ISSN:
0018-019X
Schlagwort(e):
Chemistry
;
Organic Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
The preparation of the diastereoisomers of 1-amino-2-bromocyclopropanecarboxylic acid is described using the methyl (1RS, 5SR)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate 5 as starting material. The key step is the oxidation of 9 with subsequent radical introduction of bromine according to the Barton procedure. The 2-bromo-cyclopropanecarboxylates cis-11 and trans-11 were obtained as diastereoisomer mixture in a ratio of 3:1. They were converted into cis- and trans-esters 12 and the acids 13.
Zusätzliches Material:
1 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/hlca.19950780211
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