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  • 1
    Electronic Resource
    Electronic Resource
    Langerhans Cells in Actinic Reticuloid (1975)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 2 (1975), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Actinic reticuloid was observed in a patient following the development of porphyria cutanea tarda. A cutaneous lymphoma-like infiltrate was found histologically and at the ultra-structural level. In the infiltrate, the main population was histiocytic, with some mast cells and mononuclear cells. Most of the histiocytic cells contained numerous typical Langerhans granules and worm-like structures. Crystalloid cytoplasmic inclusions were occasionally detected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0560.1975.tb00160.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Evaluation of a 1-h exposure time to mechlorethamine in patients undergoing topical treatment (2002)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 147 (2002), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary Background Mechlorethamine is frequently used in the treatment of cutaneous lymphoma, but its application is limited in 30–80% of cases because of cutaneous intolerance. Reducing the concentration to avoid this side-effect has been only modestly successful. Objectives To investigate whether a shorter application period could reduce the frequency of intolerance. Methods In an open prospective study in 39 patients with cutaneous T-cell lymphoma or parapsoriasis, mechlorethamine was applied according to the usual practices of the participating physicians (number of weekly applications, treatment confined to lesions or performed over the entire body) and then washed off after 1 h in all cases. Results Cutaneous intolerance was observed in 19 of 39 patients (49%). Six of these patients showed allergic contact dermatitis to mechlorethamine after a mean period of 9·3 weeks, while the other 13 developed irritant contact dermatitis after a longer period. Cutaneous intolerance did not differ significantly according to the number of applications per week or the extent of body area treated. The therapeutic response rate was 69%, and no difference in therapeutic efficacy was noted between daily and intermittent applications. Conclusions Comparison with published studies showed no significant difference in the number of cases of cutaneous intolerance after short-term application, although their occurrence was delayed. Therapeutic response was decreased appreciably by short-term application as compared with results in the literature.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2002.04802.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Allergic contact dermatitis from hydrangea – is it so rare? (2000)
    Copenhagen : Munksgaard International Publishers
    Contact dermatitis 43 (2000), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 8 cases of allergic contact dermatitis from hydrangea seen in Angers, France, during the last 15 years are reported and compared to other cases found in the literature. In this review, allergic contact dermatitis from hydrangeas appears to be an occupational dermatosis among nursery workers, presenting as an eczema involving the hands and especially the first 3 fingers, with chronic features of fissuring and scaling and with a chronic course. Differential diagnosis from irritant contact dermatitis may be difficult. Patch tests with the stem as well as the leaf of hydrangeas gave strong positive reactions in all patients, and hydrangenol, the allergen of hydrangea, when tested, always also gave a positive reaction. Sensitization seems to occur after close and prolonged contact with the plant, which could explain the relative frequency in Angers because it provides almost 90% of hydrangea seedling production in France.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0536.2000.043004189.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Granuloma Faciale (1977)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 4 (1977), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Light and electron microscopic observations were carried out in three cases of granuloma faciale. The dense granulomatous infiltrate of the corium showed: 1) more eosinophils than suspected by light microscopy, most of them with degenerative changes; 2) Charcot-Leyden chrystals; 3) numerous large histiocytes with their cytoplasms filled with lysosomal vesicles containing various inclusions (lamellar figures, myelin bodies, circular concentric organelles, digested membrane structures). The lack of Langerhans granules in dermal cells seems a valid reason to differentiate granuloma faciale from eosinophilic granuloma of the skin, usually considered a variety of histiocytosis X. No evidence of bacterial or viral infections was noticed. Granuloma faciale, despite its uncertain etiology, seems to represent a true entity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0560.1977.tb00898.x
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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