ISSN:
1432-1920
Keywords:
Key words Acquired immunodeficiency syndrome (AIDS)
;
Brain
;
infection
;
Magnetic resonance imaging
;
Computed tomography
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract We sought to determine the value of follow-up CT and MRI in patients with acquired immunodeficiency syndrome (AIDS) and progressive multifocal leukoencephalopathy (PML). We reviewed 50 CT and 19 MRI examinations performed in 21 biopsy- or autopsy-proven cases of PML; 17 patients had follow-up examinations (mean time 5.9 weeks). The radiological examinations were correlated with pathological findings at autopsy. On initial imaging studies, 73 lesions were found. On follow-up, the most striking feature was rapid progression in both size and number of the lesions (from a mean of 3.2 to 6.9 per patient). One third of the patients showed increasing mass effect. A central area suggesting necrosis, of variable size, was found in 12/16 patients. Autopsy revealed macroscopic necrotic changes in the lesions in 11/16 patients.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s002340050478
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