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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Journal of cancer research and clinical oncology 77 (1972), S. 279-291 
    ISSN: 1432-1335
    Schlagwort(e): Lung mouse tumors ; Chemical carcinogen ; Ultrastructure ; Pneumocyte II ; Crystalline inclusions ; Interstitial fibrosis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Summary The pulmonary tumours induced in Swiss mice by NMUR seem to be constituted for the most part by cells closely related to the granular pneumocytes (pneumocytes II ou B). Other rarer cells, of epithelial bronchiolar aspect, may take part in the proliferation. The ultrastructural study of tumoral cells suggest that their secretory functions are disturbed. The origin of the crystalline intratumoral structures is discussed, as well as their possible relationship with the production of surfactant. The peritumoral areas are characterized by a dense interstitial flbrosis in which the collagen fibers are associated with an elastoid substance.
    Notizen: Resumé Les tumeurs pulmonaires induites chez la souris swiss par le NMUR apparaissent essentiellement constituées de cellules apparentées aux pneumocytes granuleux (pneumocytes II ou B). D'autres cellules plus rares, de morphologie épithéliale bronchiolaire peuvent participer á la prolifération. L'étude ultrastructurale des cellules tumorales suggère que leurs fonctions secrétoires sont perturbées. Le mode de formation des structures cristallins intratumorales est discuté, ainsi que leur rapport éventuel avec la production du surfactant. Les territoires péri-tumoraux sont caractérisés par une fibrose interstitielle dense où les fibres de collagène sont associées à uns substance élastoïde.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Calcified tissue international 9 (1972), S. 238-242 
    ISSN: 1432-0827
    Schlagwort(e): Dentine ; Ultrastructure ; Tubule ; Tooth
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin , Physik
    Beschreibung / Inhaltsverzeichnis: Résumé L'étude ultrastructurale de la dentine humaine périphérique, de couronnes dentaires de sujets âgés de 11 à 75 ans, a montré trois aspects principaux du contenu des canalicules en coupe transversale. Il s'agit de canalicules apparemment vides, de canalicules contenant un matériel organique annulaire et, enfin, de canalicules totalement remplis d'un matériel organique d'aspect granulaire ou hyalin. Aucune terminaison nerveuse n'est visible à ce niveau.
    Kurzfassung: Zusammenfassung Die ultrastrukturelle Untersuchung von peripherem menschlichem Zahnkronendentin bei Patienten im Alter von 11–75 Jahren hat drei Hauptaspekte des Inhaltes der Dentintubuli gezeigt. Sie bestehen bei transversalen Schnitten aus toten Gängen sowie beim Lumen der Tubuli entweder aus ringförmigen oder ganzausfüllenden Ablagerungen. Im äußeren Dentin wurden keine Nervenendigungen beobachtet.
    Notizen: Abstract An ultrastructural study of peripheral human coronal dentin in patients aged 11 to 75 years, has shown main aspects of the dentinal tubular content. In transverse sections, they consist of dead tracts and annular or solid content to the tubular lumen. No nerve endings were observed in the outer dentin.
    Materialart: Digitale Medien
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Acta neuropathologica 21 (1972), S. 68-75 
    ISSN: 1432-0533
    Schlagwort(e): Myelinated Nerve ; Venom ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The fine structure of right sciatic nerves of Swiss white mice was studied after being exposed to a venom solution ofAgkistrodon contortrix laticinctus (broad-banded copperhead) and to 0.9% NaCl solutions for periods of 1, 2 or 3 h. There was some “Wallerian-like” degeneration in all groups of nerves in the experiment. Additional neuropathological changes were noted in the nerves exposed to venom solutions. The connective tissue was affected most severely, while the basal lamina was unaffected. Schwann cells were vacuolated, and in the most extreme case, a type of myelin splitting occurred which was considered as a “demyelinative” effect. The results were compared to those of Martin and Rosenberg (1968) [15] on studies of the giant squid axon. References to additional fine structural studies of various other neuropathies were given.
    Materialart: Digitale Medien
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Acta neuropathologica 21 (1972), S. 239-252 
    ISSN: 1432-0533
    Schlagwort(e): Ultrastructure ; Myotendon ; Zebra-Bodies (ladder-like structure) ; Rods
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The ultrastructure of the adult and foetal human myotendon is described. At the myotendon the muscle fibre is surrounded by plasma and basement membranes which are never penetrated by the adjacent collagen fibrils of the tendon. Increased thickness and electron density of the plasma membrane and the myofilaments which merge with it occur at the myotendon and this electron dense zone corresponds to the terminal Z-line of the final sarcomere of the myofibril. In the adult the muscle fibre near the myotendon may contain nemaline rods and zebra-bodies. The tendon in the foetus shows much more activity of the fibroblasts than in the normal adult. The collagen fibrils of the early foetus are thinner in diameter than at later stages of development. The union of the tendon with cartilage is illustrated.
