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  • 1
    Digitale Medien
    Digitale Medien
    s.l. : American Chemical Society
    Journal of the American Chemical Society 56 (1934), S. 1314-1315 
    ISSN: 1520-5126
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    s.l. : American Chemical Society
    Journal of the American Chemical Society 56 (1934), S. 1393-1394 
    ISSN: 1520-5126
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Futura Publishing, Inc.
    Pacing and clinical electrophysiology 24 (2001), S. 0 
    ISSN: 1540-8159
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: ANFINSEN, O.-G., et al.: When Should Heparin Preferably be Administered During Radiofrequency Catheter Ablation? RF catheter ablation is complicated by thromboembolism in about 1% of patients. Limited knowledge exists concerning when and how to use anticoagulation or antithrombotic treatment. We studied the activation of coagulation (prothrombin fragment 1 + 2 [PF1 + 2] and D-dimer), platelets (β-thromboglobulin [β-TG]) and fibrinolysis (plasmin-antiplasmin complexes [PAP]) during RF ablation of accessory pathways in 30 patients. They were randomized to receive heparin (100 IU/kg, intravenously) (1) immediately after introduction of the femoral venous sheaths (group I) or (2) after the initial electrophysiological study, prior to the delivery of RF current (groups II and III). Group II additionally received saline irrigation of all femoral sheaths. After the initial bolus, 1,000 IU of heparin was supplied hourly in all groups. Within groups II and III, median plasma values of PF1 + 2 and β-TG more than tripled (P ≤ 0.007) during the diagnostic study and gradually declined during heparin administration despite RF current delivery. Median D-dimer tripled (P = 0.005) and PAP doubled (NS) before heparin administration; then both remained around the upper reference values. In the early heparin group, however, PF1 + 2, Ddimer, and PAP did not rise at all, and β-TG showed only a slight increase towards the end of the procedure. The differences between group I versus groups II and III were statistically significant prior to the first RF current delivery (PF1 + 2, D-dimer, and β-TG) and by the end of the procedure (PF1 + 2, D-dimer, and PAP). In conclusion, “late” heparin administration allows hemostatic activation during the initial catheterization and diagnostic study. By administering intravenous heparin immediately after introduction of the venous sheaths, hemostatic activation is significantly decreased. Saline irrigation of the venous sheaths added nothing to late heparin administration.
    Materialart: Digitale Medien
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  • 4
    ISSN: 1471-4159
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Human lumbar CSF patterns of Aβ peptides were analysed by urea-based β-amyloid sodium dodecyl sulphate polyacrylamide gel electrophoresis with western immunoblot (Aβ-SDS–PAGE/immunoblot). A highly conserved pattern of carboxyterminally truncated Aβ1–37/38/39 was found in addition to Aβ1–40 and Aβ1–42. Remarkably, Aβ1–38 was present at a higher concentration than Aβ1–42, being the second prominent Aβ peptide species in CSF. Patients with Alzheimer's disease (AD, n = 12) and patients with chronic inflammatory CNS disease (CID, n = 10) were differentiated by unique CSF Aβ peptide patterns from patients with other neuropsychiatric diseases (OND, n = 37). This became evident only when we investigated the amount of Aβ peptides relative to their total Aβ peptide concentration (Aβ1–x%, fractional Aβ peptide pattern), which may reflect disease-specific γ-secretase activities. Remarkably, patients with AD and CID shared elevated Aβ1–38% values, whereas otherwise the patterns were distinct, allowing separation of AD from CID or OND patients without overlap. The presence of one or two ApoE ε4 alleles resulted in an overall reduction of CSF Aβ peptides, which was pronounced for Aβ1–42. The severity of dementia was significantly correlated to the fractional Aβ peptide pattern but not to the absolute Aβ peptide concentrations.
