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  • 1
    Electronic Resource
    Electronic Resource
    The influence of a spring habit gene, Vrn-D1, on heading time in wheat (2001)
    Oxford, UK : Blackwell Publishing Ltd
    Plant breeding 120 (2001), S. 0 
    Details
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: The adaptability of wheat cultivars to environmental conditions is known to be associated with a vernalization requirement, that is, spring/winter habit. To clarify the genetic effect of the spring habit gene, Vrn-D1, on heading time in the field, recombinant inbred lines (RILs) with or without the Vrn-D1 gene were produced from F2 plants of the cross between ‘Nanbukomugi’ and ‘Nishikazekomugi’, non-carrier and carrier cultivars of this gene, respectively. Using growth chambers with a controlled temperature and photoperiod, three components of heading time, i.e. vernalization requirement, photoperiodic sensitivity and narrow-sense earliness (earliness per se), were evaluated in each RIL. RILs with the Vrn-D1 gene (E lines) showed greatly reduced vernalization requirements and slightly shorter narrow-sense earliness than RILs without Vrn-D1 (L lines), although no difference in photoperiodic sensitivity was observed between the two groups. RILs were planted at four different sites in Japan and examined for their heading time in the field. E lines headed significantly earlier than L lines at all locations, indicating that the earliness of E lines is stable in various environmental conditions. These results indicated that spring habit caused by Vrn-D1 gene, as well as narrow-sense earliness, was responsible for heading time in the field.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1439-0523.2001.00586.x
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  • 2
    Electronic Resource
    Electronic Resource
    Role of male-sterile cytoplasm in resistance to barley yellow mosaic virus and Fusarium head blight in barley (2002)
    Oxford, UK : Blackwell Publishing Ltd
    Plant breeding 121 (2002), S. 0 
    Details
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Two types of male-sterile cytoplasm, designated msm1 and msm2, in barley were investigated to determine whether these cytoplasms confer resistance to barley yellow mosaic virus (Ba YMV) and Fusarium head blight (FHB). Alloplasmic lines and isogenic lines of two cultivars showed the same reaction to each Ba YMV as that of their euplasmic lines. This demonstrates that the barley male-sterile cytoplasms msm1 and msm2 have no effect on resistance to BaYMV. No significant difference in reactions to FHB was recognized among fertile alloplasmic lines of ‘Adorra’, but the difference in reactions to FHB between fertile and sterile isogenic lines of ‘Adorra’ was significant. The damage caused by FHB in the male-sterile lines that produced sterile pollen was significantly greater than the damage in a sterile line that did not produce pollen. These results suggest that pollen or anthers are important factors in infection with or spread of FHB. For production of hybrid seeds, male-sterile lines with no pollen production, such as those with msm1 male-sterile cytoplasm, would reduce FHB infestation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1439-0523.2002.00683.x
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  • 3
    Electronic Resource
    Electronic Resource
    Immunohistochemical localization of atrial natriuretic polypeptide (ANP) in human atrial and ventricular myocardiocytes (1988)
    Springer
    Histochemistry and cell biology 89 (1988), S. 411-413 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary To date, there have been few immunohistochemical investigations of atrial natriuretic polypeptide (ANP) in human cardiac tissue, especially the ventricles. In this study, myocardial tissue was obtained from two sources: the bilateral atria and ventricles at autopsy; and biopsy tissues from the right auricle and left ventricle of a patient with myocardial infarction undergoing surgery. These tissues were examined by the avidin-biotin immunoperoxidase technique using three kinds of primary ANP-antibodies. ANP-immunoreactivity was observed in the perinuclear region of myocytes of all tissues examined. The intensity of the reaction was stronger in atrial tissue, weaker in ventricular tissue. In the later tissue, the positive-staining myocytes were not part of the pulse-conducting system. Although the tissues we studied were not obtained from normal hearts, our data demonstrates that ANP-reactivity can be detected in ventricular myocytes outside the pulse-conducting system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00492595
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  • 4
    Electronic Resource
    Electronic Resource
