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The Dynamic Performances of DDTs in the Environment and Japanese Exposure to Them: A Historical Perspective after the Ban (2002)

Morisawa, Shinsuke ; Kato, Atsushi ; Yoneda, Minoru ; [et al.]

Oxford, UK : Blackwell Publishing, Inc

Risk analysis 22 (2002), S. 0

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ISSN: 1539-6924

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Energy, Environment Protection, Nuclear Power Engineering

Notes: The fugacity model for evaluating DDTs dynamic performances in the environment was combined with the dietary exposure evaluation model, including the contribution of imported food, to develop the macroscopic mathematical model relating DDTs in the environment with the health risks of the reference Japanese. The model validity was examined by comparing the simulated DDTs concentrations in environmental media, various kinds of food, and dietary intake with those observed. Numerical simulations were done for the past half and future of one century to evaluate the effect of the DDTs usage prohibition in 1970 in Japan. The major results obtained under the limits considered are as follows. The DDTs concentrations in environmental media, various kinds of foods, and the dietary intake showed the steady exponential decrease after the DDTs usage prohibition in 1970. The DDE/DDTs ratio is larger in the higher position in an ecological system, and increased steadily with time. The critical exposure of DDTs occurred through animal product intake until 1960; after 1990 marine product intake caused the most exposure. The estimated DDTs intake was evaluated to be less than the PTDI and RfD. The annual excess cancer induction risk due to the annual dietary intake of DDTs was the largest at the level of (0.5−2.0)×10−6 (1/yr) in the early 1970s. The effect of the DDT usage prohibition on dietary exposure reduction was expected to appear after about 20 years. The life-span excess cancer induction risk was conservatively estimated to be larger than 10−5 (1/lifespan) for the reference Japanese who were born before 1970. The DDTs usage prohibition in 1970 was effective to reduce the life-span cancer risk under the 10−5 level.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/0272-4332.00019

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Spondyloepiphyseal dysplasia congenita (1978)

Sugiura, Yasuo ; Terashima, Yoji ; Furukawa, Takemitsu ; [et al.]

Springer

International orthopaedics 2 (1978), S. 47-51

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ISSN: 1432-5195

Keywords: Spine ; Hip joint ; Spondyloepiphyseal dysplasia congenita

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Description / Table of Contents: Résumé Présentation de neuf cas de dysplasie spondylo-épiphysaire congénitale, observés chez des enfants japonais. La dysplasie spondylo-épiphysaire congénitale se différencie de la maladie de Morquio par son apparition plus précoce, ses images radiologiques caractéristiques, ainsi que par l'absence d'opacités cornéennes et de kératosulfaturie.

Notes: Summary Nine cases of SED congenita seen in Japanese children are presented. SED congenita was differentiated from Morquio's disease by its earlier manifestation, its characteristic radiographic features, the lack of corneal clouding and the absence of keratosulphaturia.