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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Chromatographia 42 (1996), S. 405-408 
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Meropenem in rat plasma ; Column-switching
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary The purpose of this study was to develop a columnswitching HPLC method for the determination of meropenem in plasma. This method showed excellent precision and accuracy with good sensitivity and speed. The total analysis time per sample was less than 20 min and the mean coefficients of variation for intra- and inter-assay were less than 4.0%. The method has been successfully applied to plasma samples from rats receiving an intraperitoneal injection of meropenem.
    Type of Medium: Electronic Resource
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