ISSN:
1744-313X
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Biology
,
Medicine
Notes:
An alloantigen segregating in the double back-cross families, distinct from serologically determinable transplantation antigens controlled by the major histocompatibility complex (SLA), was detected in pigs by the complementdependent lymphocytotoxic technique. The system was designated SLB and its product (antigen SLB-Al) was demonstrated in all lymphocytes from the lymph nodes, thymus and peripheral blood, but not in the erythrocytes. Back-cross matings supplied evidence of the dominant heredity of SLB-Al. Detection of further SLB antigens was unsuccessful, so that only two alleles (SLB-Al and SLB-A-) could be determined in families. Double back-cross families revealed a close linkage between the SLB locus and the L blood group locus. Maximum lod score values were calculated in recombination fraction θ= 0.10.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1744-313X.1978.tb00643.x
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