Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Antiallergic activity of loratadine, a non-sedating antihistamine (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 42 (1987), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Loratadine is a new non-sedating antihistamine. The present studies compared loratadine and terfenadine, another non-sedating antihistamine, for their ability to inhibit the bronchial response to histamine and other autacoids which have been implicated as contributing to the symptoms of an allergic reaction. In addition, the two antihistamines were evaluated in models of immunologically mediated allergic reactions. Loratadine is a more potent inhibitor of histamine-induced bronchospasm in guinea pigs than is terfenadine. Both antihistamines exhibit marked antiserotonin activity at doses 10 times their antihistamine ED50 values. In contrast, loratadine and terfenadine produce little or no inhibition of the bronchial responses to methacholine, leukotriene C4 or platelet-activating factor. An allergic bronchospasm in guinea pigs is inhibited by loratadine (ED50= 0.40 mg/kg, p.o.) and terfenadine (ED50= 1.7 mg/kg, p.o.). The bronchospasm associated with allergic anaphylaxis in rats is significantly inhibited by 10 mg/kg, p.o. loratadine and 30 mg/kg, p.o. terfenadine. Loratadine exhibits antiallergy activity in vitro. At micromolar concentrations, loratadine inhibits the release of histamine from Con A and A23187-stimulated rat peritoneal mast cells and the release of histamine and leukotrine C4 from a Con A-stimulated cloned murine mast cell line
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.1987.tb02188.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    The importance of palpation in food selection by a polyphagous grasshopper (Orthoptera: Acrididae) (1993)
    Springer
    Journal of insect behavior 6 (1993), S. 79-91 
    Details
    ISSN: 1572-8889
    Keywords: associative learning ; grasshopper ; palpation ; plant surface
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The behavioral responses of final-instar nymphs of Schistocerca americanato a variety of acceptable and unacceptable plants were recorded. Palpation occurred on all plants and the palps are involved in both acceptance and rejection. On most unacceptable plants, rejection was at first dependent on biting the leaf, but subsequently on Lantana, Machaeranthera, Moms,and Physalis,rejection often occurred after palpation of the surface alone. This is consistent with the suggestion that associative learning occurs. This response did not wane even when the insects had been without food for over 2 h. There was also some evidence of an innate response to the surface characteristics of Physalis.The features of the surfaces that produced these responses were not determined.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01049149
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Cerebral intraventricular haemorrhage in a young adult (1993)
    Springer
    International journal of legal medicine 105 (1993), S. 243-245 
    Details
    ISSN: 1437-1596
    Keywords: Intraventricular haemorrhage ; Head injury ; Traumatic subarachnoid haemorrhage ; Intraventrikuläre Blutung ; Kopftrauma ; Traumatische Subarachnoidalblutung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Der Fall eines 26 Jahre alten Mannes wird beschrieben, welcher nach einer Episode von Traumen eine tödliche intraventrikuläre Hirnblutung erlitt. Bei der Obduktion wurde nach dem ersten Eindruck eine traumatische Subarachnoidalblutung vermutet, und die anfängliche Untersuchung war daher auf die Strukturen des Halses und auf die Vertebralarterien gerichtet, jedoch mit negativen Resultaten. Die Sektion des fixierten Gehirns zeigte eine massive intraventrikuläre Blutung mit sekundärer Beteiligung des Subarachnoidalraums und Ausbreitung in das Hirnparenchym. Keine Blutungsquellen oder natürliche Erkrankungen der Hirngefäße konnten gefunden werden. Die praktischen Aspekte der Diagnose und der vorsichtige Ansatz, welcher notwendig ist, um Subarachnoidalblutungen zu interpretieren, werden betont. Die Bedeutung der intraventrikulären Blutung nach Trauma ist mit der Einführung der Computertomographie offensichtlicher geworden. Die Implikationen dieses und ähnlicher Fälle werden bedacht.
