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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 12 (1987), S. 0 
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Thirty-five patients with acne vulgaris were studied regarding vitamin A and E status, and the safety and efficacy of vitamin A supplementation over a 6-week period. The patients studied had significantly lower plasma vitamin A levels than normal controls and a lower frequency of consumption of foods rich in vitamin A. Vitamin E status in the patients was similar to that of normal controls. Vitamin A supplementation had no significant effect on plasma vitamin A levels during the study, but the patients had significantly (P〈0.005) higher levels at 6 weeks post-supplementation when compared with pre-supplementation values. Furthermore, vitamin A supplementation was associated with a significant and progressive increase in plasma retinol ester concentration. Vitamin A at the dose administered was ineffective in the treatment of acne and was associated with symptoms compatible with hypervitaminosis A only in a small percentage of patients.
    Type of Medium: Electronic Resource
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