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  • 1995-1999  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Changes in mean trabecular orientation in the medial condyle of the proximal tibia in osteoarthritis (1995)
    Springer
    Calcified tissue international 57 (1995), S. 69-73 
    Details
    ISSN: 1432-0827
    Keywords: Trabecular orientation ; Osteoarthritis ; Medial tibial condyle ; Subchondral sclerosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract In osteoarthritis of the knee, degenerative changes occur in the articular cartilage and underlying subchondral bone, particularly of the medial tibial condyle. Cancellous bone sclerosis that accompanies osteoarthritis is not only the result of an increase in bone volume fraction but also a change in trabecular structure. In a comparison with agematched controls (n=4), osteoarthritis (n=11) demonstrated a significant (P≤0.05) increase in bone volume fraction and trabecular thickness. Overal trabecular orientation in the osteoarthritic group was more vertical or perpendicular to the articular surface than the control group (P≤0.05) especially in the trabeculae of the cancellous bone layer closest to the articular surface. These alterations in trabecular bone structure could have significant consequences for the mechanical properties of osteoarthritic bone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00299000
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Ochronotic arthropathy: case report and review of the literature (1999)
    Springer
    International orthopaedics 23 (1999), S. 122-125 
    Details
    ISSN: 1432-5195
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé  L’ochronose est une manifestation musculo-squélettique de l’alkaptonurie dûe à un désordre métabolique qui accompagne diverses anomalies systemiques et associé au depôt de pigments acides homogénetiques dans les tissues congonctifs. Nous decrivons deux cas d’ arthopathie presentant des douleurs progressives et des symptômes de dégénerescence avancée de la region lombo-sacrée. Cet article inclut la bibliographie, les diagnostics differentiels et le traitement de cette maladie rare. La therapie classique est toujours d’ actualité, mais l’implantation de prothéses peut être offerte dans des cas d’ atteintes severes des articulations majeures.
    Notes: Abstract  Alkoptonuria is an inherited metabolic disorder which is associated with various systemic abnormalities and related to the deposition of homogentisic acid pigment in connective tissues. These pigmentary changes are termed ”ochronosis”. We describe two patients with ochronotic arthropathy who presented with progressive and advanced degenerative changes in the lumbo-sacral spine. The literature, differential diagnosis and management of this rare condition are reviewed in this article. Management is usually conservative, but replacement surgery may be offered for severely affected major joints.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002640050325
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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