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  • 1
    Electronic Resource
    Electronic Resource
    Fluorescence Microscopy of Lysosomes and Related Structures in Living Cells (1966)
    [s.l.] : Nature Publishing Group
    Nature 212 (1966), S. 425-426 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] As has been known for nearly 20 years, a great number of granules with bright red fluorescence appear in the cytoplasm of a living cell treated with acridine orange (2,8 fcs-dimethylaminoacridine) (refs. 1-4; for reviews see refs. 5 and 6). A sharp controversy about the nature of these granules ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/212425a0
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  • 2
    Electronic Resource
    Electronic Resource
    Inhibition of Protein Synthesis by Acridine Orange (1964)
    [s.l.] : Nature Publishing Group
    Nature 204 (1964), S. 45-46 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE interaction of acridine diamino derivatives with nucleic acids has been extensively investigated, particularly in vitro1-5. It is not yet known, however, how these substances affect the synthesis of protein. We have examined this problem autoradiographically having chosen as an active ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/204045a0
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  • 3
    Electronic Resource
    Electronic Resource
    Influence of a specific histone kinase on the physico-chemical properties of chromatin In situ (1975)
    Springer
    Molecular biology reports 2 (1975), S. 241-245 
    Details
    ISSN: 1573-4978
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The influence of a specific histone kinase, phosphorylating lysine-rich histone F1, F2a2, F2b, on the physico-chemical properties of the chromatin in the whole undestroyed fixed cell, has been investigated. It was found that the exogenous histone kinase penetrates into the nuclei of the undestroyed fixed cells and into the isolated unfixed nuclei and changes the physico-chemical properties of the chromatin there, bringing about an increase in binding of a basic dye acridine orange and a decrease in its stability to heat.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00356994
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  • 4
    Electronic Resource
    Electronic Resource
    Comparative properties of rat liver chromatinin situ andin vitro at early stages after partial hepatectomy (1978)
    Springer
    Molecular biology reports 4 (1978), S. 137-141 
    Details
    ISSN: 1573-4978
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The binding of acridine orange and ethidium bromide to rat liver chromatin increases by 30% one hour after partial hepatectomy, returns to the control level by the second hour and increases again by the sixth hour. The changes described were found in investigations carried out on whole cells, on isolated nuclei, and on chromatin preparationin vitro. Increased ligand binding disappears after the treatment of the one-hour chromatin with a 0.3 M NaCl solution, but such a treatment does not change the binding of ligands to chromatin obtained six hours after hepatectomy. The one-hour chromatin is characterized by elongation of distances between individual nucleosomes whereas the two-hour chromatin is the same as in control.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00777513
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  • 5
    Electronic Resource
    Electronic Resource
    Increased susceptibility of activated rat liver chromatin to DNAse I (1979)
    Springer
    Molecular biology reports 5 (1979), S. 215-219 
    Details
    ISSN: 1573-4978
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Rat liver chromatin activated by partial hepatectomy is more susceptible to the action of DNAse I than control chromatin isolated from intact liver. The study on the transfer of chromatin material to the acid-soluble fraction reveals a higher rate of activated chromatin degradation. Activated chromatin shows also an increased capacity for ethidium bromide (EB) binding as estimated from the isotherms of adsorption. The difference in EB binding between activated and control chromatin is abolished after DNAse I treatment. Conditions of mild digestion with DNAse I have been found under which the number of binding sites for EB per nucleotide decreases to almost the same level in activated and non-activated chromatin. The results suggest a preferential degradation of those DNA sequences in activated chromatin that are responsible for the increase in the ligand binding.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00782891
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  • 6
    Electronic Resource
    Electronic Resource
    Chromosome alterations in the karyotype of triticale in comparison with the parental forms (1986)
    Springer
    Theoretical and applied genetics 72 (1986), S. 518-523 
    Details
    ISSN: 1432-2242
    Keywords: Rye ; Triticale ; C-banding ; R genome ; Alterations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary R genome chromosomes were studied in two forms of primary triticales (hexaploid ‘TPG-1/1-78’ and octoploid ‘AD 825’) and in their parent rye forms (Secale cereale L. cv. ‘Kharkovskaya 60’ and ‘VSKhI’, respectively) using the methods of C-banding and morphometric analysis. The size of some heterochromatic segments was shown to alter in the karyotype of triticale. An increase in size was detected approximately in half of all telomeric C-bands; the size of the other C-bands either decreased or did not change. The frequencies of these alterations were 1∶1. The variability in the size of telomeric C-bands in rye chromosomes diminished in both triticales studied. The two triticale forms inherited variants of R genome chromosome polymorphism predominantly with the medium size range of telomeric C-bands. The centromeric C-bands in both triticale forms either enlarged or did not alter. Possible mechanisms responsible for the observed pattern of alterations are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00289534
