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  • 1990-1994  (3)
  • 1990  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 81 (1990), S. 155-161 
    ISSN: 1432-0533
    Keywords: Pick's disease ; Substantia nigra ; Pigmented neurons ; Morphometry ; Parkinsonism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Loss of neurons from the substantia nigra (SN), which is often encountered in Pick's disease, was quantitatively analyzed in 13 cases of Pick's disease and 19 age-matched controls. On sections from the upper and lower portions of the SN, the pigmeted zone (zona compacta) and the non-pigmented zone (zona reticulata) were delineated, and these zones were partitioned into quarters: medial, mid-medial, mid-lateral and lateral. Neuronal loss was fairly severe and more evident in the upper section of the SN (−40%), especially in the midmedial and lateral quarters. In the lower section (neuronal loss:−28%), the medial quarter was most severely affected. Non-pigmented neurons were preserved. Fibrillary gliosis was denser in the zona reticulata, where neuronal loss was minimal. These findings revealed a selective vulnerability of nigral neurons according to their topography and pigmentation and suggests the primary involvement of some neuronal groups (especially the pigmented neurons) of the SN in Pick's disease.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 46 (1990), S. 514-517 
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The absolute values of the structure factors of diamond are determined for nine low-order reflections by measuring the X-ray Pendellösung beats on the wavelength scale. Parallel-sided wafers of synthetic diamond single crystals are used for specimens. The deformation charge density and the Debye-Waller B factor are evaluated from the structure factors. The charge density of pile-up electrons is estimated to be 0.44(17) eÅ-3 at the midpoint between the nearest-neighbour atoms. The density is slightly smaller than that determined by the powder diffraction method. The obtained B factor, 0.142 (9) Å2, is in good agreement with that evaluated to date from neutron diffraction measurements.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 237 (1990), S. 103-106 
    ISSN: 1432-1459
    Keywords: Vitamin E deficiency ; Fat malabsorption ; Diabetes mellitus ; Chronic pancreatitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Thirteen patients with adult-onset vitamin E deficiency due to fat malabsorption were investigated clinically and electrophysiologically. These patients had slightly or moderately decreased serum vitamin E (1.7–4.8 μg/ml, normal 〈6.0) or vitamin E/cholesterol ratio (0.21–0.31 mg/g, normal 〈0.35). Only one patient had typical neurological manifestations of vitamin E deficiency, which improved with supplementary vitamin E. The pathological findings in this patient were also compatible with vitamin E deficiency. This patient had poorly controlled diabetes mellitus due to advanced chronic pancreatitis. Reviewing previously reported cases of vitamin E deficiency with diabetes mellitus in chronic pancreatitis, the duration of deficiency until the onset of symptoms was shorter than in those cases without complications. Although adult patients with early, slight deficiency of vitamin E are generally asymptomatic, patients with diabetes mellitus tend to have early neurological symptoms. The vitamin E tolerance test should be used, because even in some patients with vitamin E deficiency due to malabsorption, the deficiency can be overcome by large oral doses of vitamin E.
    Type of Medium: Electronic Resource
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