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  • 1
    Electronic Resource
    Electronic Resource
    Total Synthesis of Brevetoxin B. 1. First Generation Strategies and New Approaches to Oxepane Systems (1995)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 117 (1995), S. 10227-10238 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00146a008
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  • 2
    Electronic Resource
    Electronic Resource
    Sex difference of electromyogram of masticatory muscles and mandibular movement during chewing of food (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 24 (1997), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary The aim of this study was to investigate whether there were sex differences in the electro-myograms (EMG) of the masticatory muscles and in the mandibular movement of young adults when chewing food. Twenty subjects with normal dentitions were selected. The II test foods selected were all easily available in Japan. The results showed firstly that although there were no significant differences of chewing frequency between males and females, females chew food more slowly with less masticatory force and narrower mouth opening width than males; and secondly it appears that the chewing function in females is lower than in males.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2842.1997.tb00380.x
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  • 3
    Electronic Resource
    Electronic Resource
    Finite element analysis of the effect of vertical curvature on half-oval cast clasps (1999)
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 26 (1999), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: High stresses in half-oval cast clasps are the main causes of deformation or fracture. A vertical curvature in clasps is said to be effective in reducing stress. However, such claims lack scientific basis. The purpose of the present study was to evaluate stress and stiffness in a three-dimensional (3D) finite element analysis (FEA) model of clasps with different vertical curvatures, cross-sectional forms and tapers, and to clarify the effect of vertical curvature on the half-oval cast clasp. Circumferential clasp arms for the mandibular second premolar were analysed by 3D FEA. The clasp arms were approximated by curved cantilever beams with a half-oval cross-section around a cylinder. The radius of curvature was set at 4 mm and the angle subtended by the clasp arm was 120°. The clasp tip was set at a point 2 mm lower than the base. In the ‘No-taper’ half-oval clasp arm, stress increased and stiffness decreased with the increase in vertical curvature. In the shape of a preformed wax pattern (thickness/width=0·80, tip/base=0·70), stress and stiffness decreased slightly. In an ‘Original’ form (thickness/width=0·33, tip/base=0·80), vertical curvature had a very slight effect on stress and stiffness, and stress was the lowest. These findings suggest the superiority of the ‘Original’ form, with less stress and no effect of vertical curvature.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2842.1999.00422.x
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  • 4
    Electronic Resource
    Electronic Resource
    Unstable behavior of Ga atoms in ZnSe epitaxial layers (1997)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 82 (1997), S. 1196-1200 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Using ion-channeling methods, the thermal stability of crystallinity for heavily Ga-doped ZnSe epitaxial layers grown on GaAs (100) substrates was investigated. Some distinctive features were found: The crystallinity of as-grown heavily Ga-doped ZnSe is similar to that of undoped ZnSe. After thermal annealing at 450 °C, the crystallinity of Ga-doped ZnSe is degraded, although that of undoped ZnSe is not significantly changed. It is expected that doped Ga atoms are displaced from the regular lattice sites after annealing. The degree of this degradation depends on the crystallinity of the as-grown Ga-doped ZnSe itself. These results indicate the degradation of the crystallinity for Ga-doped ZnSe epilayers is mainly caused by the interaction between the doped Ga atoms and grown-in point defects in the epitaxial layers. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.365888
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  • 5
    Electronic Resource
    Electronic Resource
    Leucocytoclastic vasculitis associated with mixed cryoglobulinaemia and hepatitis C virus infection (1997)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 136 (1997), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Mixed cryoglobulinaemia is frequently associated with chronic hepatitis. We report a patient with mixed cryoglobulinaemia, hepatitis C virus (HCV) infection and palpable purpura. The skin manifestations were diagnosed as leucocytoclastic vasculitis in view of both the clinical appearance and the histological findings. In this study, we demonstrated the presence of IgG–class anti–HCV–antibody. HCV–RNA and IgA–class rheumatoid factor in the cryoprecipitate. These results suggest that the cryoglobulinaemia in this case was caused by aggregation of an immune complex comprised of HCV and anti–HCV antibody with IgA–type–rheumatoid factor, and that this led to a cutaneous vasculitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.1997.d01-1186.x
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  • 6
    Electronic Resource
    Electronic Resource
    Histological study of lectin binding in regenerated rat junctional epithelium (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 30 (1995), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We investigated the expression of carbohydrate residues in regenerated junctional epithelium (JE) cells histopathologically with lectin staining to clarify the mechanisms responsible for the changes in their expression in JE cells derived from residual oral epithelium. Curettage and root planing procedures were performed on the buccal gingival sulci of rat first lower molars, and JE and connective tissues were completely removed. The mandibles were resected after 12 h and 1, 2, 3, 4, 5, 7, 10 and 14 days, fixed with paraformaldehyde, decalcified with EDTA and embedded in paraffin. Serial sections were stained histochemically with four kinds of lectins (PNA, DBA, GS I, UEA I) to clarify the expression patterns of carbohydrate residues in regenerating epithelium. No binding of PNA or DBA was observed even when the regenerating epithelium was attached to the root surface, and they showed the same negative reactions as the basal cells of oral gingival epithelium (OGE). Positive reactions were, however, observed on the more stratified regenerating epithelium along the root surface. Positive reactions with GS I and negative reactions with UEA I were observed throughout the regeneration process, and these were the same as those observed in the basal cells of OGE. Therefore, we concluded that the basal cells and regenerated epithelium derived from OGE expressed the same carbohydrate residues. Futher-more, the expression of carbohydrate residues, one of the characteristics of JE, was related not only to the attachment to the tooth surface but also to changes of cell shape and cytoskeleton with stratification along the root surface.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1995.tb02128.x
