ISSN:
1573-8221
Keywords:
acylprolyldipeptide
;
GVS-111
;
pharmacokinetics
;
blood-brain barrier permeability
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Pharmacokinetics of GVS-111, a new acylprolyldipeptide with nootropic properties and its penetration across the blood-brain barrier were studied in rats using HPLC. It was found that the dipeptide is absorbed in the gastrointestinal tract, enters the circulation, and penetrates through the blood-brain barrier in an umodified state.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02439270
Permalink