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  • 1
    ISSN: 1573-773X
    Keywords: classification of seismic events ; fuzzy logic ; half-distributed coding ; incomplete data ; learning ; multi-layer perceptron
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract This letter presents a method for modelling and processing incomplete data in connectionist systems. The approach consists in applying a neuro-fuzzy coding to the input data of a neural network. After an introduction to the different kinds of imperfections, we propose a neuro-fuzzy coding in order to take incomplete data into account. We show the efficiency of this coding on the problem of the classification of seismic events. The results show that a neuro-fuzzy coding of the inputs of a neural network increases the performance and classifies incomplete data with little affect on the results.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Cambridge, MA, USA : Blackwell Publishing Inc
    Restoration ecology 6 (1998), S. 0 
    ISSN: 1526-100X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: In France the alteration of species-rich grasslands is due mainly to agriculture and civil engineering projects (roadways, dams, ski resorts, etc.). The restoration of such ecosystems has been tested in many regions and after many sorts of degradation. According to the level of initial degradation, different responses can be envisioned. Some variations are presented of a general model of restoration and rehabilitation: (1) rejuvenation of fallow land by grazing with rustic animal breeds in wetlands or chalk grasslands in south and northwestern France, (2) restoration by recovery of extensive agricultural management in intensive agricultural areas such as the Rhône or Meuse Valleys, and (3) rehabilitation by appropriate ecological engineering carried out in grasslands degraded by intensification, ski-track, or civil engineering installations. Despite some positive results, these undertakings have not always had the expected effects and therefore should not provide alibis for the destruction of natural grasslands. In general, the success of such undertakings depends on the maintenance in the surrounding areas of protected seed source reservoirs and on the persistence of a diversified landscape pattern permitting connectivity between these seed sources and the restoration or rehabilitation sites.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Continuous exposure of cells to agonists develops a process that determines the extent to which the cells eventually respond to further stimuli. Here we used CATH.a cells (a catecholaminergic neuron-like cell line), which express pituitary adenylate cyclase-activating polypeptide (PACAP) receptors linked to both adenylyl cyclase and phospholipase C-β pathways, to investigate the influence of prolonged hormonal treatment on dual signaling and gene transcription. Prolonged incubation of cells with PACAP failed to down-regulate the density and affinity of membrane binding sites and caused opposite changes in messenger systems: PACAP-stimulated cyclic AMP accumulation was attenuated in a time- and dose-dependent fashion (t1/2 = 6.7 h and IC50 = 0.1 nM), whereas phosphoinositide turnover was overstimulated. Both effects were insensitive to pertussis toxin, whereas the drop in cyclic AMP concentration was also unchanged in the presence of 3-isobutyl-1-methylxanthine, indicating that neither Gi-like proteins nor cyclic nucleotide phosphodiesterases play a critical role in these processes. Blockade of protein synthesis with cycloheximide, as well as inhibition by H89 of cyclic AMP-dependent protein kinase (but not by bisindolylmaleimide of protein kinase C) antagonized the influences exerted by PACAP on adenylyl cyclase activity and inositol phosphate formation. Transcription of the chimeric GAL4-CREB construct, transiently transfected into CATH.a cells, was stimulated by PACAP, and this effect was potentiated as a result of chronic PACAP treatment. The results of the present investigation provide new insight into the possible differential regulation and cross-talks of transduction signals of receptors linked to multiplex signaling. They demonstrate that prolonged exposure of CATH.a cells to PACAP results in the desensitization of the cyclic AMP pathway and superinduction of the inositol phosphate signal, through protein neosynthesis and cyclic AMP-dependent protein kinase activation. At the same time, they show that desensitization of cyclic AMP signaling not only fails to hamper, but actually amplifies PACAP-stimulated CREB-regulated transcription.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 84 (1998), S. 6659-6666 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The presence of a parasitic surface film of 80 nm thickness has been observed by x-ray reflectivity on the top of some p+ type porous silicon layers, related to a contamination of the substrate. After testing several methods to clean the substrate and to avoid this film, it was found that a 300 °C thermal annealing of the substrate is sufficient to obtain a homogeneous porous layer. The thickness of the perturbed surface layer is determined by anodic oxidation experiments and the effect of the parasitic surface film on the porous silicon formation is studied by comparing porous layers formed on untreated and on annealed substrates. The hypothesis of a passivation of the boron doping atoms by hydrogen is discussed and we review the observations of nonhomogeneous porous layers which could be related to such a contamination problem. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 83 (1998), S. 2888-2893 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have developed an experimental setup for the measurement of the polarizability anisotropy of push–pull molecules in solution. We have used this technique to investigate prototype push–pull molecules that have been incorporated as doping chromophores in low glass transition temperature photorefractive polymers. Results obtained evidence for these compounds that the refractive index modulation is dominated by the orientational birefringence contribution while the electro-optic contribution remains small. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 72 (1998), S. 2583-2585 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Rapid thermal processing for junction formation is emerging as a low cost technique for solar cell as well as for other semiconductor device production. Compared to conventional furnace processing, process differences are not only in very high heating and cooling rates, but also in the incoherent emitted radiation spectrum, which can act on dopant diffusion. The photons emitted from tungsten halogen lamps go from far ultraviolet, over visible to infrared light. In this work additional mercury ultraviolet lamps are used during rapid thermal annealing to analyze the influence of high energetic photons on diffusion mechanisms. The diffusion results are discussed in terms of radiation spectrum, involving analysis of diffusion profiles and sheet resistances. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 25 (1998), S. 0 
