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  • 1
    Electronic Resource
    Electronic Resource
    New Topological Index and Prediction of Phase Transfer Energy for Protonated Amines and Tetraalkylammonium Ions (1995)
    s.l. : American Chemical Society
    Journal of chemical information and modeling 35 (1995), S. 45-49 
    Details
    ISSN: 1520-5142
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ci00023a006
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  • 2
    Electronic Resource
    Electronic Resource
    Changes in Lipogenic Capacity and Activities of Ketolytic and Lipogenic Enzymes in Brain Regions of Developing Rats (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 40 (1983), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Oxidation of ketone bodies (KBs) generates acetyl coenzyme A (AcCoA), which can be further incorporated into fatty acid. We have determined the rates of lipogenesis from ketone bodies in developing rats and their relation to the activities of enzymes involved in the production of cytoplasmic AcCoA via different pathways in brain regions. In the cerebrum (Cbr), rates of fatty acid synthesis from [3-14C]acetoacetate ([3-14C]AcAc) were high during the early postnatal period but decreased rapidly thereafter until weaning. Although similar developmental patterns of synthesis characterized the cerebellum (Cbl), midbrain (Mb), brain stem (Bs), and thalamus (Th), maximal rates were highest in the Cbr and lowest in the Th. In all regions, synthetic rates were higher throughout the entire suckling period than in adulthood. There were no appreciable differences in synthetic rates among brain regions of adult rats. The developmental changes in rates of AcAc incorporation into fatty acids were closely related to AcAcCoA synthetase activity, but not to activities of ATP-citrate lyase or AcCoA synthetase. During the early postnatal stage the enhanced rates of lipogenesis were accompanied by increased activities of AcAcCoA synthetase in all regions, with the highest activity occurring in the Cbr. The sequence of reactions coupling AcAcCoA synthetase and AcAcCoA thiolase in cytoplasm may be an important pathway for generation of AcCoA from KBs for fatty acid synthesis in all regions of the developing brain. This interpretation is strengthened by evidence of concomitant increases in the activities of fatty acid synthetase and AcCoA carboxylase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1983.tb12658.x
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  • 3
    Electronic Resource
    Electronic Resource
    Increased expression of lung resistance-related protein in lower grade urothelial carcinoma of the renal pelvis and ureter (2004)
    Melbourne, Australia : Blackwell Science Pty
    International journal of urology 11 (2004), S. 0 
    Details
    ISSN: 1442-2042
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Background: Lung resistance-related protein (LRP), like multidrug resistance gene 1 (MDR1) and multidrug resistance-associated proteins (MRP), has been associated with intrinsic therapeutic resistance in various malignancies. To date, there has been no study on the expression of LRP in urothelial carcinomas of the renal pelvis and ureter. We investigated the protein and mRNA expression levels of LRP, MDR1 and MRP1 in this malignancy and the clinical significance of their expression was evaluated.Methods: Forty urothelial carcinomas of the renal pelvis and ureter and 31 normal upper urothelial samples were examined by immunohistochemistry and reverse transcription polymerase chain reaction to determine the protein and mRNA levels of the multidrug resistance-related genes, respectively.Results: The positive staining rates and mRNA levels of LRP were the highest among these multidrug resistance-related genes in both normal urothelium and carcinoma examinations. In contrast to the up-regulated expression of MDR1, the expression of LRP tended to be down-regulated in carcinomas. Moreover, the expression of LRP inversely correlated with tumor grades, but this correlation was not found for the other two genes. However, there was no correlation among the expression of the three genes observed.Conclusion: Lung resistance-related protein was strongly expressed in urothelial carcinomas of the renal pelvis and ureter, particularly in well-differentiated carcinomas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1442-2042.2004.00874.x
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  • 4
    Electronic Resource
    Electronic Resource
    The nuclear hormone receptor Ftz-F1 is a cofactor for the Drosophila homeodomain protein Ftz (1997)
    [s.l.] : Nature Publishing Group
    Nature 385 (1997), S. 552-555 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ftz is a segmentation gene of the pair-rule class located in the Antennapedia (Antp) complex4. Although its homeodomain and in vitro binding specificity is very similar to other Antp-class proteins5'6, its role in embryos is unique: loss-of-function ftz mutations produce deletions of even-numbered ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/385552a0
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  • 5
    Electronic Resource
    Electronic Resource
    Biosynthesis of lung lipids from acetoacetate and glucose in the developing rat in vivo
    Amsterdam : Elsevier
    International Journal of Biochemistry 14 (1982), S. 81-86 
    Details
    ISSN: 0020-711X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0020-711X(82)90147-1
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  • 6
    Electronic Resource
    Electronic Resource