    Notes: Summary A case of a 26-year-old man who suffered a fatal intraventricular cerebral haemorrhage following an episode of trauma is described. The initial appearance at necropsy suggested a traumatic subarachnoid haemorrhage and initial investigation was directed towards the anterior neck structures and the vertebral arteries with negative results. Dissection of the fixed brain showed a massive intraventricular bleed with secondary involvement of the subarachnoid space and dissection into the cerebral parenchyma. No bleeding points or natural disease of the cerebral vessels could be identified. The practical aspects of diagnosis and the cautious approach necessary in interpreting subarachnoid bleeding is emphasised. The significance of intraventricular haemorrhage following trauma has become more apparent with the advent of computed tomographic scanning. The implications for this and similar cases are considered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01642802
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    The effect of oximes on the dihydropyridine-sensitive Ca current of isolated guinea-pig ventricular myocytes (1993)
    Springer
    Pflügers Archiv 422 (1993), S. 325-331 
    Details
    ISSN: 1432-2013
    Keywords: Myocyte ; Voltage clamp ; Ionic currents ; Oximes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Exposure of isolated guinea-pig ventricular myocytes to the uncharged oximes 2,3 butanedionemonoxine (BDM) and norPAM (but not by the charged PAM) results in a dose-dependent reduction of the duration of the action potential. The nifedipine-sensitive Ca current is fully inhibited by BDM (IC505.8±0.4 mM) and nor PAM but is little affected by PAM. This inhibition is unaltered by the presence of BAY K 8644 but is antagonized by isoprenaline. The effect of isoprenaline is more pronounced when the solution in the patch pipette contains the non-hydrolysable analogue of adenosine 5′-triphosphate, ATPγS (the IC50 is increased to 44.0±5.2 mM). A hastening of the inactivation of the L-type Ca current persists when either 10 mM 1,2-bis(2-aminophenoxy)-ethane-N, N, N′, N-tetraacetic acid (BAPTA) or 3 mM ATPγS is present in the pipette solution or when BAY K 8644 or isoprenaline are present in the bathing fluid. These results suggest that the inhibition of the Ca current is due to the phosphatase-like activity of the oximes but differs in some respects from previous work where a reduced level of phosphorylation is achieved by the introduction of protein kinase inhibitors or protein phosphatases into the sarcoplasm in guinea-pig myocytes. These differences could be explained if Ca channel availability is regulated by at least two sites of cAMP-dependent phosphorylation with oximes able to rapidly dephosphorylate both sites, while one of these sites is not readily dephosphorylated by the endogenous phosphatases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00374287
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Secretion and membrane recycling in plant cells: novel intermediary structures visualized in ultrarapidly frozen sycamore and carrot suspension-culture cells (1987)
    Springer
    Planta 171 (1987), S. 43-57 
    Details
    ISSN: 1432-2048
    Keywords: Acer ; Daucus ; Cell culture ; Freeze-fracture (rapid freezing) ; Membrane recycling ; Plasma membrane ; Secretion (vesicle-mediated)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Freeze-fracture electron microscopy of propane-jet-frozen samples has been employed to investigate vesicle-mediated secretion and membrane recycling events in carrot (Daucus carota L.) and sycamore maple (Acer pseudoplatanus L.) suspension-culture cells. Stabilization of the cells by means of ultrarapid freezing has enabled us to preserve the cells in a turgid state and to visualize new intermediate membrane configurations related to these events. Indeed, many of the observed membrane configurations, such as flattened membrane vesicles with slit-shaped membrane fusion sites and horseshoe-shaped membrane infoldings, appear to result from the action of turgor forces on the plasma membrane. Individual cells exhibited great variations in numbers and types of membrane configurations postulated to be related to secretion and membrane-recycling events. In the majority of cells, the different membrane profiles displayed a patchy distribution, and within each patch the membrane configurations tended to be of the same stage. This result indicates that secretory events are triggered in domains measuring from 0.1 to about 10 μm in diameter. Based on an extensive analysis of the different membrane configurations seen in our samples, we have formulated the following model of vesicle-mediated secretion in plant cells: Fusion of a secretory vesicle with the plasma membrane leads to the formation of a single, narrow-necked pore that increases in diameter up to about 60 nm. During discharge, the vesicle is flattened, forming a disc-shaped structure perpendicular to the plane of the plasma membrane. As the vesicle is flattened, the pore is converted to a slit, the maximum length of which coincides with the diameter of the flattened vesicle. The flattened vesicle then tips over and concomitantly the plasma-membrane slit becomes curved into a horseshoe-shaped configuration as it extends along the outer margins of the tipped-over vesicle. Some coated pits are present interspersed between the above-mentioned structures, but their numbers appear insufficient to account for an exclusively endocytotic mechanism of membrane recycling. Instead, our micrographs are more consistent with a mixed mode of recycling of membrane components to the cortical endoplamic reticulum and to Golgi cisternae that involves both internalization of membrane by endocytosis and of individual lippid molecules by unknown mechanisms (lipid exchange proteins?). To this end, overall flattening out of the horseshoe-shaped membrane infoldings is accompanied by a retraction and reduction in size of their central, tongue-like structure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00395066
