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  • 1
    Electronic Resource
    Electronic Resource
    Hugoniot data for iron (2000)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 88 (2000), S. 5496-5498 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A definitive set of the Los Alamos Hugoniot data for iron in a pressure regime extending to 442 GPa is given. Earlier standards data, obtained using conventional explosive systems, were thoroughly reprocessed. All original film records were reread. On the basis of more recent experiment and theory, some data were culled because the experimental designs were found to be insufficiently conservative. The analysis was also modified to take into account preheating of the explosively driven flyer plates. Minor clerical errors in transcription of measurements were corrected. An improved algorithm for the flash-gap time correction was incorporated. Higher-pressure data were obtained using a conventional 13-pin target assembly on a two-stage light gas gun. Several polynomial representations of the data are given. A linear fit to the data (Us=3.935+1.578 Up, where the shock velocity Us and the particle velocity Up are in km/s) has a root-mean-square misfit of 62 m/s. The quadratic fit (Us=3.691+1.788 Up−0.038 Up2) has a root-mean-square misfit of 39 m/s. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1319320
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  • 2
    Electronic Resource
    Electronic Resource
    The ECG pad lottery – it could be you! (2000)
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 55 (2000), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2044.2000.01425-36.x
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  • 3
    Electronic Resource
    Electronic Resource
    The accuracy of the pseudopotential approximation. III. A comparison between pseudopotential and all-electron methods for Au and AuH (2000)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 113 (2000), S. 7110-7118 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The quality of the pseudopotential approximation has been tested thoroughly by calculating spectroscopic properties of the gold atom and ground state AuH for eight different effective core potentials using Hartree–Fock, second-order Møller–Plesset and coupled cluster methods. The pseudopotential valence basis set {cursive-phi}v for Au was chosen to be identical for all pseudopotentials, a subset of the all-electron basis set {cursive-phi}v⊂{cursive-phi}AE, and the condition was applied that all sets are of near basis set limit quality. The pseudopotential results are compared with data obtained from nonrelativistic, scalar relativistic Douglas–Kroll and fully relativistic four-component all-electron calculations. The variation between the results obtained for all valence electron small-core pseudopotentials and all electron Douglas–Kroll calculations is found to be small (for the Stuttgart pseudopotential Δre=0.001 Å, ΔDe=0.03 eV, Δωe=9 cm−1, Δμe=0.04 D). Sizable differences to all electron results are only found for the 11 valence electron large-core pseudopotentials. The effects of the basis set superposition error on spectroscopic constants were investigated. Calculated coupled cluster electron affinities and ionization potentials for gold and spectroscopic properties for AuH were found to be in excellent agreement with available experimental data. The variation between the different small-core pseudopotentials for one particular spectroscopic property is shown to be less than the error due to the incompleteness of electron correlation procedure or the basis set and approximately of the same size as the basis set superposition error. The results show that scalar relativistic effects for valence properties are perfectly described by the pseudopotential approximation. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1313556
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  • 4
    Electronic Resource
    Electronic Resource
    Growth and survival of juvenile yellowtail flounder Pleuronectes ferrugineus (Storer) under different photoperiods (2000)
    Oxford, UK : Blackwell Science Ltd
    Aquaculture research 31 (2000), S. 0 
    Details
    ISSN: 1365-2109
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Yellowtail flounder Pleuronectes ferrugineus (Storer) have been identified as a potential species for coldwater aquaculture along the north-east coast of Canada. It has been shown that increased photoperiods improve growth and survival during the larval stage of this species. We conducted two experiments to determine the effect of photoperiod on the growth and survival of juveniles. The first experiment compared growth and survival under 24-, 18- and 12-h lighting per day with a restricted food ration. The second experiment compared growth and survival rates under the above photoperiods and ambient lighting with fish being fed to satiation. No significant differences in growth or survival were found in juveniles under the different photoperiods in either experiment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2109.2000.00480.x
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  • 5
    Electronic Resource
    Electronic Resource
    Substance P induction of murine keratinocyte PAM 212 interleukin 1 production is mediated by the neurokinin 2 receptor (NK-2R) (2000)
    Copenhagen : Munksgaard International Publishers
    Experimental dermatology 9 (2000), S. 0 
    Details
    ISSN: 1600-0625
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: The neurological system plays an important role in modulating some inflammatory skin diseases. Neuro-cutaneous interactions may be mediated by the release of neuropeptides such as substance P (SP) which activate immunocompetent cells in the skin by binding to high affinity neurokinin receptors (NKR). Since epidermal keratinocytes produce a variety of cytokines and are intimately associated with cutaneous sensory fibers, we tested the ability of these cells to participate in the cutaneous neuroimmune system by the secretion of potent cytokines such as interleukin 1 (IL-1) in response to released SP. RT-PCR studies demonstrated that cultured PAM 212 murine keratinocytes expressed mRNA for NK-2R but not NK-1R. Correspondingly, the addition of SP to these cells resulted in a rapid increase in intracellular Ca2+ levels that could be specifically blocked by an NK-2R antagonist. NK-2R was also shown in normal mouse epidermis by immunohistochemistry. SP augmented the expression of PAM 212 keratinocyte IL-1α mRNA in a dose and time dependent manner and this induction was inhibited by an NK-2R antagonist. Secretion of bioactive IL-1α by the PAM 212 keratinocytes was likewise stimulated by SP in a dose dependent manner. These data support the hypothesis that SP released from cutaneous sensory nerves contributes to neuroimmune inflammatory responses in the skin by modulating the expression and release of cytokines from epidermal keratinocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0625.2000.009001042.x