    Materialart: Digitale Medien
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  • 5
    Digitale Medien
    Digitale Medien
    s.l. : American Chemical Society
    Industrial and engineering chemistry 6 (1934), S. 187-188 
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    s.l. : American Chemical Society
    Industrial & engineering chemistry 24 (1932), S. 547-548 
    ISSN: 1520-5045
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 7
    Digitale Medien
    Digitale Medien
    350 Main Street , Malden , MA 02148-5018 , USA , and 9600 Garsington Road , Oxford OX4 2DQ , UK . : Blackwell Science Inc
    Journal of cardiovascular electrophysiology 15 (2004), S. 0 
    ISSN: 1540-8167
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Introduction: Modification of AV nodal conduction by radiofrequency ablation (RFA) results in a variable reduction in heart rate during atrial fibrillation (AF). Using AF induced in patients with dual AV nodal pathways as a model, we tested the effect of additional treatment with digitalis (ouabain) and beta-blocker (esmolol). Methods and Results: Ten patients were randomized to control (group I) and studied only before ablation. AF was induced in 30 patients before and after slow pathway ablation (group II). Mean ventricular cycle lengths (AF CLmean) were recorded. Slow pathway conduction was eliminated after ablation in 10 patients (group IIA), whereas slow pathway conduction was still present in 20 patients (group IIB). Compared to pre-RFA there was a 10% increase in AF CLmean post-RFA (P 〈 0.01). During isoproterenol infusion the increase was 8% (P = NS). Adding digitalis and beta-blocker during isoproterenol infusion increased AF CLmean by 75% (95% in group IIA) compared to 36% in group I (P 〈 0.001 II vs I). Conclusion: Slow pathway ablation reduces ventricular rate during AF. Addition of digitalis and beta-blocker during isoproterenol infusion significantly decreases ventricular rate after ablation compared to the control group. The finding suggests that beta-blocker has significant effects on fast AV nodal pathway conduction during induced AF with isoproterenol infusion.
    Materialart: Digitale Medien
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  • 8
    Digitale Medien
    Digitale Medien
    Springer
    Mund-, Kiefer- und Gesichtschirurgie 4 (2000), S. 309-314 
    ISSN: 1434-3940
    Schlagwort(e): Schlüsselwörter Odontogene Zyste ; Laterale parodontale Zyste ; Botryoide odontogene Zyste ; Kieferzyste ; Zytokeratine ; Keywords Odontogenic cyst ; Lateral periodontal cyst ; Botryoid odontogenic cyst ; Jaw cyst ; Cytokeratins
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Abstract The botryoid odontogenic cyst (BOC) is considered a rare multilocular variant of the lateral periodontal cyst. The origin of the BOC can be seen in aberrant odontogenic tissue. The BOC is found especially in the premolar region of the mandible, as well as in the frontal region of the maxilla of patients aged between 60 and 70 years. Most of the 11 published articles of BOC have shown high rates of recurrence. Histopathologically the BOC is marked by multilocular cysts lined by a thin, nonkeratinized epithelium. Clusters of glycogen-rich epithelial cells may be noted in nodular thickenings of the cyst lining. For the clinician, the differentiation of the BOC from the keratocyst and ameloblastoma is ¶relevant. One case of a large BOC (65-year-old male, BOC regio 33–45, diameter 5 cm, radiographically and histologically multilocular) is presented with a review of the literature, including the therapeutic management, and the possible diagnostic criteria are discussed. The immunohistochemically determined expression of cytokeratin (CK) 13 implicates the histogenetic origin of the BOC from the squamous epithelium of the oral cavity and excludes the origin from the small salivary glands. The expression of CK 19 and the lack of expression of p53, as well as the higher proliferation rate of the basal epithelial cell layer by the BOC, may be useful for distinction between the keratocyst.
