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Digitale Medien

Efficacy of Single Lead VDD Pacing in Patients with Impaired and Normal Left Ventricular Function (2000)

SCHUCHERT, ANDREAS ; JAKOB, MICHAEL ; TREESE, NOBERT ; [weitere]

Oxford, UK : Blackwell Publishing Ltd

Pacing and clinical electrophysiology 23 (2000), S. 0

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ISSN: 1540-8159

Quelle: Blackwell Publishing Journal Backfiles 1879-2005

Thema: Medizin

Notizen: Atrial synchronous ventricular pacing seems to be the best pacing mode for patients with advanced AV block and impaired LV function. The long-term follow-up of single lead VDD pacing was studied in 33 patients with impaired LV function and compared to 42 patients with normal LV function. All patients received the same VDD lead and VDDR pacemaker. The lead model with 13-cm AV spacing between the atrial and ventricular electrode was implanted in 89% of the patients. Follow-ups were 1, 3, 6, and 12 months after implantation. The percentage of atrial sensing and the P wave amplitude were determined at each follow-up. Minimal P wave amplitude at implantation was 2.0 ± 1.4 mV in patients with impaired and 1.7 ± 0.9 mV with normal LV function (not significant). At the 12-month follow-up, 33 patients with normal and 23 patients with depressed LV function remained paced in the VDD mode. The remaining patients died in five (impaired LV function) and seven cases (normal LV function) or their pacemakers were programmed to the VVI/VVIR pacing mode in four (impaired LV function) and three cases (normal LV function). P wave amplitude did not differ in the two groups (e.g., at month 12: impaired: 1.17 ± 0.42 mV; normal: 1.09 ± 0.49 mV). The atrial sensitivity was programmed in most patients to sensitive settings with no differences between the two groups (e.g., at month 12: impaired: 0.13 ± 0.06 mV; normal: 0.13 ± 0.05 m V). The diagnostic counters indicated nearly permanent atrial sensing (e.g., at month 12: impaired: 99.3 ± 2.2%; normal: 99.0 ± 1.0 mV). In conclusions, single lead VDD pacing restored AV synchronous ventricular pacing in patients with normal and with impaired LV function indicating that it could be an alternative to DDD pacemakers, but not to dual-chamber pacing.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1111/j.1540-8159.2000.tb00941.x

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Digitale Medien

Clinical Evaluation of a Thin Bipolar Pacing Lead (1997)

BREIVIK, KJELL ; DANILOVIC, DEJAN ; OHM, OLE-JØRGEN ; [weitere]

Oxford, UK : Blackwell Publishing Ltd

Pacing and clinical electrophysiology 20 (1997), S. 0

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ISSN: 1540-8159

Quelle: Blackwell Publishing Journal Backfiles 1879-2005

Thema: Medizin

Notizen: The main disadvantages of bipolar pacing leads have traditionally been related to their relative thickness and stiffness compared to unipolar leads. In a new “drawn filled tube” plus “coated wire” technology, each conductor strand is composed of MP35N tubing filled with silver core and coated with a thin ETFE polymer insulation material. This and parallel winding of single anode and cathode conductors into a single bifilar coil resulted in a bipolar lead (ThinLine, Intermedics) with a body diameter and flexibility similar to unipolar leads. The lead is tined. polyurethane. with the cathode and the anode made of iridium-oxide-coated titanium (IROX). The slotted 8-mm2 cathode tip is coated with polyethylene glycol. a blood soluble material. We present the clinical evaluation results from four pacemaker clinics, where 47 leads (23 atrial-J model 432–04 and 24 ventricular model 430–10) were implanted in 25 patients and followed for up to 2 years. The lead handling characteristics were found to be very satisfactory. Electrical parameters of the leads were measured at implant and noninvasively on postoperative days 1, 2, 21, 42. and months 3, 6, 12, and 24. Mean chronic pulse width thresholds at 2.5 V were 0.14 ± 0.05 ms in the atrium and 0.10 ± 0.02 ms in the ventricle, pacing impedances 443 ± 104 Ω and 520 ± 241 Ω. while median electrogram amplitudes were ≥ 3.5 mV and ≥ 7 m V, respectively. Pacing impedances and thresholds were found to be slightly but statistically significantly higher in unipolar than in bipolar configuration—the findings are explainable bv the lead construction. One of 47 leads failed 3 weeks after implant; the conductors were short circuited due to an error during the manufacturing process. We conclude that the new lead thus far has demonstrated appropriate mechanical and electrical characteristics.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1111/j.1540-8159.1997.tb03882.x

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Unbekannt

EAST ASIA IN AMERICAN FOREIGN POLICY. By Stephen P. Gibert and William M. Carpenter (Book Review) (1992)

Wilhelm, Alfred D. 〈Jr〉

Honolulu, etc. : Periodicals Archive Online (PAO)

Pacific Affairs. 65:2 (1992:Summer) 247

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ISSN: 0030-851X

Thema: Politikwissenschaft , Sociologie , Wirtschaftswissenschaften

Notizen: Asia General

URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:5082-1992-065-02-000005

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Digitale Medien

Spirobipyrane aus o-Hydroxyarylvinylpyryliumsalzen (1969)

Schiele, Cajetan ; Wilhelm, Alfred ; Paal, Gabor

Weinheim : Wiley-Blackwell

Liebigs Annalen 722 (1969), S. 162-172

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ISSN: 0075-4617

Schlagwort(e): Chemistry ; Organic Chemistry

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Chemie und Pharmazie

Beschreibung / Inhaltsverzeichnis: Spirobipyrans from o-Hydroxyarylvinylpyrylium SaltsStructurally defined o-hydroxyarylvinylpyrylium salts can be cyclized to spirobipyrans of type 1-5 and to the hitherto unknown 2,2′-spirobi[2H-naphtho[1,2-b]pyrans] (6). Asymmetric monosubstituted spirobipyrans of type 2, 3, and 5 show a correlation between thermochromism and position of the substituent (Table 1).

Notizen: Strukturspezifisch aufgebaute o-Hydroxyarylvinylpyryliumsalze werden zu Spirobipyranen der Typen 1-5 und zu den bisher unbekannten 2.2′-Spirobi[2H-naphtho[1.2-b]pyranen] (6) cyclisiert. Bei asymmetrisch aufgebauten, monosubstituierten Spirobipyranen der Typen 2, 3 und 5 wird ein Zusammenhang zwischen Thermochromie und Anordnung des Substituenten beobachtet (Tab. 1).

Zusätzliches Material: 8 Tab.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/jlac.19697220116

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