    Genome-wide expression analysis of iron regulation in Burkholderia pseudomallei and Burkholderia mallei using DNA microarrays (2005)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 252 (2005), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Burkholderia pseudomallei and B. mallei are the causative agents of melioidosis and glanders, respectively. As iron regulation of gene expression is common in bacteria, in the present studies, we have used microarray analysis to examine the effects of growth in different iron concentrations on the regulation of gene expression in B. pseudomallei and B. mallei. Gene expression profiles for these two bacterial species were similar under high and low iron growth conditions irrespective of growth phase. Growth in low iron led to reduced expression of genes encoding most respiratory metabolic systems and proteins of putative function, such as NADH-dehydrogenases, cytochrome oxidases, and ATP-synthases. In contrast, genes encoding siderophore-mediated iron transport, heme-hemin receptors, and a variety of metabolic enzymes for alternative metabolism were induced under low iron conditions. The overall gene expression profiles suggest that B. pseudomallei and B. mallei are able to adapt to the iron-restricted conditions in the host environment by up-regulating an iron-acquisition system and by using alternative metabolic pathways for energy production. The observations relative to the induction of specific metabolic enzymes during bacterial growth under low iron conditions warrants further experimentation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/j.femsle.2005.09.043
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  • 7
    Electronic Resource
    Electronic Resource
    Study on Cavity Growth in Uniaxial Tension of ZK60 Magnesium Alloy (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 353-358 (Sept. 2007), p. 687-690 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Cavity growth is a typical microstructure feature in superplastic forming (SPF) ofmaterials. Substantial growth and interlink of cavities in superplastic deformation usually lead toreduction in elongation, even to failure. Consequently, it is necessary to investigate themechanism and model of cavity growth. In this paper, experimental studies on cavity growth werecarried out by means of superplastic tension of ZK60 magnesium alloys. Scanning electronicmicroscope (SEM) was employed for observation of fractography. Experimental cavity radius andvolume fraction were determined by optical microscopy and corresponding picture-based analysissoftware. It is found that, the fractured surfaces after a superplastic elongation have a mixedcharacteristic of intergranular cavities and dimples. Further, the cavity growth is identified to followa exponentially increasing mode
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/55/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.353-358.687.pdf
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  • 8
    Electronic Resource
    Electronic Resource
    Fatigue Damage of Materials with Small Crack Calculated by the Ratio-Method under Cyclic Loading (2005)
    s.l. ; Stafa-Zurich, Switzerland
    Advanced materials research Vol. 9 (Sept. 2005), p. 79-86 
    Details
    ISSN: 1662-8985
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper offers some new calculating equations on the small crack growth rate for describing the elastic-plastic behavior of materials under symmetric or un-symmetric cyclic loading. And it yet suggests the estimating formulas of the life relative to varied small crack size aoi at each loading history. The method is to adopt the ratio e p e e D D / by plastic strain range to elastic strainrange as a stress-strain parameter, using some staple material parameters as the material constants in damage calculating expression. And it gives out a new concept of the composite material constant, that it is functional relation with each staple material constants, average stress，average strain and critical loading time. The calculated results are accordant with the Landgraf’s equation, so could avoid unnecessary fatigue tests and will be of practical significance to stint times, manpower and capitals, the convenience for engineering applications
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/41/transtech_doi~10.4028%252Fwww.scientific.net%252FAMR.9.79.pdf
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  • 9
    Electronic Resource
    Electronic Resource
    Synthesis of Aluminium Titanate Ceramics from Waste Sludge of Aluminium Factory (2008)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 368-372 (Feb. 2008), p. 1538-1540 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Aluminium titanate was synthesized using waste aluminium sludge and chemical pure TiO2powder as raw materials. Effect of different compositions on crystal structure and contents of targetproduct was discussed. XRD results showed that four crystal phases, aluminium titanate, perovskite,rutile and aluminum oxide, are formed in the sintered samples. The content of aluminium titanateincreases first and then decreases with the decrease of the content of waste aluminum sludge. When thecontent of the sludge is 65.52wt%, the content of aluminium titanate reaches the maximum of 86.1wt%
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/56/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.368-372.1538.pdf
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  • 10
    Electronic Resource
    Electronic Resource
    Low Temperature Electrolyte for Li-Ion Batteries (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 336-338 (Apr. 2007), p. 530-532 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Electrolyte of LiPF6-ethylene carbonate (EC)-methyl acetate (MA) was prepared. 1 MLiPF6-EC-MA electrolyte presented the conductivity in excess of 1 mS cm-1 at -50 oC. The cyclicvoltammetry showed that the electrolyte was better than conventional electrolyte of LiPF6-ethylenecarbonate (EC)-diethyl carbonate (DEC) for the formation of SEI film. 1 M LiPF6-EC-MA electrolyteshowed much better cycleability than conventional electrolyte of 1 M LiPF6-EC-DE·C for LiCoO2/Li cell.It is a promising alternative electrolyte for Li-ion batteries
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/53/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.336-338.530.pdf
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