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  • 7
    Electronic Resource
    Electronic Resource
    Cytogenetic analysis of forms produced by crossing hexaploid triticale with common wheat (1985)
    Springer
    Theoretical and applied genetics 70 (1985), S. 536-541 
    Details
    ISSN: 1432-2242
    Keywords: Triticale ; C-banding ; Substitutions ; Translocations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Hexaploid triticales were crossed with common wheats, and the resultant froms were selected for either triticale (AD 213/5-80) or common wheat (lines 381/80, 391/80, 393/80). The cytogenetic analysis showed that all forms differ in their chromosome composition. Triticale AD 213/5-80 and wheat line 381/80 were stable forms with 2n = 6x = 42. Lines 391/80 and 393/80 were cytologically unstable. In triticale AD 213/5-80, a 2R (2D) chromosome substitution was found. Each of the three wheat lines had a chromosome formed by the translocation of the short arm of IR into the long arm of the IB chromosome. In line 381/80, this chromosome seems to be inherited from the ‘Kavkaz’ wheat variety. In lines 391/80 and 393/80, this chromosome apparently formed de novo since the parent forms did not have it. The karyotype of line 381/80 was found to contain rye chromosomes 4R/7R, 5R and 7R/4R. About 15% of the cells in line 391/80 contained an isochromosome for the 5R short arm and also a chromosome which arose from the translocation of the long arms of the 5D and 5R chromosomes. About one-third of the cells in the common wheat line 393/80 contained the 5R chromosome. This chromosome was normal or rearranged. Practical applications of the C-banding technique in the breeding of triticale is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00305987
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  • 8
    Electronic Resource
    Electronic Resource
    Chromosomal alterations in the karyotype of triticale in comparison with the parental forms (1986)
    Springer
    Theoretical and applied genetics 73 (1986), S. 66-71 
    Details
    ISSN: 1432-2242
    Keywords: Triticale ; Ancestor forms ; C-banding
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Wheat chromosomes of the primary winter hexaploid and octoploid triticales and of the parental durum and common wheat varieties were studied using morphometric analysis. The size of some heterochromatic segments was shown to change in triticale. Telomeric and intercalary C-bands both increased and decreased in size whereas centromeric bands only increased. The size variability of C-bands in triticale B-genome chromosomes decreased in most of the cases and increased only for several specific C-bands. The C-bands of homologous B-genome chromosomes changed in the same direction in both triticale forms. The changes in size of the C-bands found in R-genome chromosomes detected earlier in these triticale forms (Badaeva et al. 1986) were shown to coincide in their pattern with the size changes of C-bands in homeological B-genome chromosomes. Our data are indicative of regular, directed chromosomal changes in the triticale karyotype.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00273720
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  • 9
    Electronic Resource
    Electronic Resource
    Cytogenetic Analysis of Hybrids Resistant to Yellow Rust and Powdery Mildew Obtained by Crossing Common Wheat (Triticum aestivum L., AABBDD) with Wheats of the Timopheevi Group (AtAtGG) (2000)
    Springer
    Russian journal of genetics 36 (2000), S. 1401-1410 
    Details
    ISSN: 1608-3369
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The karyotypes of 47 hybrid lines obtained from crosses of common wheat Triticum aestivum L. (cv. Rodina and line 353) with Triticum timopheevii(Zhuk.) Zhuk. (A t A t GG) and related species T. militinae Zhuk. et Migusch. (A t A t GG) and T. kiharae Dorof. et Migusch. (A t A t GGD sq D sq) were analyzed by C-banding. Most lines were resistant to yellow rust and powdery mildew. The introgression of alien genetic material to the common wheat genome was realized via substitutions of complete A +-,G-, and D-genome chromosomes, chromosome arms, or their fragments. The pattern of chromosome substitutions in resistant lines differed from that in introgressive hybrids selected for other traits. Substitutions of chromosomes 6G, 2At, 2G, and 5G were revealed in 31, 23, 18, and 13 lines, respectively. Substitutions of chromosomes 4G, 4At, and 6At were not observed. In 15 lines, a 5BS.5BL-5GL translocation was identified. High frequency of substitutions of chromosomes 2At, 2G, 5G, and 6G indicate that they may carry the resistance genes and that they are closely related to the respective homoeologous chromosomes of common wheat that determines their high compensation ability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009019323942
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  • 10
    Electronic Resource
    Electronic Resource
    Properties of chromatin of peripheral blood lymphocytes of women with threatened abortion (1984)
    Springer
    Bulletin of experimental biology and medicine 97 (1984), S. 207-209 
    Details
    ISSN: 1573-8221
    Keywords: chromatin ; lymphocytes ; pregnancy in women
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00804101
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