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  • 6
    Electronic Resource
    Electronic Resource
    The role of MRI in screening for neurogenic hypertension (2000)
    Springer
    Neuroradiology 42 (2000), S. 99-103 
    Details
    ISSN: 1432-1920
    Keywords: Key words Hypertension arterial ; Medulla oblongata ; Compression ; Neurovascular ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Neurovascular compression (NVC) of the left ventrolateral medulla (VLM) has been implicated as a cause of essential hypertension. We investigated whether high-resolution MRI of the posterior cranial fossa could identify patients with essential hypertension who may benefit from surgery. A retrospective analysis of imaging and clinical records from 162 patients was performed. There were 38 patients with essential hypertension and 124 who were normotensive. Contact or compression of the VLM was present in 42.1 % (16/38) of the hypertensive group on the left and 47.3 % (18/38) on the right. In the normotensive group it was seen in 32.2 % (40/124) on the left and 26.6 % (33/124) on the right. There was no significant difference between the hypertensive and control groups with regard to contact or compression of the left VLM. The results support the contention that neurovascular compression (NVC) of the left or right VLM is a common finding on MRI in normotensive individuals. We therefore believe that high-resolution MRI cannot be used as a screening tool to identify patients who may benefit from surgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002340050023
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  • 7
    Electronic Resource
    Electronic Resource
    Effects of Risedronate Treatment on Bone Density and Vertebral Fracture in Patients on Corticosteroid Therapy (2000)
    Springer
    Calcified tissue international 67 (2000), S. 277-285 
    Details
    ISSN: 1432-0827
    Keywords: Key words: Corticosteroid — Risedronate — Calcium — Vitamin D — BMD
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. Men and women (n = 518) receiving moderate-to-high doses of corticosteroids were enrolled in two studies with similar protocols and randomly assigned to receive either placebo or risedronate (2.5 or 5 mg) for 1 year. All patients received daily calcium supplementation (500–1000 mg), and most also received supplemental vitamin D (400 IU). The primary endpoint was the difference between the placebo and active groups in lumbar spine bone mineral density (BMD) at 1 year; changes in BMD at other sites, biochemical markers of bone turnover, and the incidence of vertebral fractures were also assessed. In the overall population, the mean (SE) lumbar spine BMD increased 1.9 ± 0.38% from baseline in the risedronate 5 mg group (P 〈 0.001) and decreased 1.0 ± 0.4% in the placebo group (P= 0.005). BMD at the femoral neck, trochanter, and distal radius increased or was maintained with risedronate 5 mg treatment, but decreased in the placebo group. Midshaft radius BMD did not change significantly in either treatment group. The difference in BMD between the risedronate 5 mg and placebo groups was significant at all skeletal sites (P 〈 0.05) except the midshaft radius at 1 year. The 2.5 mg dose also had a positive effect on BMD, although of a lesser magnitude than that seen with risedronate 5 mg. A significant reduction of 70% in vertebral fracture risk was observed in the risedronate 5 mg group compared with the placebo group (P= 0.01). Risedronate was efficacious in both men and women, irrespective of underlying disease and duration of corticosteroid therapy, and had a favorable safety profile, with a similar incidence of upper gastrointestinal adverse events in the placebo and active treatment groups. Daily treatment with risedronate 5 mg significantly increases BMD and decreases vertebral fracture risk in patients receiving moderate-to-high doses of corticosteroid therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002230001146
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  • 8
    Electronic Resource
    Electronic Resource
    Herbicide Spray Drift Odor: Measurement and Toxicological Significance (2000)
    Springer
    Archives of environmental contamination and toxicology 38 (2000), S. 390-397 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract. The toxicological significance of exposure of members of the public to spray drift odors of four herbicide formulations (three 2,4-dichlorophenoxyacetic [2,4-D] acid derivatives and one MCPA [4-methyl-2-chlorophenoxyacetic acid] derivative) has been studied using a combination of novel odor measurement and classic residue analysis techniques. The mean odor concentrations, generated during the spraying of the commercial herbicide formulations under simulated aerial application conditions, were about twofold higher for 2,4-D ethylhexyl ester (22,500 OUc/m3) and MCPA (30,100 OUc/m3) than for 2,4-D butyl ester (12,400 OUc/m3) and 2,4-D amine (11,800 OUc/m3). Detailed investigations determined that the odors are due to trace manufacturing impurities and additives in the commercial formulations, whereas the herbicide active ingredients are odorless. Measured airborne herbicide active ingredient concentrations under the simulated aerial application conditions were all below their respective occupational safety and health TLV-TWA values, indicating that exposures of toxicological significance as a result of spray drift are unlikely.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002449910052
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  • 9
    Electronic Resource
    Electronic Resource
    Reduced vas deferens contraction and male infertility in mice lacking P2X 1 receptors (2000)
    [s.l.] : Macmillian Magazines Ltd.
    Nature 403 (2000), S. 86-89 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] P2X1 receptors for ATP are ligand-gated cation channels, present on many excitable cells including vas deferens smooth muscle cells. A substantial component of the contractile response of the vas deferens to sympathetic nerve stimulation, which propels sperm into the ejaculate, is ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/47495
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  • 10
    Electronic Resource
    Electronic Resource
    Comparison of Mechanical and Chemomechanical Polished SiC Wafers Using Photon Backscattering (2000)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 338-342 (May 2000), p. 841-844 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/04/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.338-342.841.pdf
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