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  • 2000-2004  (1)
  • 1980-1984  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Measurement of krypton-85 in the atmosphere with a portable apparatus (1984)
    Springer
    Journal of radioanalytical and nuclear chemistry 81 (1984), S. 161-165 
    Details
    ISSN: 1588-2780
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Energietechnik
    Notizen: Abstract A portable apparatus was developed for the rapid collection, separation and counting of krypton-85 in the environmental air samples. The apparatus consists of a molecular sieve trap for the elimination of H2O and CO2, a charcoal trap for the collection of krypton, a chromatographic column for the isolation of krypton in the air sample and a vial for the dissolution of krypton in the scintillation solution. With this apparatus, krypton can be collected from half a cubic meter of air with 94% recovery in about 3 hrs. The measurements of krypton-85 have been done several times in Fukuoka area between the periods Jan. 30, 1981 and Dec. 9, 1981. And then, the krypton-85 concentration was found to be approximately 21 pCi/m3 air. The results were compared with those obtained by foregin investigators.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02132931
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Induction of natural killer suppressive factor in murine peritoneal cavity by intraperitoneal bolus administration of high-dose cisplatin (2000)
    Springer
    International journal of clinical oncology 5 (2000), S. 48-53 
    Details
    ISSN: 1437-7772
    Schlagwort(e): Key words Cisplatin ; Natural killer cell activity ; Natural killer suppressive factor ; Peritoneal cavity ; Intraperitoneal chemotherapy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Background. Intraperitoneal (i.p.) chemotherapy is frequently utilized in patients with advanced gastric cancer or peritoneal dissemination. We investigated whether i.p. administration of cisplatin at high or low doses would impair host local immunity with respect to the induction of natural killer (NK) cell suppressive factor in the murine peritoneal cavity. Methods. Cisplatin was administered at a total dose of 10 mg/kg according to two schedules: high-dose bolus injection (HB; 10 mg/kg) and low-dose consecutive injections (LC; 2 mg/kg daily for 5 days). The supernatant obtained from the peritoneal lavage fluid was added during normal splenocyte-mediated NK cytotoxicity assay. The phenotypes of peritoneal exudate cells were analyzed using anti-F4/80 monoclonal antibody (MAb) and anti-I-A MAb. Results. NK cell activity was significantly inhibited by the supernatant obtained from the HB group 7 days after the administration of cisplatin (40.6% of NK cell activity in controls; P 〈 0.05). This inhibition was partly restored by prostaglandin E2 (PGE2) antiserum (69.5% of NK cell activity in controls). NK cell activity was not inhibited at any point by exposure to the supernatant of the LC group. I-A− peritoneal macrophages were more abundant in the HB group than in the LC group (2.9 × 106 vs 4.6 × 105 on day 3; P 〈 0.05). Conclusion. These results suggest that intraperitoneal bolus administration of high-dose cisplatin induces NK suppressive factors, including PGE2, in the peritoneal cavity, whereas low-dose consecutive administration does not.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s101470050009
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