ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Collagen (Col) and chitosan (Chi) are both natural polymers and have received extensiveinvestigation in recent years in the field of tissue engineering, but there are few reports on theintroduction of hydroxyapatite (HA) into the Col-Ch system. In this study, based on the miscibilityof these two polymers under proper condition, hydroxyapatite (HA) was synthesis in the Col-Chisystem by in-situ co-precipitate method to give rise to a novel nanocomposite. The structuralcharacterization of such Col-Ch-HA nano-materials was carried out by using FT-IR, XRD, SEMand TGA analyses with main components and Col-Chi samples used for comparison. It was foundthat there exist interactions between Col and Chi molecules. The nucleation and growth of inorganicphase occurs in the Col-Chi system and final products are uniform dispersion of nano-sized HA inthe Col-Chi network without obvious phase separation. This novel nanocomposite would be apromising material for bone tissue engineering
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/52/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.330-332.415.pdf
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