    Materialart: Digitale Medien
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  • 5
    Digitale Medien
    Digitale Medien
    Springer
    Calcified tissue international 10 (1972), S. 38-48 
    ISSN: 1432-0827
    Schlagwort(e): Bivalve ; Molluse ; Shell ; Carbonates ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin , Physik
    Beschreibung / Inhaltsverzeichnis: Résumé La technique du bombardement à l'aide d'ion d'argon est utilisée pour réduire l'épaisseur de la coquille de carbonate de calcium des bivalvesMytilus etMercenaria pour examen au microscope électronique par transmission et en diffraction électronique; une comparaison est réalisée à l'aide de répliques simples, servant de témoins. Les résultats obtenus confirment les études antérieures de répliques et de microscopie par balayage. De plus, une structure “aérée” est mise en évidence dans la coquille des aragonites, et surtout dans le nacre deMytilus. Cette structure est interprêtée comme un artefact induit par la chaleur, formé par l'inclusion d'eau et de matériel organique, interprétation qui concorde avec les études chimiques et de microscopie électronique.
    Kurzfassung: Zusammenfassung Die Beschießung mit Argonionen wurde angewendet, um die Dicke von Calciumcarbonat-Schalen der zweischaligen MuschelnMytilus undMercenaria zu reduzieren. Diese Technik erlaubte die Ausführung von Transmissions-Elektronenmikroskopie und Elektronendiffraktion, wobei gleiche Proben nach einer bereits bestehenden Methode vorbereitet und als Kontrollen herangezogen wurden. Es wurden zusätzliche Resultate zu den Muschelstruktur-studien erhalten, welche früher publizierte Arbeiten unterstützen, die mit der Abklatschmethode und der Raster-Elektronenmikroskopie ausgeführt worden waren. Zusätzlich wurde eine „schaumartige” Struktur der Muschelaragoniten, besonders im Perlmutter vonMytilus, beobachtet. Da es sich um ein durch Hitze verursachtes Artefakt handelt, wird diese Struktur als Einschlüsse von Wasser und organischem Material interpretiert, was den Befunden von verschiedenen veröffentlichten chemischen und elektronenmikroskopischen Arbeiten entspricht.
    Notizen: Abstract Use is made of the argon ion-bombardment technique to reduce the thickness of calcium carbonate shells of the bivalvesMytilus andMercenaria for transmission electron microscopy and electron diffraction, with comparison of single-stage replicas of similar specimens serving as controls. As an additional approach to shell structure studies, it gives results which support earlier published work with both replicas and scanning microscopy. In addition, a “frothy” structure is detected in the shell aragonites, especially inMytilus nacre. As a heat-induced artifact, it is interpreted as representing trapped water and organic material inclusions, an interpretation consistent with several published chemical and electron microscope studies.
    Materialart: Digitale Medien
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Cell & tissue research 128 (1972), S. 538-554 
    ISSN: 1432-0878
    Schlagwort(e): Arteries ; DOCA hypertension ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The ultrastructure of the unconstricted superficial epigastric and femoral arteries is described in normal rats and in animals with hypertension induced by unilateral nephrectomy, by subcutaneous injections of desoxycorticosterone acetate and drinking of 1% NaCl. The femoral artery showed by far the greater response to the DOCA-saline treatment. In both vessels, the smooth-muscle cells changed from the normal spindle shape to a blunt ended outline with numerous pinocytotic vesicles and prolific collagen production. With long term hypertension, particularly in the femoral artery, the smooth-muscle cell profiles became very irregular. Hypertrophy of the organelles of the smooth-muscle cells was associated with an increase in the intercellular material which gradually changed from a mainly collagenous character to mainly vesicular. Lysosomal activity indicated cell disintegration. White blood cells adhere to the endothelium in hypertensive rats and there was an increase in subendothelial material. The number of intimal smooth-muscle cells increased noticeably in the femoral artery. In both arteries, the adventitial fibroblasts hypertrophied in hypertensive rats. In animals with an elevated blood pressure the morphological response was observed as early as 4 to 7 days after initiation of treatment.
