ISSN:
1612-1112
Keywords:
Column liquid chromatography
;
Meropenem in rat plasma
;
Column-switching
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary The purpose of this study was to develop a columnswitching HPLC method for the determination of meropenem in plasma. This method showed excellent precision and accuracy with good sensitivity and speed. The total analysis time per sample was less than 20 min and the mean coefficients of variation for intra- and inter-assay were less than 4.0%. The method has been successfully applied to plasma samples from rats receiving an intraperitoneal injection of meropenem.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02272131
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