapeutic mishap and, in turn, the possibility of a claim for compensation.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 88 (1982), S. 39-48 
    ISSN: 1437-1596
    Keywords: Ethanol level, in the testicle ; Alcohol test, postmortem in the testicle ; Äthanolnachweis, im Hodengewebe ; Alkoholbestimmung, postmortem im Hodengewebe
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Nach langjährigen Untersuchungen wird an 633 statistisch ausgewerteten Fällen die Korrelation zwischen Alkohol im Hodengewebe und im Blut mit r=0.92, ermittelt. Auf die Einflüsse von Fäulnis, Wasserliegezeit oder posttraumatischem Blutverlust wird hingewiesen. Akuter Blutverlust brachte keine nennenswerte Veränderung. Bei chronischem Blutverlust ist nach Kaufmann et al. [25] mit einer Beeinträchtigung zu rechnen. Insgesamt ist die Methode geeignet, eine Alkoholbeeinflussung bei männlichen Leichen bis zu etwa 72h Liegezeit zu überprüfen, wenn keine Blutwerte ermittelt oder sonstige Körperflüssigkeiten bzw. Organe mehr gesichert werden können.
    Notes: Summary This study emphasizes the value of the presence of ethanol in the testicle. It proves particularly useful in cases where blood and urine are no more present in the body. In 633 cases where blood or urine were still available, a highly positive correlation between the blood alcohol and the amount of alcohol present in the testicle could be demonstrated, thus confirming the research carried out in the Department of Legal Medicine as far back as 1943. An attempt is further made to assess the possible influence of such factors as putrefaction, submersion or post-traumatic anemia on this correlation.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 63 (1968), S. 127-128 
    ISSN: 1437-1596
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Summary The author describes research carried out in Belgium on the diatom-test as proof of drowning. The lungs of bodies recovered from the water were positive in 26 cases out of 29, the figures varying from hundreds to thousands in each lung. The 3 other cases were entirely negative. The lungs of 17 bodies, where death resulted from other causes than drowning, were taken as controls. 13 cases were negative. In 4 cases, 2 of which were late exhumations of bodies recovered from wooden coffins, a few diatoms were present. The liver of 5 drowning-cases was likewise subjected to chemical digestion. The result was invariably positive, the figures varying from a few diatoms to hundreds of them. The liver of twelve control-cases was likewise examined. Eleven were negative. In one case, again an exhumation, a few diatoms were detected. The investigation is being pursued.
    Type of Medium: Electronic Resource
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