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  • 1
    ISSN: 1619-7089
    Keywords: Radionuclide angiography ; Ejection fraction ; Contrast angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract First-pass radionuclide angiography (FPRA) in the 30° right anterior oblique and equilibrium gated radionuclide angiography (EGNA) in the 45° left anterior oblique were used for quantitative measurements of left ventricular ejection fraction (LVEF). Equipment used was a 400T gamma-camera interfaced with a Simis III Informatek computer. The results were compared with contrast angiography (CA). The aim of this study was to determine the sensitivity of both radionuclide techniques. The present data are based on 65 patients in whom CA and EGNA were performed. In 47 patients both FPRA and EGNA were performed. Results suggested that in ischemic heart disease (IHD) and valvular heart disease (VHD) the EGNA technique is well correlated with CA (r=0.9 and 0.73, respectively). FPRA correlated well only with CA in IHD (r=0.86), but not in VHD (r=0.18). This study indicates that both FPRA and EGNA are sensitive, noninvasive techniques for measuring ejection fraction in IHD, while in VHD, EGNA is more sensitive technique than FPRA.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1619-7089
    Keywords: 99mTc-MIBI ; Myocardial imaging ; Ischaemic heart diseases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To study the potential usefulness of99mTc-methoxy isobutyl isonitrile (99mTc-MIBI) as a substitute for201Tl in assessing patients with ischaemic heart disease, 24 patients underwent 1 day rest and exercise99mTc-MIBI single photon emission computerised topography (SPECT) 1 week after SPECT exercise201Tl. All patients were catheterized within 1 month after myocardial imaging. In 17 patients, resting first pass radionuclide angiography (FPRNA) was performed with99mTc-MIBI. The heart to lung ratio for99mTc-MIBI and201Tl was calculated both at rest and exercise. The segmental analysis for myocardial perfusion reveals that 87/96 segments (91 %) were correctly classified by SPECT201Tl and 84/96 segments (88%) were correctly classified by99mTc-MIBI. A significant correlation was present between LVEF measured by99mTc-MIBI FPRNA and contrast ventriculography (r = 0.85,P 〈 0.0001). The heart to lung ratio both at rest and exercise for99mTc-MIBI is significantly higher than201Tl (P 〈 0.01 and 〈0.001 respectively). We conclude that99mTc-MIBI is a promising agent for simultaneous evaluation of myocardial perfusion and cardiac function.
    Type of Medium: Electronic Resource
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