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  • 2000-2004  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Analysis of differential gene expression supports a role for amyloid precursor protein and a protein kinase C substrate (MARCKS) in long-term memory (2003)
    Oxford, UK : Blackwell Science, Ltd
    European journal of neuroscience 17 (2003), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Previous work has identified the intermediate and medial part of the hyperstriatum ventrale (IMHV) as a region of the chick brain storing information acquired through the learning process of imprinting. We have examined in this brain region changes in expression of candidate genes involved in memory. Chicks were exposed to a rotating red box and the strength of their preference for it, a measure of learning, determined. Brain samples were removed ≈24 h after training. Candidate genes whose expressions were different in IMHV samples derived from strongly imprinted chicks relative to those from chicks showing little or no learning were identified using subtractive hybridization. The translation products of two candidate genes were investigated further in samples from the left and right IMHV and from two other brain regions not previously implicated in imprinting, the left and right posterior neostriatum. One of the proteins was the amyloid precursor protein (APP), the other was myristoylated alanine rich C kinase substrate (MARCKS). In the left IMHV the levels of the two proteins increased with the strength of learning. The effects in the right IMHV were not significantly different from those in the left. There were no effects of learning in the posterior neostriatum. This is the first study to relate changes in the amounts of MARCKS and APP proteins to the strength of learning in a brain region known to be a memory store and demonstrates that the systematic identification of protein molecules involved in memory formation is possible.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1460-9568.2003.02539.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Towards fully parallel aerospace simulations on unstructured meshes (2001)
    Bradford : Emerald
    Engineering computations 18 (2001), S. 347-376 
    Details
    ISSN: 0264-4401
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Technology
    Notes: A general philosophy is presented in which all the modules within the computational cycle are parallelised and executed on parallel computer hardware, thereby avoiding the creation of computational bottlenecks. In particular, unstructured mesh generation with adaptation, computational fluid dynamics and computational electromagnetic solvers and the visualisation of grid and solution data are all performed in parallel. In addition, all these modules are embedded within a parallel problem solving environment. This paper will provide an overview of these developments. In particular, details of the parallel mesh generator, which has been used to generate meshes in excess of 100 million elements, will be given. A brief overview will be presented of the approach used to parallelise the solvers and how large data sets are interrogated and visualised on distributed computer platforms. Details of the parallel adaptation algorithm will be presented. These parallel component modules are linked using CORBA communication to provide an integrated parallel approach for large scale simulations. Several examples are given of the approach applied to the simulation of large aerospace calculations in the field of aerodynamics and electromagnetics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/02644400110386984
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The simulation of electromagnetic scattering in piecewise homogeneous media using unstructured grids (2000)
    Springer
    Computational mechanics 25 (2000), S. 438-447 
    Details
    ISSN: 1432-0924
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  This paper presents a method for simulating, in the time domain, the scattering of electromagnetic waves in piecewise homogeneous media. The method employs an explicit Taylor–Galerkin approach, implemented on a general unstructured triangular grid, with the electric and magnetic fields approximated in a continuous piecewise linear fashion. All boundary and material interface conditions are weakly applied in an integral form, following a characteristic decomposition of the solution. A number of simple examples, for which exact scattering width distributions are available, are included to demonstrate the numerical performance of the proposed procedure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004660050491
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    Paper (German National Licenses)
    Fulltext
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