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  • 1990-1994  (2)
  • 1985-1989
  • 1991  (2)
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  • 1990-1994  (2)
  • 1985-1989
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  • 1
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Aufgrund epidemiologischer Überlegungen wird geschlossen, daß Voll-AIDS möglicherweise nur dann auftritt, wenn der entsprechende Patient mit dem humanen Immundefizienzvirus (HIV) und außerdem mit einem weiteren infektiösen Koagens infiziert ist. Da sich die Ausbreitungsdynamik der AIDS-Fälle mit Manifestation von Kaposi-Sarkom wesentlich von der der Fälle ohne Kaposi-Sarkom unterscheidet, wird vermutet, daß für die Ausprägung von AIDS mit bzw. ohne Beteiligung von Kaposi-Sarkom jeweils eigenständige Koagenzien verantwortlich sind. Unsere formalen epidemiologischen Argumente scheinen durch neuere mikrobiologische Ergebnisse gestützt zu werden.
    Notes: Summary Through epidemiological considerations we conclude that full-blown AIDS may occur only if the index patient is infected by the human immunodeficiency virus (HIV) and, in addition, by some other infectious coagent. Since the dynamical behaviour of the spread of AIDS cases with manifestation of Kaposi's sarcoma differs fundamentally from that of the non-Kaposi cases, we conjecture that two independent coagents (together with HIV) are responsible for the outbreak of full-blown AIDS with or without manifestation of Kaposi's sarcoma, respectively. Our formal epidemiological considerations appear to be supported by recent microbiological findings.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2014-03-06
    Description: The rapidly increasing number of AIDS cases requires a realistic estimation of the future development of the HIV/AIDS disease. For that purpose we develop a large system of coupled nonlinear differential equations describing simultaneously the dynamics of the development of the disease, the population size, the gender and age structure. A set of 1650 coupled equations are linked by balanced parameters. The balancing procedure is described by a set of (formally) 2,178,000 additional algebraic conditions. As the considered system is stiff, it requires new special extrapolation methods combined with techniquees of dynamical sparsing for the solution of sparsely filled systems. According to our simulations we expect 19,0,000 deaths caused by AIDS in the Federal Republic of Germany (former territories) in the year 2000. Such an epidemical spread would tie up about 4-7 percent of the actual health care workers.
    Keywords: ddc:000
    Language: German
    Type: reportzib , doc-type:preprint
    Format: application/pdf
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