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Search for superdeformation in180Os (1987)
    Springer
    The European physical journal 328 (1987), S. 379-380 
    Details
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Two-dimensional γ-ray energy correlations have been measured at high spins in1800s with the TESSA2 spectrometer. The Eγ − Eγcorrelation matrix displays ridges characteristic of rotational bands with different energy separations of 96± and 72± keV for the energy regions of 660 to 840 keV and 975 to 1170 keV, respectively. The separation of these ridges remains constant in both energy regions. The dynamical moments of inertia are θ(2) =83±3 and 111±5 ħ2/MeV, respectively. The latter value suggests superdeformation in1800s with an axis ratio c/a=1.76 (β2 ≅0.64) at high spins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01290507
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Miticide bioassays with spider mites (Acari: Tetranychidae): effect of test method, exposure period and mortality criterion on the precision of response estimates (1993)
    Springer
    Experimental and applied acarology 17 (1993), S. 695-708 
    Details
    ISSN: 1572-9702
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Six different bioassay methods were evaluated using propargite (Omite 30% wettable powder (WP) and fenbutatin oxide (Torque 50% (WP) and 55% suspension concentrate (SC)) with twospotted spider mite, Tetranychus uriticae Koch (TSM) and European red mite, Panonychus ulmi Koch (ERM) to document their utility and precision for estimating median lethal concentrations (LC). For each method, two post-treatment exposure periods and mortality criteria were used. Post-treatment exposure period and mortality criterion had a significant influence on the precision of LC50 estimates for all tested miticides with all bioassays methods. Twenty four hour (h) post-treatment exposure was found to be the most suitable for the slide dip and Petri dish methods while 48h was the most appropriate for leaf disc methods. Scoring moribund mites as dead was the most satisfactory criterion for ensuring that biossays were as simple and precise as possible. The Petri dish residue-Potter tower method (PDR-PT) estimated the responses of TSM and ERM to propargite with high precision. The same method was not as precise for fenbutatin oxide formulations. Because significant mite run-off occurred with the leaf disc methods, their precision was not fully established. The slide dip method gave less precise estimates of LC50 values for propargite (WP) and fenbutatin oxide (WP), while the same method gave more precise LC50 estimates for fenbutatin oxide (SC) than the PDR-PT method. The toxicity of candidate miticides was found to be method-and species-dependent.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00058509
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Functional response of pacific damsel bug,Nabis kinbergii [Hemiptera: Nabidae] (1987)
    Springer
    BioControl 32 (1987), S. 303-309 
    Details
    ISSN: 1573-8248
    Keywords: Pacific damsel bug ; nabid ; functional response ; Punaise du Pacifique ; nabide ; réponse fonctionnelle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Description / Table of Contents: Résumé La punaise,Nabis kinbergii Reuter est rencontrée communément dans les champs de luzerne à la fin de l'été et durant l'automne en Nouvelle Zélande. Son potentiel en tant que prédateur des espèces communes d'insectes ravageurs n'a pas encore été étudié. Ce travail rend compte de la roponse fonctionnelle des femelles adultes et des 5e stades larvaires de cette punaise vis-à-vis de deux espèces proies, le miride:Sidnia kinbergi (Stal) et le puceron du pois:Acyrtosiphon pisum (Harris). Une équation deHolling (1959) de type II définit bien la réponse fonctionnelle de ce prédateur sauf lorsque les 5e stades n'ont que des nymphes du Miride pour proie. Cette punaise,Nabis kinbergii manifeste des réponses identiques à celles d'un autreNabidae: Reduviolus americoferus (L.).
    Notes: Abstract The functional responses of adult and 5th instar Pacific damsel bug,Nabis kinbergii Reuter were determined under laboratory conditions using Australian crop mirid,Sidnia kinbergi (Stal), and pea aphid,Acyrthosiphon pisum (Harris) as prey.Holling's (1959) type II equation was found to adequately define the functional response of this predator except when 5th instar nymphs were provided with Australian crop mirid as prey. In this instance, a type III response was found.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02373255
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...