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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 109 (1987), S. 7597-7602 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 55 (1983), S. 2260-2266 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 8 (1986), S. 217-220 
    ISSN: 1279-8517
    Keywords: Ear-cough reflex ; Arnold's nerve
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Une étude clinique de 500 malades a mis en évidence un réflexe d'Arnold (réflexe auriculaire de toux) chez 4,2% d'entre eux. Ce réflexe était bilatéral chez 2,8% des patients. Il a pu être déclenché au niveau de la paroi antérieure du conduit auditif externe chez 2% d'entre eux, remettant en question la distribution classique du nerf, d'Arnold au niveau de la paroi postérieure du conduit auditif externe. Le nerf d'Arnold peut véhiculer d'autres réflexes: auriculo-palatin, auriculo-lacrymal, auriculo-cardiaque et le réflexe du vomissement; mais ils sont moins marqués et surtout moins fréquents que le réflexe auriculaire de toux.
    Notes: Summary A clinical survey of 500 patients revealed 4.2% incidence of Arnold's ear-cough reflex. The reflex was bilateral in 2.8% of the patients. It was also elicitable from the anterior meatal wall in 2% of the patients, thus questioning the classically taught distribution of Arnold's nerve. Arnold's nerve also mediates the auriculo-palatal auriculo-lacrimal, auriculo-cardiac and the ear-vomiting reflexes; but these are less apparent and not so commonly encountered.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Electrical engineering 66 (1983), S. 163-170 
    ISSN: 1432-0487
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Description / Table of Contents: Contents A review on experimental investigations of magnetically caused shaft-potentials in turbogenerators indicates that the rules for segmentation of stator cores fail to explain the dominant components of voltage. The paper deals with the generation of shaft-voltages caused by overlapped joints, the magnetic effect of which depends on saturation. Rules for the generation of shaft voltages are derived and a method for numerical computing is described. Finally the generation of shaft-potentials due to differing width of joints is discussed.
    Notes: Übersicht Ein überblick des Befundes experimenteller Untersuchungen der magnetisch verursachten Wellenspannungen von Turbogeneratoren macht deutlich, daß sich ihre Entstehung nicht anhand der bekannten Teilbarkeitsregeln erklären läßt. Die Arbeit behandelt die Entstehung von Wellenspannungen infolge überlappter Stoßfugen, deren magnetische Wirkung in jeder Halbwelle des Jochflusses erst mit einsetzender Sättigung des Eisens eintritt. Nach der Ableitung der hierfür geltenden Teilbarkeitsregeln wird eine numerische Berechnung der Wellenspannungen angegeben. In der abschließenden Deutung des experimentellen Befundes wird die Wirkung ungleicher Stoßfugen betrachtet.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Electrical engineering 73 (1990), S. 253-260 
    ISSN: 1432-0487
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Description / Table of Contents: Contents A method is developed for the calculation of harmonic fields in reluctance machines with segmental-rotor. The influences of rotor slotting caused by squirrel-cage damper and segmentation can be determined by directand quadrature-axis permeance harmonics resulting in modulation of the stator-excited fields. The wider slots at the quadrature axis lead to a dense spectrum of air-gap permeance waves. In order to find out the harmonic fields due to saturation and eccentricity the influence of segmentation will be neglected.
    Notes: Übersicht Es wird ein Verfahren zur Berechnung der Oberfelder in Reluktanzmaschinen mit segmentiertem Läufer angegeben. Die Einflüsse der Nutung des Läufers infolge des Dämpferkäfigs und der Segmentierung lassen sich durch Leitwertswellen für die Längs- und Querachse erfassen, die eine Modulation der vom Ständer erregten Felder bewirken. Wegen der breiteren Nuten in der Pollücke tritt ein dichtes Spektrum von Leitwertswellen auf. Zur Ermittlung der Sättigungs- und Exzentrizitätsfelder wird der Einfluß der Segmentierung vernachlässigt.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Electrical engineering 73 (1990), S. 293-298 
    ISSN: 1432-0487
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Description / Table of Contents: Contents A survey is made on the basis of the field calculation performed in part 1 of the numbers of pole-pairs and frequencies of the harmonic magnetic fields in order to find out the most important radial force waves. The resulting audio frequency spectrum is compared to experimental investigations of a 22 kW-reluctance motor. The unequal slot pitch of the squirrel-cage damper results in a dense frequency spectrum which, in connection with the mechanical natural frequencies, causes high noise levels.
