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  • 1
    Electronic Resource
    Electronic Resource
    Mast cell desensitization to IgE fails to induce a parallel adenosine receptor desensitization (1993)
    Springer
    Inflammation research 40 (1993), S. 11-17 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Desensitization induced by challenge of mast cells with antigen is specific for IgE-dependent signals. During the secretory process mast cells release adenosine, which can induce a desensitization of adenosine receptors. To determine whether adenosine receptors may de desensitized from a previous antigen challenge, mast cells were sensitized with anti-DNP IgE antibody, challenged with DNP-BSA antigen, returned to culture overnight, resensitized, and rechallenged. Previously challenged cells exhibited increased spontaneous β-hexosaminidase release, but adenosine retained its ability to augment β-hexosaminidase release. Adenosine enhanced A23187-stimulated release of β-hexosaminidase in control and previously challenged cells. Leukotriene C4 generation followed a similar pattern. Mastoparan, a direct G protein activator and mast cells secretogogue, produced a doubling of β-hexosaminidase release in previously challenged cells. Results using other G protein activators were equivocal. Degranulation alone is insufficient to induce adenosine receptor hyposensitization. Whether the hyperresponsiveness to mastoparan is a consequence of uncoupling of IgE receptors from G proteins remains uncertain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01976746
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  • 2
    Electronic Resource
    Electronic Resource
    The effect of urocortin on ingestive behaviours and brain Fos immunoreactivity in mice (2003)
    Oxford, UK : Blackwell Science, Ltd
    European journal of neuroscience 18 (2003), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The influence of urocortin (UCN) on ingestive behaviours and brain neural activity, as measured immunohistochemically by the presence of Fos protein, was determined in mice. Rat UCN was administered by continuous intracerebroventricular (ICV) or subcutaneous (SC) infusion. ICV infusion of UCN (100 ng/h, 14 days) transiently reduced daily food and water intakes (days 1–4) but body weight was reduced from day 2 into the post-infusion period. Sodium intake was reduced from day 3 to the end of infusion. SC infusion of UCN caused similar but smaller reductions in food and water intakes and body weight, without change in sodium intake. In separate experiments, Fos immunoreactivity was increased in several brain nuclei known to be involved in the control of body fluid and energy homeostasis, e.g. central nucleus of the amygdala, median preoptic nucleus, bed nucleus of the stria terminalis and arcuate nucleus. Increased Fos expression was similar for ICV and SC infusions when measured on days 2–3 or 6–7 of infusion. In conclusion, increases of brain activity by UCN may be associated with stimulation of adrenocorticotrophic hormone release and sympathetic nervous activity, but increases may also indicate suppression of ingestive behaviours by stimulating central inhibitory mechanisms located in areas known to control body fluid and energy homeostasis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1460-9568.2003.02760.x
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  • 3
    Electronic Resource
    Electronic Resource
    ALTERED BLOOD PRESSURE, RENAL TUBULAR FUNCTION AND LEVELS OF CIRCULATING INHIBITORS OF Na-K-ATPase IN MATURE SHR EXPOSED TO LOW SALT DIET IN THE PERINATAL PERIOD (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 20 (1993), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. It has been shown previously that low salt diet, confined to the perinatal period only, reduces blood pressure (BP) and sodium retention in spontaneously hypertensive rat (SHR) offspring at maturity when compared with those given high salt diet.2. In this study it is shown that such high salt diets are associated with an increased level of circulating Na-K-ATPase inhibitor (CINK) activity.3. Animals given perinatal high salt diet have a significantly greater tubular reabsorptive capacity when compared with those given low salt diet.4. The finding of a high level of circulating Na-K-ATPase inhibitory material in the face of increased renal tubular capacity and blood pressure suggests that while this inhibitory material may play a role in the elevated blood pressure of animals given high salt diet, it cannot cause the elevated rate of fluid reabsorption.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1993.tb01701.x
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  • 4
    Electronic Resource
    Electronic Resource
    Fracture behavior of core-shell rubber-modified crosslinkable epoxy thermoplastics (1994)
    Springer
    Colloid & polymer science 272 (1994), S. 456-466 
    Details
    ISSN: 1435-1536
    Keywords: Rubber modification ; low crosslink density highT g epoxy ; toughening mechanisms ; double-notch four-point-bend ; fatigue fracture
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The fracture behavior of a core-shell rubber (CSR) modified cross-linkable epoxy thermoplastic (CET) system, which exhibits high rigidity, highT g, and low crosslink density characteristics, is examined. The toughening mechanisms in this modified CET system are found to be cavitation of the CSR particles, followed by formation of extended shear banding around the advancing crack. With an addition of only 5 wt.% CSR, the modified CET possesses a greater than five-fold increase in fracture toughness (G IC) as well as greatly improved fatigue crack propagation resistance properties, with respect to those of the neat resin equivalents. The fracture mechanisms observed under static loading and under fatigue cyclic loading are compared and discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00659459
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  • 5
    Electronic Resource
    Electronic Resource
    Organometallic polymers. XXV. Preparation of polyvinylferrocene (1973)
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Chemistry Edition 11 (1973), S. 1213-1224 
    Details
    ISSN: 0360-6376
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The synthetic details of solution polymerization in benzene and bulk polymerization of vinylferrocene are reported. In benzene solutions, with azobisisobutyronitrile (AIBN) as the initiator, small yields of low-polydispersity low molecular weight (M̄n ≃ 5000) polyvinylferrocene is obtained. However, high yields can be obtained by continuous or multiple AIBN addition. Higher molecular weight polymers and binodal polymers can be obtained as the monomer concentration is increased. In bulk polymerizations, yields of 80% can be obtained. The molecular weight increases as temperature decreases from 80 to 60°C in bulk polymerizations, and an increasing amount of insoluble polymer results. The soluble portion is often binodal, the higher molecular weight node consisting of an increasingly branched structure. Lower molecular weight polymer was readily fractionated into narrow fractions from benzene-methanol systems, but higher molecular weight polymer proved impossible to fractionate into narrow fractions due to branching.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pol.1973.170110609
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  • 6
    Electronic Resource
    Electronic Resource
    Meta-bromobiphenol epoxy resins: Applications in electronic packaging and printed circuit board (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 43 (1991), S. 1315-1321 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Novel 2,2′,6,6′-tetrabromo-3,3′,5,5′-tetramethyl-4,4′-biphenol (TBTMBP), and its epoxy derivatives, were synthesized to incorporate the stable meta-brominated phenol moiety into epoxy resin systems. In electronic encapsulation and laminate applications, epoxy systems derived from TBTMBP have exhibited superior hydrolytic and thermal stability as compared with the conventional ortho-brominated epoxy resins. These properties have resulted in an extended device life for semiconductors and a high Tg with excellent blister resistance for the printed circuit board, while meeting flame retardancy requirements as well.
    Additional Material: 6 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1991.070430713
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