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  • 1990-1994  (8)
  • 1992  (1)
  • 1991  (7)
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  • 1990-1994  (8)
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  • 1
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Two-dimensional gel electrophoresis was used to follow low changes in gene expression associated with antibiotic (bialaphos) biosynthesis in Streptomyces hygroscopicus. Cultures were pulse-labelled with [35S]-methionine before, during, and after the switch from primary to secondary metabolism in order to compare kinetic profiles of bialaphos (antibiotic) production (bap) genes during this metabolic transition. Separation of gene products on two-dimensional gels revealed that 27 were dependent on brpA for optimal expression and were activated as the culture approached stationary phase. Genes which encoded 10 brp4-dependent proteins were mapped to a 10 kb Sstl fragment of the 35 kb bap gene cluster by expressing them in Streptomyces lividans using the thiostrepton-inducible tipA promoter. N-terminal amino acid sequences of two brpA-dependent proteins, obtained by direct microsequencing of protein spots excised from two-dimensional gels, identified them as gene products mapping to the same region and involved in secondary metabolic conversions of the bap pathway. The kinetics of synthesis of 16 brpA-dependent gene products were characterized using QUEST computer software. Cluster analysis performed on the kinetics of synthesis of 346 of the most highly expressed gene products of HP5-29, including 16 brpA-dependent ones, identified 75 families having distinct patterns of expression. Many brpA-dependent proteins were clustered together; 10 were found in one kinetic family. These kinetic families also included brpA-independent gene products perhaps subject to similar regulatory mechanisms and thus possibly involved in bialaphos biosynthesis. The activation/derepression of bap expression took place as cultures approached stationary phase and was temporally related to synthesis of ppGpp.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 18 (1991), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Under acute conditions, maxillofacial injuries may be treated without the opportunity for an assessment of occlusal irregularities, even when there are mandibular fractures, because life-threatening injuries have priority over occlusion. Consequently, mandibular fractures may result in post-trauma malocclusion and facial deformity.The case history reported is of amale patient who had been involved in a traffic accident in childhood and suffered mandibular fractures. The initial incomplete man- agement resulted in persistent deformation of the mandible, disturbance of dental occlusion and difficulty in mastication. These irregularities were corrected during childhood by non-operative orthodontic treatment.When the patient reached adulthood, some permanent teeth were malformed because the fractures had damaged some tooth germs. However, the permanent dentition in general was almost normal as a result of the corrected primary dentition. Although the alveolar deformity due to the injury remained, the mandibular base was satisfactorily remodelled.The case reported supports the view that early restoration of normal dental occlusion before the eruption of permanent teeth contributes to the establishment of good functional dental occlusion of the permanent teeth.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report an 11-year-old boy with diffuse pulmonary arteriovenous fistula (multiple telangiectasia type). Contrast echocardiography proved R to L shunting at the peripheral levels of the lungs. A definitive diagnosis was obtained by pulmonary arteriography.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 350 (1991), S. 592-594 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The first y-ray burst observed in the X-ray photon energy band was GB720427, which was detected in the 2-8 keV range4. X-ray data from GB720514 provided some evidence5 that an accompanying X-ray signal might have lasted longer than the y-ray event. Detailed X-ray observations of four catalogued ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 26 (1991), S. 1749-1754 
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Corrosion behaviour of Si3N4 ceramics containing Y2O3, Al2O3 and AIN as sintering aids was investigated under hydrothermal conditions at 200–300
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1572-9540
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We report muon spin relaxation/rotation measurements on sintered powder samples of Nd2−x Ce x CuO4−y and a large single crystal of Nd2CuO4−y . We find an electronic phase diagram which is quite similar to that of hole-doped superconductors such as La2−x Sr x CuO4−y , although the doping of electrons into the system is less efficient in destroying the static moments on the copper spins. Static magnetic order in Nd2CuO4−y appears below about 250 K, and two spin reorientations are seen atT=75 K andT=35 K. Measurements of the magnetic field penetration depth have been unsuccessful due to the rare-earth paramagnetism of these materials.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1572-9540
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The negative muon spin rotation method (μ− SR) has been applied to studies of electronic states at oxygen sites of oxide superconductors YBa2Cu3O7, Nd2−x Ce x CuO4−δ (x=0.15, oxygen reduced), LiTi2O4 and related oxide-insulators La2CuO4−δ, CuO, Cu2O. The paramagnetic shifts of μ− trapped at oxygen nuclei in these polycrystalline powder samples have been measured at 300 K. All the measured shifts are positive. In copper-oxides the paramagnetic shifts are of the order 10−3, while in LiTi2O4 is very small (8.4±3.34×10−5). In YBa2Cu3O7, a fast μ− spin relaxation timeT 2 * (∼ 200 ns) has been observed; the reason for this is unknown and further studies are now in progress.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1573-093X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The Hard X-ray Telescope (HXT) is a Fourier-synthesis imager; a set of spatially-modulated photon count data are taken from 64 independent subcollimators and are Fourier-transformed into an image by using procedures such as the maximum entropy method (MEM) or CLEAN. The HXT takes images of solar flares simultaneously in four energy bands, nominally 15 (or 19)–24, 24–35, 35–57, and 57–100 keV, with an ultimate angular resolution as fine as ∼ 5 arc sec and a time resolution 0.5 s. Each subcollimator has a field of view wider than the solar disk. The total effective area of the collimator/detector system reaches ∼ 70 cm2, about one order of magnitude larger than that of the HINOTORI hard X-ray imager. Thanks to these improvements, HXT will for the first time enable us to take images of flares at photon energies above ∼ 30 keV. These higher-energy images will be compared with lower-energy ones, giving clues to the understanding of nonthermal processes in solar flares, i.e., the acceleration and confinement of energetic electrons. It is of particular importance to specify the acceleration site with regard to the magnetic field figuration in a flaring region, which will be achieved by collaborative observations between HXT and the Soft X-ray Telescope on board the same mission.
    Type of Medium: Electronic Resource
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