    Notes: Übersicht Zur Ermittlung der wichtigsten Radialkraftwellen wird anhand der in Teil 1 ausgeführten Feldberechnung eine Übersicht über die Polpaarzahlen und Frequenzen der Oberfelder erstellt. Das sich hieraus ergebende Tonfrequenzspektrum wird mit experimentellen Untersuchungen an einem 22kW-Reluktanzmotor verglichen. Die ungleichmäßige Nutteilung des Dämpferkäfigs ergibt ein dichtes Frequenzspektrum, das in Verbindung mit mechanischen Eigenfrequenzen zu hohen Geräuschpegeln führt.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 154 (1990), S. 414-416 
    ISSN: 1432-072X
    Keywords: Cyanobacterium ; Ammonium assimilation ; Glutamine auxotrophy ; Transformation ; MSX-resistance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Glutamine auxotrophic (Gln -) and l-methionine d,l-sulfoximine (MSX) resistant (MSX r) mutants of N. muscorum were isolated and characterized for nitrogen nutrition, nitrogenase activity, glutamine synthetase (GS) activity and glutamine amide, α-keto-glutarate amido transferase (GOGAT) activity. The glutamine auxotroph was found to the GOGAT-containing GS-defective, incapable of growth with N2 or NH 4 + but capable of growth with glutamine as nitrogen source, thus, suggesting GS to be the primary enzyme of both ammonia assimilation and glutamine formation in the cyanobacterium. The results of transformation and reversion studies suggests that glutamine auxotrophy is the result of a mutation in the gln A gene and that gln A gene can be transferred from one strain to another by transformation.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1041
    Keywords: nicardipine ; angina pectoris ; haemodynamic ; pharmacokinetics ; radionuclide studies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Pharmacokinetic, haemodynamic and radionuclide studies explored the acute pharmacokinetic and pharmacodynamic actions of nicardipine in patients with coronary heart disease. Nicardipine infusion resulted in dose-related reductions in systolic and diastolic blood pressure and an increased heart rate. Pharmacodynamic activity was evident between 12 and 24 min following 5 and 10 mg i.v. nicardipine but by 3–6 min following the higher doses of 15 and 20 mg; hypotensive activity persisted for up to 2 h. Post-infusion nicardipine concentrations declined biexponentially; however the limited data precluded formal compartmental analysis. Plasma clearance ranged from 5–12 ml/min/kg, and appeared lower than previously reported volunteer data. The haemodynamic actions of nicardipine (10 mg infusion over 10 min) in 6 patients undergoing diagnostic catheterization were reductions in systolic, diastolic and mean systemic arterial pressure and systemic vascular resistance index. Heart rate and stroke volume index increased, and there was a small but statistically significant increase in pulmonary artery occluded pressure. Radionuclide parameters were measured in 20 patients with stable angina, at rest and during supine bicycle exercise, before and 3–5 min after nicardipine 10 mg intravenously. The left ventricular ejection fraction increased by 4% at rest but not during exercise. The left ventricular rest and exercise ejection and filling rates both increased with a concurrently reduced left ventricular ejection time. There was a highly significant inverse relationship between baseline exercise ejection fraction and the response to nicardipine; ejection fraction increased with low initial values but was either unchanged or fell with higher initial values. These data suggest that the acute effects of nicardipine in stable coronary artery disease probably reflect a reduction in left ventricular afterload and an associated augmentation of cardiac pumping performance. The acute circulatory profile of nicardipine appears sufficiently promising to warrant longer-term studies in ischaemic heart disease.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-1041
    Keywords: beta-blocking drugs ; coronary artery disease ; myocardial infarction ; haemodynamic response
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Theoretically the increased sympathoadrenal activity following acute myocardial infarction might augment the haemodynamic impact of beta-adrenoceptor blockade. To evaluate this question 32 haemodynamic studies were performed to compare the effects of equivalent beta-blocking doses of propranolol (8 mg i.v.) and pindolol (0.8 mg i.v.) in patients with a recent acute myocardial infarction (A.M.I.) or stable coronary artery disease (and a presumptive low sympathetic state). In stable coronary artery disease there were clear differences between the haemodynamic impact of propranolol and pindolol. Propranolol decreased both heart rate (ΔHR −7 beat/min) and cardiac index (ΔCI −0.4l/min/m2), with an increased pulmonary artery occluded pressure (ΔPAOP +4 mmHg) and systemic vascular resistance index (ΔSVRI +358 dyn · s · cm−5 m2). However an equivalent beta-blocking dose of pindolol increased PAOP (ΔPAOP +3 mmHg) leaving other variables unchanged. These differential actions of propranolol and pindolol have previously been ascribed to the intrinsic synpathomimetic activity (I.S.A.) of pindolol maintaining cardiac pumping function in a low sympathetic state. In contrast following myocardial infarction, both drugs reduced cardiac index to a significantly greater extent compared with stable coronary artery disease (ΔCI propranolol −0.8l/min/m2; pindolol −0.4l/min/m2;p〈0.05); propranolol also reduced the systemic arterial blood pressure (Δsystolic −10 mmHg; Δmean −5 mmHg;p〈0.05). The haemodynamic relevance of the I.S.A. of pindolol appeared attenuated following A.M.I. These data are compatible with experimental evidence of sympathetic nervous activation following coronary occlusion; the resulting hyperadrenergic state appears to condition an augmented haemodynamic response to beta-blocking drugs irrespective of their ancillary pharmacological properties. The implications of these findings for clinical therapy warrant further examination.
    Type of Medium: Electronic Resource
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