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  • 1
    Electronic Resource
    Electronic Resource
    Polarized electronic absorption spectra for potassium tetrabromoplatinate(II) dihydrate. Spectral effects of a platinum(IV) component (1978)
    s.l. : American Chemical Society
    Inorganic chemistry 17 (1978), S. 2302-2307 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic50186a058
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Comparative kinetic studies of cytochromes c in reactions with mitochondrial cytochrome c oxidase and reductase (1978)
    s.l. : American Chemical Society
    Biochemistry 17 (1978), S. 1015-1027 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00599a012
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Plakortin, an antibiotic from Plakortis halichondrioides (1978)
    s.l. : American Chemical Society
    The @journal of organic chemistry 43 (1978), S. 3454-3457 
    Details
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jo00412a006
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    STUDIES ON THE REGULATION OF GABA SYNTHESIS: SUBSTRATE-PROMOTED DISSOCIATION OF PYRIDOXAL-5′-PHOSPHATE FROM GAD (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 30 (1978), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The association between glutamate decarboxylase (GAD) and its cofactor, pyridoxal-5′-phos-phate (pyridoxal-P), was studied using 20,0000 supernatant of rat brain. In this preparation GAD required added pyridoxal-P to maintain a linear reaction rate beyond 5 min of incubation. Following exhaustive dialysis the enzyme was more than 83% saturated with cofactor indicating that the cofactor was tightly bound to the enzyme. When incubations were performed in the presence of glutamate and without added pyridoxal-P there was a progressive inactivation of the enzyme which was dependent on the glutamate concentration. This lost activity was almost completely recovered by addition of pyridoxal-P to the dialyzed glutamate-inactivated enzyme. The results suggest that glutamate inactivates GAD by promoting the dissociation of pyridoxal-P from the enzyme thereby producing inactive apoen-zyme which can be reactivated by combining with available pyridoxal-P. This interpretation is supported by the finding that progress curves for the reaction were accurately described over a 30 min incubation period and 10-fold glutamate concentration range by an integrated rate equation which takes the glutamate-promoted dissociation of cofactor into account. The progressive inactivation could not be attributed to denaturation of the enzyme, impurities in the substrate, effects of pH, depletion of substrate, protein concentration, sulfhydryl reagents or product inhibition. The results presented here also show that certain precautions must be adopted to accurately measure GAD activity in the absence of added pyridoxal-P as has been widely done in studies of drug action. Specifically, measurements must be made at short times of incubation and low concentrations of glutamate to minimize the glutamate-promoted inactivation of the enzyme.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1978.tb06538.x
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  • 5
    Electronic Resource
    Electronic Resource
    STUDIES ON THE REGULATION OF GABA SYNTHESIS: THE INTERACTION OF ADENINE NUCLEOTIDES AND GLUTAMATE WITH BRAIN GLUTAMATE DECARBOXYLASE (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 30 (1978), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The effects of adenine nucleotides and glutamate on glutamate decarboxylase were studied in a dialyzed, high-speed supernatant of rat brain. When incubated with 10 μm-pyridoxal-P the enzyme was strongly inhibited by ATP, ADP and their Mg2+ complexes at concentrations which were well below tissue levels. The enzyme was not significantly inhibited by 15 mm-AMP or by 100 μM-3′-5’cyclic AMP or 3′-5’cyclic GMP. Inhibition by the nucleotides cannot be described in conventional steady-state kinetic terms. Addition of ATP in the presence of pyridoxal-P resulted in a slow, progressive decrease in the reaction rate which was similar to the inactivation observed when the enzyme was incubated in the absence of pyridoxal-P. The progressive inactivation in the presence of ATP was minimal at concentrations of glutamate which were well below Km and became much more pronounced at higher glutamate concentrations. Addition of suprasaturating amounts of pyridoxal-P late in the incubation when the enzyme was almost completely inactivated resulted in an immediate and complete reactivation of the enzyme. Inhibition by ATP could be prevented by addition of saturating amounts of pyridoxal-P at the start of the reaction and was also relieved by addition of potassium phosphate buffer. The results suggest that inhibition by the nucleotides involves the prior formation of the inactive apoenzyme which results from the glutamate-promoted dissociation of pyridoxal-P. In the absence of the nucleotides, the enzyme is normally reactivated by the added pyridoxal-P. The nucleotides act to block this reassociation of pyridoxal-P with the apoenzyme thereby producing a progressive inactivation of the enzyme. The implications of these results for the regulation of GABA synthesis are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1978.tb06539.x
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  • 6
    Electronic Resource
    Electronic Resource
    On the time required for reference count management in retention block-structured languages. Part 2 (1978)
    Springer
    International journal of parallel programming 7 (1978), S. 91-119 
    Details
    ISSN: 1573-7640
    Keywords: Block-structured languages ; retention vs. deletion ; contour model ; stack model ; reference counts ; lifetime checks ; time estimates
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract In this paper, two implementations of generalized block-structured languages are presented and compared for time requirements. One implementation, the Lifetime Stack Model, implements the deletion strategy with lifetime checks; the other, the Partial Reference Count Contour Machine, implements the retention strategy. For a large subset of the lifetime well-stacking programs, those that run correctly on the first model, the two models are shown to require nearly the same order of magnitude of time. The use of full label values is shown to have a detrimental effect on the time efficiency of the latter model. Part 1, in Volume 7, Number 1, of this journal, gives a general description of the machines, some of their definitions, and proof of the results. Part 2, in this issue, serves as an appendix to Part 1 and contains most of the formal definitions of the machines.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00975882