    Notizen: Zusammenfassung Die botryoide odontogene Zyste (BOC) ist eine seltene multilokuläre Variante der lateralen parodontalen Zyste. Sie entsteht aus versprengten odontogenen Zellanteilen. Die BOC tritt besonders häufig im Prämolarenbereich des Unterkiefers und im anterioren Oberkiefer bei Patienten zwischen der 6. und 7. Lebensdekade auf. Unter den bisher publizierten 11 Arbeiten zeigt sich eine hohe Rezidivhäufigkeit. Histologisch ist die BOC durch multilokuläre Zysten mit einem isomorphen Epithel gekennzeichnet. Dieses zeigt fokale plaqueähnliche Verdickungen durch Gruppierungen glykogenreicher Plattenepithelzellen. Für den Kliniker ist die Abgrenzung zur Keratozyste bzw. zum Ameloblastom differentialdiagnostisch bedeutsam. Ein Zufallsbefund einer besonders großen BOC (65 Jahre, männlich, BOC-Regio 33–45, 5 cm Durchmesser, radiologisch und histologisch multilokulär) wird inklusive therapeutischem Vorgehen und Literaturübersicht vorgestellt, mögliche Diagnosekriterien werden diskutiert. Der immunhistochemische Nachweis der Expression von CK13 impliziert eine histogenetische Ableitung der BOC vom oralen Plattenepithel und spricht gegen eine Ableitung von den Speicheldrüsen. Die Expression von CK19 und die fehlende Expression des p53 sowie die hohe Proliferation in der Basalzellschicht durch die BOC können zur Abgrenzung von der Keratozyste benutzt werden.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 9
    Digitale Medien
    Digitale Medien
    Springer
    Fresenius' journal of analytical chemistry 367 (2000), S. 679-685 
    ISSN: 1432-1130
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Abstract Optimum experimental factors were determined for the analytical determination of Al, Cd, Fe, Pb, and Zn by ICP atomic emission spectrometry. Based on systematically determined factor levels, working conditions were found that gave similiar, and sometimes better results compared with the hitherto used levels of factors. All measurements were performed with a sampling time of 150 ms as often used in routine analysis in the laboratory. This optimization resulted in a reduced outer plasma gas flow from 15 L/min argon to 12 L/min without any relevant changes of the achievable detection limits. A serious problem was that only one analytical line of Al could be used. A comparison with the lower limit of application (comparable with the detection limit) from German directive DIN 38406, part 22 ([1]), showed that the detection limits of Al and Fe are superior, whereas for Cd there was only little improvement. The detection limits of Zn and especially Pb are always higher than the lower range of application under these conditions. Therefore, the use of two device-parameter sets for hard and soft lines, respectively, is strongly suggested. Maps with the observed signal-to-noise-ratios were systematically acquired for each element analyzed in connection with different strategies for optimum search.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 10
    Digitale Medien
    Digitale Medien
    Springer
    The European physical journal 14 (2000), S. 383-394 
    ISSN: 1434-6036
    Schlagwort(e): PACS. 02.50.Ey Stochastic processes - 05.40.Jc Brownian motion - 89.90.+n Other topics of general interest to physicists (restricted to new topics in section 89)
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract: Non-equilibrium phenomena occur not only in the physical world, but also in finance. In this work, stochastic relaxational dynamics (together with path integrals) is applied to option pricing theory. Equilibrium in financial markets is defined as the absence of arbitrage, i.e. profits “for nothing”. A recently proposed model (by Ilinski et al.) considers fluctuations around this equilibrium state by introducing a relaxational dynamics with random noise for intermediate deviations called “virtual” arbitrage returns. In this work, the model is incorporated within a martingale pricing method for derivatives on securities (e.g. stocks) in incomplete markets using a mapping to option pricing theory with stochastic interest rates. The arbitrage return is considered as a component of a fictitious short-term interest rate in a virtual world. The influence of intermediate arbitrage returns on the price of derivatives in the real world can be recovered by performing an average over the (non-observable) arbitrage return at the time of pricing. Using a famous result by Merton and with some help from the path integral method, exact pricing formulas for European call and put options under the influence of virtual arbitrage returns (or intermediate deviations from economic equilibrium) are derived where only the final integration over initial arbitrage returns needs to be performed numerically. This result, which has not been given previously and is at variance with results stated by Ilinski et al., is complemented by a discussion of the hedging strategy associated to a derivative, which replicates the final payoff but turns out to be not self-financing in the real world, but self-financing when summed over the derivative's remaining life time. Numerical examples are given which underline the fact that an additional positive risk premium (with respect to the Black-Scholes values) is found reflecting extra hedging costs due to intermediate deviations from economic equilibrium.
    Materialart: Digitale Medien
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