    Materialart: Digitale Medien
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  • 7
    Digitale Medien
    Digitale Medien
    Springer
    Cell & tissue research 135 (1972), S. 473-482 
    ISSN: 1432-0878
    Schlagwort(e): Neurosecretory nerves ; Glial and pigment cells ; Neural sheath ; Gastropods ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The fine structure of neurosecretory nerves and endings associated with the sheath of the infraesophageal ganglion ofHelix aspersa is described. The sheath is a neurohemal organ whose vascularized stroma receives both monoaminergic and peptidergic endings. The latter occur along the surface of the nerves or scattered within the stroma. They include a complex population of vesicular profiles. The granular vesicles (1300–3000 Å in diameter) exhibit structural modifications that may be related to the intra-axonal release of their neurohormones. The agranular vesicles (500–2000 Å in diameter) occur in large numbers and lie mostly adjacent to the axon surface. Synaptoid specializations seem to represent active sites for the extracellular discharge of neurosecretory material. The monoaminergic endings so far studied lack synaptoid specializations and contain small granular (800–1300 Å in diameter) and agranular (700 Å in diameter) vesicles. Two kinds of non-neural cells are associated with the nerves: glial cells and melanocytes.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 8
    ISSN: 1432-0878
    Schlagwort(e): Rat pituitary gland ; Ultrastructure ; Granule extrusion ; LH-releasing hormone
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary In order to observe the ultrastructural aspects of granule extrusion from gonadotrophs, the authors injected pure, natural porcine LH-releasing hormone (LH-RH) into persistent-estrous (PE) rats. Clear-cut extrusions of secretory granules appeared from LH-gonadotrophs 2.5, 5 and 15 minutes after the injection. Massive extrusion was observed at 15 minutes. Serum LH and FSH were also estimated by radioimmunoassay on blood samples taken at the same times after the injections. LH was increased in the blood sera after the injection of LH-RH, but serum FSH was not significantly different among the various treated rats. The rise in serum LH after LH-RH injection was well correlated with the ultrastructural phenomenon of granule extrusion from LH-gonadotrophs.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 9
    Digitale Medien
    Digitale Medien
    Springer
    Cell & tissue research 134 (1972), S. 255-271 
    ISSN: 1432-0878
    Schlagwort(e): Hepatopancreas ; Limulus ; Gap junctions ; Calcium spherules ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The ultrastructure of the hepatopancreas and associated tissues of Limulus is described. All hepatopancreatic tubules contain L- and D-cells. L-cells exhibit apical pinocytosis and contain many different types of inclusions, including lipid containing calcium spherules of unique structure. They also produce a complex secretory product released by apocrine secretion. D-cells contain much rough endoplasmic reticulum, and show other evidence of active protein synthesis. They produce a single type of secretory granule released by merocrine activity. The appearance of L- and D-cells in tubules of various sizes and in fed and starved animals is described. Both cell types may produce digestive enzymes and absorb and transport nutrients to the hemolymph, but neither serves as a major storage site. Storage is an important function of the intertubular R-cells. The appearance of R-cells in fed and starved animals is described. A previously undescribed hemocyte is reported, as are apparent gap junctions between L- and R-cells. A structural and functional comparison of these glands with those of other arthropods is presented.
    Materialart: Digitale Medien
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  • 10
    Digitale Medien
    Digitale Medien
    Springer
    Cell & tissue research 123 (1972), S. 458-469 
    ISSN: 1432-0878
    Schlagwort(e): Photoreceptor ; Bryozoa ; Larva ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The pigmented spots of bryozoan larvae have often been implicated in photoreception due to their preferential occurrence in larvae with positive phototactic behavior. Results of light and electron microscopic studies of Bugula neritina show that the larvae possess two spots, each with a basal sensory cell situated at the base of a pit-like depression. The embedment of the pit and its basal cell in a pad of subepidermal pigment cells allows for directional illumination. The basal sensory cell produces a ball-like mass of non-motile cilia. The configuration of the axoneme is typical of kinocilia and unlike the arrangement previously described for ciliary photoreceptors. Elaboration of receptor organelle membrane surface area is accomplished uniquely by multiple cilia oriented so that large portions of each cilium lie perpendicular to the direction of incident light. The pigmented spot directly contacts the underlying equatorial nerve ring which also connects with the major larval locomotor organ. The pigmented spots of B. neritina are the only potential photoreceptor structures which have been studied by electron microscopy in the three lophophorate phyla. The use of ciliary membranes as the potential photoreceptor organelle allies the bryozoan pigmented spot with the ciliary type photoreceptor which occurs most prevalently in deuterostome animals.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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