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  • 1
    Electronic Resource
    Electronic Resource
    WILLIAM EDWARD SCHEVILL 1906-1994 (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Marine mammal science 11 (1995), S. 0 
    Details
    ISSN: 1748-7692
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1748-7692.1995.tb00300.x
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  • 2
    Electronic Resource
    Electronic Resource
    The nature of ophthalmic services, and the education and qualifications of nurses: a national survey (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of advanced nursing 22 (1995), S. 0 
    Details
    ISSN: 1365-2648
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This paper reports on a national survey undertaken by the Royal College of Nursing (RCN) Ophthalmic Nursing Forum to assess, first, the nature of ophthalmic services and, second, skill-mix and educational opportunities of nurses working with ophthalmic patients A questionnaire was formulated and tested by members of the committee, with research and statistical support from the School of Nursing Studies, University of Manchester The questionnaire was sent to the total population of ophthalmic units/hospitals in the UK (n= 168) Following descriptive statistical data analysis it was concluded that in smaller
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2648.1995.tb02643.x
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  • 3
    Electronic Resource
    Electronic Resource
    Effect of hydralazine on myocardial plasma membrane fatty acid binding protein (PM-FABP) during diabetes mellitus (1995)
    Springer
    Molecular and cellular biochemistry 148 (1995), S. 39-44 
    Details
    ISSN: 1573-4919
    Keywords: diabetes mellitus ; cardiomyopathy ; hydralazine ; cardiomyocytes ; fatty acids ; fluorescence ; trans-parinaric acid ; cis-parinaric acid ; plasma membrane fatty acid binding protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Chronic treatment with the antihypertensive drug hydralazine did not affect the hyperglycemic state of streptozotocin (STZ)-diabetic rats but did prevent the serum hyperlipidemia that is synonymous with these diabetic animals. After 6 weeks, untreated STZ-diabetic rats exhibited a 659% increase in serum triglycerides and 292% increase in serum cholesterol versus age-matched non-diabetic rats. Hydralazine-treated STZ-diabetic rats had serum triglyceride and cholesterol levels that did not differ from controls. Myocytes from control rats showed a preference for binding of the unsaturated fatty acid analog cis-parinaric acid vs the saturated fatty acid analog trans-parinaric acid. This preference was not altered in STZ-diabetic rat myocytes; hydralazine-treatment of STZ-diabetic rats also showed no change in fatty acid preference. STZ-diabetes caused a decrease in the affinity (Kd) for the trans, but not the cis-parinaric acid. However, total binding of both analogs was increased in STZ-diabetes. Hydralazine treatment of STZ-diabetic rats resulted in even greater total binding of both analogs. Affinity for the trans analog was further decreased in these hydralazine-treated rats, but the affinity for the cis analog was increased beyond control animals. These results suggest that the diabetic state influences the binding characteristics of the myocardial PM-FABP and that hydralazine, while reducing serum lipids in diabetes, has complex effects on the fatty acid binding by this protein.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00929501
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  • 4
    Electronic Resource
    Electronic Resource
    A combined magnetic sector-time-of-flight mass spectrometer for structural determination studies by tandem mass spectrometry (1995)
    New York, NY : Wiley-Blackwell
    Rapid Communications in Mass Spectrometry 9 (1995), S. 1227-1233 
    Details
    ISSN: 0951-4198
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: A combined magnetic sector-time-of-flight instrument has been constructed and used with both continuous (liquid secondary ion mass spectrometry and electrospray ionization) and pulsed (matrix-assisted laser desorption/ionization) ion sources. The design includes provision for both low- and high-energy gas collision induced decompositions and orthogonal acceleration of the product ions into the time-of-flight mass analyser. Tandem mass spectra may be acquired for singly and multiply charged precursor ions and reliable mass measurements are easily obtained. Product-ion mass spectra are quite reproducible regardless of any instability in the precursor ion beam intensity.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/rcm.1290091302
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    Paper (German National Licenses)
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