    The pharmacokinetics ofα-human atrial natriuretic polypeptide in healthy subjects (1986)
    Springer
    European journal of clinical pharmacology 31 (1986), S. 101-103 
    Details
    ISSN: 1432-1041
    Keywords: atrial natriuretic polypeptide ; α-hANP ; pharmacokinetics ; radioimmunassay
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary We have analysed the pharmacokinetics ofα-human atrial natriuretic polypeptide (α-hANP) in healthy subjects, using a two-compartment open model following bolus intravenous injection. The plasma half-times for the fast and slow components were 1.7±0.07 min and 13.3±1.69 min respectively. V1 (the volume of the central compartment), Vz (volume of distribution) and Vss (volume of distribution at steady-state) were 5370±855 ml (89.5±14.3 ml·kg−1), 32000±4620 ml (533±77.0 ml·kg−1), and 11900±1530 ml (198±25.5 ml·kg−1) respectively. The mean plasma clearance was 1520±121 ml·min−1 (25.4±2.0 ml·min−1·kg−1.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00870995
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  • 5
    Electronic Resource
    Electronic Resource
    Effects of para-substituted beta-adrenoceptor blocking agents and methyl-substituted phenoxypropanolamine derivatives on maximum upstroke velocity of action potential in guinea-pig papillary muscles (1985)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 329 (1985), S. 77-85 
    Details
    ISSN: 1432-1912
    Keywords: Cardiac action potential ; Fast Na+ system of the cardiac membrane ; β-Adrenoceptor blocking agents ; Structure-activity relation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effects of atenolol (2–5 mmol/l), sotalol (1–2 mmol/l) and pamatolol (0.1–1 mmol/l), together with N-tertiary butyl phenoxypropanolamines with o-methyl (D-2T: 50–100 μmol/l) m-methyl (D-3T: 50–100 μmol/l) and p-methyl (D-4T:100–200 μmol/l) group as well as with o,p-methyl groups (D-24T) (50–100 μmol/l) on action potentials (APs) were investigated in isolated guinea-pig papillary muscles. All the drugs in these concentrations produced a concentration-dependent reduction of the maximum upstroke velocity (V max). The reduction ofV max in premature APs induced by stimuli interpolated between the basic driving rate of 0.25, 0.1 or 0.027 Hz decayed exponentially during diastolic intervals. The time constants of these decay processes τ for atenolol, pamatolol and sotalol ranged between 260–541 ms, those for D-3T and D-4T between 655–1,166 ms, and D-2T and D-24T between 1,565–1,931 ms. A drug which provided larger τ values caused the reduction ofV max in a wider range of the frequency. With respect to the aryloxypropanolamine derivatives so far studied (Sada and Ban 1980, 1981 a, b; Sada et al. 1983) fairly good correlations were found as follows: between logn-octanol/water partition coefficient (logP) and ED20 at 0.25 Hz, ED30 at 1 and 4 Hz for 11–14 compounds; between logP and resting block, between molecular weight and A o c i.e. the value extrapolated to the time of APD90 of the conditioning response relative to the predrugV max value which may represent a fraction of channels blocked per AP for 100 μmol/l of 20–22 compounds. With respect to 8 compounds with methyl substituents in the benzene ring or amine part the ortho methyl group makes a major contribution to increase the resting block and to increase log τ values.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00695196
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  • 6
    Electronic Resource
    Electronic Resource
    Effects of bucumolol, nadolol and nifenalol on maximum upstroke velocity of action potential in guinea pig papillary muscles (1986)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 332 (1986), S. 297-304 
    Details
    ISSN: 1432-1912
    Keywords: Cardiac action potential ; Fast Na+ system of the cardiac membrane ; β-Adrenoceptor blocking agents ; Structure-activity relation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effects of bucumolol (BUC), nadolol (NAD) and nifenalol (NIF) on contractile forces and on action potentials (APs) were investigated in isolated guinea pig atrial and papillary muscles, respectively. Log 1/ED40 values for the negative inotropic effects of these drugs were 0.097,10 and 0.74 mmol/l in this order. BUC (50 μmol/l), NAD (0.5 mmol/l) and NIF (0.2 mmol/l) produced about 60,20 and 20% reduction of V max at 1 Hz. The frequency-dependent reductions at these and higher concentrations were greatest for BUC, intermediate for NAD and least for NIF. These potencies at certain frequencies were, as a whole, consistent with log P-potency relationship established in our previous papers (Harada et al. 1981; Ban et al. 1985). The reductions of V max in APs in response to premature stimuli during basic stimuli at the rate of 0.25 or 0.027 Hz decayed exponentially during diastolic