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  • 2000-2004  (7)
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Material
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    T cells in psoriasis (2003)
    Oxford, UK : Munksgaard International Publishers
    Experimental dermatology 12 (2003), S. 0 
    Details
    ISSN: 1600-0625
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0906-6705.2003.0156h.x
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    ‘The first bite of the cherry’ Intra-oral manipulation prior to the first bite in humans (2001)
    Oxford UK : Blackwell Science Ltd
    Journal of oral rehabilitation 28 (2001), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The breakdown of food in the mouth during mastication can be described in terms of two parameters: a breakage function, which describes the fragmentation of food after a bite, and a selection function which defines the probability of particle fracture. The non-zero value of the selection function depends on the manipulation of food particles by the tongue. Little, however, is known about this. As a first step, this study investigated the manipulation of wax sheets of differing sizes and shapes by the tongue after ingestion. It was found that subjects tended to orientate rectangular and square wax wafers so that the long axis of the particle was parallel to the tooth row, independent of the initial orientation given when they were introduced into the mouth. Circular wafers were randomly oriented relative to initial orientation. If this could be extrapolated to the start of mastication, then it suggests that the tongue tends to align food particles so that the post-canines produce close to the greatest surface area possible by fragmenting them along their longest axis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2842.2001.00732.x
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Abrasives in foods and their effect on intra-oral processing: a two-colour chewing gum study (2004)
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 31 (2004), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary  In this study we suggest that the presence of abrasives in food items lead to physiologic responses that reduce the amount of tooth loss because of abrasion. Subjects were presented with two pairs of two-colour chewing gum, one sample had 0·5 g of an abrasive powder added. Subjects were instructed to chew for 10 or 20 chewing strokes and then remove the gum. After removal the chewing gum was placed in a plastic bag and flattened. Each pair of gums was compared on the basis of the amount of mixing observed. In all cases the addition of the abrasive powder resulted in slower chewing and less mixing. Salivary flow rate increased from a resting value of 0·6 to 0·9 mL min−1 when stimulated by the non-abrasive gum to 1·1 mL min−1 with the abrasive gum. This difference was significant (P 〈 0·05). We conclude that when abrasive particles are detected in the mouth, less bolus manipulation is performed and more saliva is secreted. These responses would have the effect of reducing loss of tooth substance at the expense of reduced cominution of the food.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2842.2004.01328.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Bolus dimensions in normal chewing (2000)
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 27 (2000), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Samples of 17 different types of chewing gum weighing between 0·3 and 22 g were presented to eight subjects. After chewing the samples for between 20 and 100 strokes the boluses of gum were removed from the mouth and their length was measured. Bolus length increased with weight from 0·3 to 4 g, but remained constant between 4 and 18 g at which point it began to increase once more. The range of sizes associated with this plateau is similar to the range of sizes of natural bites with other foods.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2842.2000.00577.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Computer aided gnathosonic analysis: distinguishing between single and multiple tooth impact sounds (2000)
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 27 (2000), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Watt developed a classification of tooth contact sounds that distinguished between the short sharp, reproducible sounds heard when the teeth meet simultaneously and the dull prolonged, poorly reproducible sounds heard when tooth contacts are sequential. However, when a large occlusal prematurity, for instance a high restoration, is introduced, tooth contact sounds are also short sharp and highly reproducible. In this study, a method of distinguishing single from multiple tooth contact sounds is described, based on an analysis of the phase and amplitude of sounds detected by headphones placed over the ears.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2842.2000.00551.x
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Saliva tannin interactions (2000)
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 27 (2000), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Many plant foods contain tannins, compounds that bind proteins, such as mammalian enzymes. Although described as tasteless, tannins can be detected orally by their astringency. However, the actual mechanism of oral detection and the effect of tannins on mastication and swallowing have been little investigated. Here, we show from in vitro tests that tannic acid, a common standard in tests used to detect tannins, significantly reduces the lubricating qualities of human saliva both by decreasing its viscosity and increasing friction, both factors lending support to the notion that astringency is a tactile phenomenon. From the literature, it is clear that this effect depends on the presence of salivary proline-rich proteins (PRP). In a mammalian context, ingestion of tannin-rich foods in a species with salivary PRP will be signalled by interference with bolus formation during mastication while the increase in friction may also be detectable and lead to increased tooth wear if the signal is ignored. In a human context, cross-cultural preferences for tannin-rich beverages such as tea, coffee and red wine at the end of meals may be explained by reduction in adhesion of food particles to the oral mucosa allowing their rapid oral clearance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2842.2000.00578.x
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    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Biological therapies in the systemic management of psoriasis: International Consensus Conference (2004)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 151 (2004), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Psoriasis is a chronic, immune-mediated disorder that usually requires long-term treatment for control. Approximately 25% of patients have moderate to severe disease and require phototherapy, systemic therapy or both. Despite the availability of numerous therapeutic options, the long-term management of psoriasis can be complicated by treatment-related limitations. With advances in molecular research and technology, several biological therapies are in various stages of development and approval for psoriasis. Biological therapies are designed to modulate key steps in the pathogenesis of psoriasis. Collectively, biologicals have been evaluated in thousands of patients with psoriasis and have demonstrated significant benefit with favourable safety and tolerability profiles. The limitations of current psoriasis therapies, the value of biological therapies for psoriasis, and guidance regarding the incorporation of biological therapies into clinical practice are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.2004.06070.x
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    Paper (German National Licenses)
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