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract. Bleeding on probing and the presence of deep periodontal pockets are considered to be the best site-specific indicators for periodontal disease progression during the maintenance phase of periodontal therapy. A major emphasis of supportive periodontal care (SPC) programs, therefore, has been the control of bleeding pockets. This investigation retrospectively evaluated the changes in the prevalence of bleeding on probing, periodontal pockets, bleeding periodontal pockets and the prevalence of tooth loss in a random sample of 273 periodontal patients participating in a supportive maintenance care program at a University Clinic. During an observation period of 67±46 months (range 5 months to 23 years), the overall incidence of all causes of tooth mortality was 0.23 ±0.49 teeth per patient per year of observation. 56% of subjects, however, did not experience any tooth loss, while less than 10% of patients lost more than 3 teeth. Thus, participation m the SPC program was effective in preventing tooth loss in the majority of patients. During the SPC period, however, a significant increase in the prevalence of periodontal pockets, and of bleeding on probing positive periodontal pockets, in particular, was observed. At completion of active periodontal therapy. 56.4% of patients were free from bleeding pockets. This decreased to a mere 13.6% at the latest SPC evaluation. The observed increases in the number of bleeding pockets was significantly associated with: longer times since completion of active periodontal therapy, more advanced periodontal diagnosis, higher %s of bleeding sites in the dentition, cigarette smoking, lack of inclusion of periodontal surgery in the active treatment phase, tooth loss, and the response to the active phase of periodontal treatment. The data presented in the paper indicate that the observed increase in the prevalence of bleeding pockets and tooth loss was not homogeneously distributed in the studied SPC population. better knowledge of risk indicators may lead to improved and more efficient risk management efforts during periodontal maintenance care.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Kyklos 51 (1998), S. 0 
    ISSN: 1467-6435
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Sociology , Economics
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Plant, cell & environment 21 (1998), S. 0 
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: We have investigated the way in which the radiation absorbed by leaves affects the rate of elongation of maize (Zea mays L.) roots. In five repeated growth chamber experiments, plants previously grown at a photon irradiance of 23 mol m–2 d–1 received either 7 or 34 mol m–2 d–1 from day 10 to day 20 after germination. The elongation rate of primary roots steadily decreased for 4 d after reduction in irradiance and then stabilized at 60% of that in plants at high irradiance. The elongating zone was slightly shorter after 2 d at low irradiance, and was further reduced after 8 d. The concentrations of sucrose and glucose in the elongating zone were greatly decreased after 2 d at low irradiance and the gradient of both sugars was suppressed. The longer period at low irradiance affected neither sugar content nor gradient. In the same way, cell production rate was reduced after 2 d at low irradiance and was not appreciably decreased afterwards. The root zone with cell division was shorter in plants at low irradiance, but cell division rate remained nearly constant temporally and spatially, and was unaffected by the irradiance treatment. Our results suggest that primary events after a reduction in irradiance were a change in cell flux and sugar content in the elongating zone. Change in elongation rate was slower and probably the result of a time-related developmental effect, which may be related to the change in cell production.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The locus cœruleus is innervated by proopiomelanocortin (POMC)-derived peptide immunoreactive fibres. The biological effects of α melanocyte-stimulating hormone (αMSH) and β-endorphin on second messengers (cAMP, inositol phosphates) and gene transcription were studied in the locus cœruleus-derived cell line CATH.a. RT-PCR analysis revealed the presence of four MSH receptor subtypes (1, 3, 4 and 5). Activation of these receptors by diacetyl αMSH stimulated cAMP accumulation in a dose-dependent manner (EC50: 4 × 10–9m). Diacetyl αMSH stimulated transcription from reporter genes driven by the c-fos or tyrosine hydroxylase promoter. This effect was abolished when protein kinase A was inactivated with a dominant inhibitory mutant. RT-PCR analyses revealed the presence of δ-, but not μ-and κ-opioid receptor. Pharmacological analysis showed that β-endorphin (EC50: 2.5 × 10–8m), but not N-acetyl β-endorphin, antagonized the biological effect of diacetyl αMSH on cAMP production and gene transcription. Since N-acetylation regulates the biological activity of αMSH and β-endorphin in an opposite manner, we propose a model where the rate of secretion dictated by the bioelectric activity of the presynaptic neuron modulates POMC-derived peptide maturation and the resulting biological signal sensed by the postsynaptic plate.
    Type of Medium: Electronic Resource
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