intervals (DI). The time constants of these decay processes (τ) estimated by linear and nonlinear regression analyses and by eye were 12.2–9.6 s for BUC (50–100 μmol/l) and 2.9–4.8 s for NAD (1–2 mmol/l) and 57–87 ms for NIF (0.2–1 mmol/l). In terms of the molecular weight (MW)-log τ relationship (Ban et al. 1985), these τ values are within the 95% fiducial limit for BUC and NAD and deviated from the lower fiducial limit for NIF. The frequency-dependent reductions of V max by these drugs were explained in terms of a function of τ and the intercept Ao. Based on the study mady by Cohen et al. (1984) we estimated the distortion of the time course of recovery of V max from that of sodium channel availability in the presence of drugs. Our computation shows that the relative change of the τ estimated at the same level of the zero-intercept does, but that of the τ estimated at different levels does not, reflext exactly that of the time constants of the recovery of sodium channel availability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00504871
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  • 7
    Electronic Resource
    Electronic Resource
    Ultrastructural and immunocytochemical studies on the cytoskeleton in the anterior pituitary of rats, with special regard to the relationship between actin filaments and secretory granules (1989)
    Springer
    Cell & tissue research 258 (1989), S. 25-30 
    Details
    ISSN: 1432-0878
    Keywords: Anterior pituitary secretory cells ; Actin filaments ; Secretory granules ; Intracellular transport ; Heavy meromyosin ; Rat (Wistar)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary As previously reported, in anterior pituitary cells of the rat, secretory granules are linked with adjacent granules, cytoorganelles, microtubules, and plasma membrane by thin filaments, 4–10 nm in diameter. The quick-freeze, deep-etching method revealed that some of the filaments linking adjacent secretory granules show 5 nm-spaced striations on their surface which are known to be characteristic of actin. Immunocytochemistry showed that actin is localized in the cytoplasm beneath the plasma membrane, and around or between secretory granules. The heavy meromyosin decoration method demonstrated that actin filaments are mainly located in the cytoplasm beneath the plasma membrane, while some actin filaments are connected with the limiting membrane of the secretory granules. The actin filaments associated with the secretory granules are considered to be involved in the intracellular transport of the granules, while those localized in the peripheral cytoplasmic matrix might control the approach of the secretory granules to the plasma membrane and their release.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00223140
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  • 8
    Electronic Resource
    Electronic Resource
    Cesium satellite band at 875.2 nm stemming from the Cs 2 0 g + (6 p 2 P 1/2 +6 s 2 S 1/2 ) state (2001)
    Springer
    The European physical journal 15 (2001), S. 209-214 
    Details
    ISSN: 1434-6079
    Keywords: PACS. 33.70.Jg Line and band widths, shapes, and shifts – 34.20.Cf Interatomic potentials and forces
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: We measured a very distinct satellite band at 875.2 nm between two resonance lines of cesium. Spectral simulation using Spies and Meyer [#!ref1!#] ab initio potential curves and an appropriate transition dipole moment function was compared with experimental profile. Implications of the investigated satellite band at 875.2 nm in the field of ultracold cesium atom collisions are discussed with a special emphasize to new possibilities of the photoassociation of two ground state atoms leading to the formation of ultracold intermediate long-range molecules.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003400000488.
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  • 9
    Electronic Resource
    Electronic Resource
    Rb $\mathsf{_{2}}$ diffuse band emission excited by diode lasers (2004)
    Springer
    The European physical journal 30 (2004), S. 57-64 
    Details
    ISSN: 1434-6079
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. We investigated collisional processes involved in the population of the Rb2 diffuse band through resonant excitation of Rb atoms. Near-infrared (780 nm) and violet (420 nm) diode lasers were used for the Rb first ( $\rm 5 ^{2}S_{1/2}\to 5 ^{2}P_{3/2}$ ) and second ( $\rm 5 ^{2}S_{1/2}\to 6 ^{2}P_{3/2}$ ) resonant doublet excitations. Laser induced fluorescence spectra were detected and investigated at different rubidium densities, buffer gas pressures and excitation wavelengths.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1140/epjd/e2004-00063-9
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