ISSN:
1573-4951
Keywords:
Phosphodiesterase inhibitors
;
Cyclic nucleotides
;
Molecular modelling
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary Modelling studies have been carried out on the phosphodiesterase (PDE) substrates, adenosine- and guanosine-3′5′-cyclic monophosphates, and on a number of non-specific and type III-specific phosphodiesterase inhibitors. These studies have assisted the understanding of PDE substrate differentiation and the design of potent, selective PDE type III inhibitors.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01676955
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