Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 2005-2009  (4)
  • 1
    Electronic Resource
    Electronic Resource
    Chemical biology A degrading solution to pollution (2007)
    [s.l.] : Nature Publishing Group
    Nature 446 (2007), S. 499-500 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Dioxins are some of the most prevalent and dangerous pollutants in the environment. They are generated as by-products of, among other things, rubbish incineration and industrial processes, and act by disrupting the endocrine system. Because dioxins are fat-soluble, they tend to accumulate in the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/446499a
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities (2007)
    [s.l.] : Nature Publishing Group
    Nature 446 (2007), S. 876-881 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The spindle checkpoint prevents chromosome mis-segregation by delaying sister chromatid separation until all chromosomes have achieved bipolar attachment to the mitotic spindle. Its operation is essential for accurate chromosome segregation, whereas its dysregulation can contribute to birth defects ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature05694
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging (2007)
    [s.l.] : Nature Publishing Group
    Nature 447 (2007), S. 1135-1138 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Modification of proteins with ubiquitin or ubiquitin-like proteins (UBLs) by means of an E1–E2–E3 cascade controls many signalling networks. Ubiquitin conjugation involves adenylation and thioesterification of the carboxy-terminal carboxylate of ubiquitin by the E1-activating ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature05902
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Patterns of food allergen-specific cytokine production by T lymphocytes of children with multiple allergies (2005)
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 35 (2005), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background The contribution of different T cell subsets to the overall measured cytokine response to food allergens is largely unexplored.Method The patterns of cytokine production of peripheral blood-derived T cells after allergen stimulation were studied in 22 children with multiple food allergies and in 20 non-allergic children as controls, using flow cytometry.Results Proportions of T cells of food-sensitized children spontaneously secreting IFN-γ and IL-10 (without antigen stimulation) were lower than non-atopic children and adult controls (P〈inlineGraphic alt="leqslant R: less-than-or-eq, slant" extraInfo="nonStandardEntity" href="urn:x-wiley:09547894:CEA2355:les" location="les.gif"/〉0.001). The proportions of IL-4-producing cells in vitro were significantly increased (P〈inlineGraphic alt="leqslant R: less-than-or-eq, slant" extraInfo="nonStandardEntity" href="urn:x-wiley:09547894:CEA2355:les" location="les.gif"/〉0.04) and IFN-γ-producing cells were significantly reduced (P〈inlineGraphic alt="leqslant R: less-than-or-eq, slant" extraInfo="nonStandardEntity" href="urn:x-wiley:09547894:CEA2355:les" location="les.gif"/〉0.05) in sensitized children after incubation with and without dendritic cell presentation of peanut extract, β-lactoglobulin and ovalbumin. The reverse pattern was found in non-sensitized children and adult controls. IL-4 secretion in allergic children to sensitizing allergens was mainly restricted to the CD4+ CD45 RO+ population while in non-atopic controls both CD4+ and CD8+ CD45 RO+ cells produced mostly IFN-γ. Food-specific IgE values did not correspond with cytokine responses but IL-4 production and IFN-γ reduction relative to normal children were closely associated with total IgE levels.Conclusion Food-allergic children's IL-4 cytokine response to their relevant allergens is predominantly from a memory population of CD4+ CD45 RO+ cells, whereas IL-4 and IFN-γ secretion of non-allergic controls was predominantly from mixed CD4+ and CD8+ CD45 RO+ populations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.2005.02355.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...