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  • 7
    Electronic Resource
    Electronic Resource
    Time required for reference count management in retention block-structured languages. Part 1 (1978)
    Springer
    International journal of parallel programming 7 (1978), S. 11-64 
    Details
    ISSN: 1573-7640
    Keywords: Block-structured languages ; retention vs. deletion ; contour model ; stack model ; reference counts ; lifetime checks ; time estimates
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract In this paper, two implementations of generalized block-structured languages are presented and their time requirements compared. One implementation, the lifetime stack model (LSM), implements the deletion strategy with lifetime checks; the other, the partial reference count contour machine (PRCCM), implements the retention strategy. For a large subset of the lifetime well-stacking programs, which are precisely those that run correctly on the first model, the two models are shown to require nearly the same order of magnitude of time. The use of full-label values is shown to have a detrimental effect on the time efficiency of the latter model. Part 1, in this issue, gives a general description of the machines and part of their definitions, and proves the results. Part 2, in the next issue, serving as an appendix to Part 1, contains most of the formal definitions of the machines.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00991939
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  • 8
    Electronic Resource
    Electronic Resource
    Littoral zone fish communities of two Florida lakes and a comparison with Michigan lakes (1978)
    Springer
    Environmental biology of fishes 3 (1978), S. 163-172 
    Details
    ISSN: 1573-5133
    Keywords: Fish ; Habitat structure ; Species composition and abundance ; Ecological segregation ; Regional comparisons ; Temperate lakes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis The abundance and habitat distribution of littoral zone fishes in two small southern Florida lakes were quantified by underwater censuses. The bluegill (Lepomis macrochirus) and large-mouth bass (Micropterus salmoides) accounted for 75–80% of community biomass in both lakes; important coexisting species were predominantly benthic feeders in Lake Sirena and planktivores in Lake Annie. All species were largely confined to areas of macrovegetation which extended to a depth of 4 m in Lake Annie but only to 1.2 m in Lake Sirena. The differences in community structure were related to differences in habitat and also variation in water levels and benthic production. A comparison of community composition with that of small Michigan lakes indicated that similar numbers of species coexist in the littoral zones, despite a three-fold difference in the size of regional species pools. The majority of families and about 50% of the species were common to lakes in both regions; in addition a number of ecological analogues were noted. A major difference was that the small inshore species were members of the Cyprinodontiformes in Florida and Cyprinidae in Michigan. Together the largemouth bass and bluegill comprise similar community proportions in the two regions as do other major feeding groups. Lakes in the two regions that are similar in amount and distribution of vegetation exhibit greater similarity in fish communities than those within regions that differ in littoral vegetation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691940
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  • 9
    Electronic Resource
    Electronic Resource
    Some function classes closed under infimal convolution (1978)
    Springer
    Journal of optimization theory and applications 25 (1978), S. 579-584 
    Details
    ISSN: 1573-2878
    Keywords: Level sets ; connected level sets ; infimal convolution ; local-global property
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract It is shown that the following classes of functionsf, each defined on some subsetD of a fixed Hausdorff topological vector spaceE, are closed under the binary operation of infimal convolution: (a) the class of functionsf:D→[−∞, ∞) having connectedstrict lower level sets; (b) the class of functionsf:D→ℝ having compact connected lower level sets; and (c) the class of functionsf:D→ℝ having compact lower level sets and for which every local minimizer is global. In (a),E need not be Hausdorff; while in (a) and (b), the word “connected” may be replaced by the word “path-connected.”
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00933523
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  • 10
    Electronic Resource
    Electronic Resource
    The effects of stressful arousal on conjugate lateral eye movement (1978)
    Springer
    Motivation and emotion 2 (1978), S. 345-353 
    Details
    ISSN: 1573-6644
    Source: Springer Online Journal Archives 1860-2000
    Topics: Psychology
    Notes: Abstract This study investigated the relationship between stressful arousal and conjugate lateral eye movement tendencies in right-handed males. Sixty subjects were asked both neutral and mildly emotional questions after watching either a stressful industrial accident movie or a bland control film. Subjects had been previously classified as either right-movers, left-movers, or bidirectionals on the basis of their responses in a prefilm interview. A statistically significant interaction between dominant direction and film condition was found on right eye movement. Subjects classified as right-movers displayed increased right eye movement preferences under the stress film, compared to the neutral film condition. This effect was seen with neutral, but not mildly emotional, questions. Results were interpreted within an elaborated brain asymmetry model of conjugate lateral eye movement, in which stressful arousal is assumed to increase subjects' reliance on characteristic, neurologically based ways of dealing with stimuli. Implications for theory and research on brain-behavior relationships in ego-defensive styles are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00993329
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