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  • 7
    Electronic Resource
    Electronic Resource
    Preparation of Silicon Oxycarbide Ceramic Films by Pyrolysis of Polymethyl- and Polyvinylsilsesquioxanes (1999)
    Springer
    Journal of sol gel science and technology 16 (1999), S. 227-234 
    Details
    ISSN: 1573-4846
    Keywords: polysilsesquioxane ; precursor ; pyrolysis ; silicon oxycarbide ; ceramics ; films
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The sol-gel reactions of methyl- and vinyltrimethoxysilane under controlled conditions provided the corresponding polysilsesquioxanes and flexible thin films on further condensation of the precursors. Silicon oxycarbides containing a large amount of free carbon 58 mol% and 90 mol% were obtained in high yields 90 wt% on pyrolyzing the precursors of polymethyl-and polyvinylsilsesquioxane at 1400°C under N2 atmosphere, respectively. Moreover, pyrolytic polycondensation of polyvinylsilsesquioxane was found to give the silicon oxycarbide ceramic films without deformations and cracks. The composition and properties of films were investigated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008765103113
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  • 8
    Electronic Resource
    Electronic Resource
    Sol-Gel Preparation of Silica Films with Controlled Surface Morphology and Their Application to a Low Reflective Glass (1999)
    Springer
    Journal of sol gel science and technology 14 (1999), S. 175-186 
    Details
    ISSN: 1573-4846
    Keywords: sol-gel method ; silica film ; surface morphology ; porous ; low reflective glass
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Silica coating films with various surface morphologies, such as flat, porous (with deep pores), concave-convex (with hills and valleys), and convex (with hills on flat plane) structure were prepared from a mixture of two kinds of sols derived from polymerized tetraethoxy-silane (TEOS) and methyltriethoxysilane (MTES). Different surface morphologies were obtained by varying the molar ratio r = MTES/TEOS of the coating solution. The surface was flat for r less than 2.5, porous for 2.5 ≤ r 〈 5, concave-convex for 5 ≤ r 〈 7.5, convex for 7.5 ≤ r 〈 13, and again flat for r larger than 13. For 2.5 ≤ r 〈 5, the apparent refractive index of the silica film with porous morphology was decreased to 1.23 by selecting the solvent and by controlling the relative humidity of the coating atmosphere and the heat treatment temperature. Coating of glass with silica films of low refractive index of 1.23 led to the low reflective glasses with visible light reflectance Rvis of less than 0.2%.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008738117124
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  • 9
    Electronic Resource
    Electronic Resource
    A phase II study of cisplatin, oral administration of etoposide, OK-432 and radiation therapy for inoperable stage III non-small cell lung cancer (1998)
    Springer
    International journal of clinical oncology 3 (1998), S. 365-369 
    Details
    ISSN: 1437-7772
    Keywords: Stage III non-small cell lung cancer ; CDDP ; VP-16 ; Conventional radiotherapy ; Concurrent chemoand radiotherapy ; Accelerated proliferation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background. This study was designed to evaluate the feasibility and efficiency of giving cisplatin, etoposide, and OK432 concurrently with conventional radiotherapy (RTx) for patient's with inoperable stage III, based on the TNM classification according to the International Union against Cancer staging system for lung cancer (1987) non-small cell lung cancer (NSCLC). Methods. From January 1992 to December 1994,31 patients with cytologically or histologically confirmed stage III NSCLC were treated with RTx, to a total dose of 56–64 Gy, with concurrent daily oral administration of etoposide (25mg) and cisplatin (20mg) for 5 days during the third or fourth week from the start of RTx. The subcutaneous injection of 1 or 2 KE of OK-432, three times a week, for the duration of radiotherapy also started from the beginning of RTx. Results. The number of eligible patients was 29 (26 men and 3 women). Their mean age was 66 years (range, 55–77 years). Six patients had an Eastern Cooperative Oncology Group performance status (PS) of 0; 15, 1; 8; 2. Three were stage IIIA, and 26, stage ITIB. Histologically, 2 had adenocarcinoma, 23, squamous cell carcinoma, and 4, large cell carcinoma. In 27 of the 29 patients, the RTx schedule was completed. There were no treatment-related deaths. Grade 4 toxicity (according to World Health Organisation criteria) leukopenia (700/μl was observed in 1 patient. The response rate was 79% and the median survival was 17 months. Survival rates at 1, 2 and 3 years were 62%, 31%, and 21%, respectively. The local failure rate was 51%. Conclusion. The combination of cisplatin, etoposide, and K-432, given concurrently with conventional RTx is feasible and effective for inoperable stage III NSCLC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00539214
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  • 10
    Electronic Resource
    Electronic Resource
    Pedicled free flap for burn scar contracture of a hand (1998)
    Springer
    European journal of plastic surgery 21 (1998), S. 103-105 
    Details
    ISSN: 1435-0130
    Keywords: Key words Post-burn contracture ; Free tissue transfer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The treatment of a severe post-burn contracture of the left hand is presented. A free scapular flap was transplanted to the inguinal area and then used to release the contracture in the manner of a pedicled groin flap. The advantages of this method are that it can be utilized regardless of the condition of the recipient site, and the major vessels of the hand remain intact.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002380050038
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