Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Very low density lipoprotein subfractions in Type II diabetes mellitus: alterations in composition and susceptibility to oxidation (2000)
    Springer
    Diabetologia 43 (2000), S. 485-493 
    Details
    ISSN: 1432-0428
    Keywords: Keywords Lipid and fatty acid composition, lag time, preformed peroxides.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Aims/hypothesis. Type II (non-insulin-dependent) diabetes mellitus is associated with raised triglycerides and increased very low density lipoprotein cholesterol. The aim of this study was to assess if very low density lipoprotein subfraction composition and potential to oxidise were altered in this condition.¶Methods. Very low density lipoprotein was separated into four subfractions (A→D) by a novel, rapid ultracentrifugation procedure. Analysis of each subfraction included lipid and fatty acid composition. Preformed peroxides were measured spectrophotometrically and conjugated dienes were used as an indicator of in vitro lipid oxidation.¶Results. In all results we compared patient and control subfractions. Mean fasting plasma glucose was 8.9 ± 2.0 mmol/l in patients vs 5.1 ± 0.4 mmol/l in control subjects (p 〈 0.001); patient HbA1 c was 7.6 ± 1.4 %. Patient total lipid standardised for apo B was higher than controls in subfractions A, B and C; A, 201 vs 60; B, 191 vs 40; C, 63 vs 21; D, 29 vs 34 μmol lipid per mg apo B (p 〈 0.05). Preformed peroxides were higher in all patient subfractions compared with controls: A, 340 vs 48; B, 346 vs 42; C, 262 vs 28; D, 54 vs 16 nmol per mg apo B (p 〈 0.001). Patient subfractions A and D were more susceptible to in vitro oxidation. Monounsaturated fatty acids were lower in patients subfractions, 35.2 vs 36.7; B, 35.1 vs 38.7; C, 34.4 vs 36.5; D, 33.0 vs 35.5 as per cent total (p 〈 0.05).¶Conclusions/interpretation. These results indicate abnormalities in very low density lipoprotein subfraction composition and oxidation profile in Type II diabetic subjects, which are characteristic of more atherogenic particles and that may contribute to the development of cardiovascular disease in these patients. [Diabetologia (2000) 43: 485–493]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001250051333
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Antioxidant status of oral mucosal tissue and plama levels in smokers and non-smokers (1999)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 28 (1999), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The antioxidant status of an individual is thought to be important in the development of potentially malignant oral lesions (PMOL) and oral squamous cell carcinoma (OSCC). To date, little detailed information on mucosal antioxidant status is available in a United Kingdom population and neither has the relationship between smoking and mucosal antioxidant status been established. Furthermore, it has been implied that serum levels of antioxidants and tissue levels in the oral mucosa should be equivalent, but that is unproven. To address these deficiencies in our knowledge we studied 60 individuals, all of whom had an oral mucosal biopsy and simultaneous vanous blood sampling. Antioxidant levels were measured using high performance liquid chromatogaphy. Smokers (n=19) were found to have significantly lower levels of plasma β-carotene (P〈0.05) and significantly lower levels of tissue α-carotene (P〈0.05) than non-smokers (n=41). Tissue α-carotene correlated with plasma levels, but this was not the case with α-tocopherol, retinol, lycopene or β-carotene. This is the first data on oral mucosal antioxidant levels and provides baseline data from which to study patients with potentially malignant oral lesions and oral squamous cell carcinoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1999.tb02054.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Isometric and isotonic muscle properties as determinants of work loop power output (1996)
    Springer
    Pflügers Archiv 432 (1996), S. 767-774 
    Details
    ISSN: 1432-2013
    Keywords: Key words Muscle ; Work ; Power ; Isotonic shortening ; Work loops ; Muscle mechanics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The power output of rabbit latissimus dorsi muscle was calculated under isotonic conditions and during oscillatory work. Isotonic shortening studies yielded a maximum power output of 120 W·kg−1 at a P/P 0 of 0.4 compared to a maximum power output of 32 W·kg−1 obtained using the work loop technique. This difference can largely be explained by comparing actual work loops with those constructed using force velocity (P/V) and isometric data. At low cycle frequencies, work loop power output is quite close to that predicted from P/V and isometric data. However, at higher frequencies other dynamic muscle properties appear to exert a more marked effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004240050197
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...