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  • 1
    Electronic Resource
    Electronic Resource
    Enhanced in-plane anisotropy of Tb–Fe thin films by Sm addition (1999)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 85 (1999), S. 6244-6246 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Effects of Sm on the magnetic and magnetostrictive properties of Tb–Fe thin films are investigated. Four alloy systems, RxFe100−x (R=Tb+Sm) with x=39.8, 41.9, 43.7, and 45.8, are examined with Sm content varied from 0 (Sm free) to 2.2 at. %. In-plane anisotropy is found to be enhanced by the addition of Sm and the strongest in-plane anisotropy occurs in the Sm content range of 1 to 2 at. % depending on R content. At low magnetic fields of 1000 Oe and below, magnetostriction increases significantly with increasing Sm content, and reaches a maximum at an intermediate Sm content where well-developed in-plane anisotropy is observed. At higher magnetic fields of 3000–5000 Oe, however, no substantial improvement of magnetostriction occurs with the addition of Sm. The Sm content dependences of magnetization and coercive force are also examined. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.370234
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  • 2
    Electronic Resource
    Electronic Resource
    T-cell receptor Vβ usage by lesional lymphocytes in oral lichen planus (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 26 (1997), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: To determine whether the T-cell inflammatory infiltrate in oral lichen planus (OLP) represents a selective activation and expansion of a limited repertoire of T-cell receptor (TCR) specific T-cells. Vβ gene expression was investigated in lesional T-lymphocytes in OLP. A reverse transcriptase-polymerase chain reaction (RT-PCR) technique was used to amplify the 24 major Vβ gene sub-families of infiltrating mucosal lymphocytes and peripheral blood mononuclear cells (PMNC) in seven patients with reticular OLP and four healthy control patients. Specificity of amplified products was confirmed by Southern blotting with a Cp internal probe. TCR Vβ usage by lesional T-cells in OLP was markedly heterogeneous 5–23 Vβ sub-families). In 6/8 patients with OLP. Vβ usage was restricted with 〈inlineGraphic alt="leqslant R: less-than-or-eq, slant" extraInfo="nonStandardEntity" href="urn:x-wiley:09042512:JOP105:les" location="les.gif"/〉20/25 sub-families detected: only one of the Vβ sub-families (Vβ 8) was present in all of the OLP patients demonstrating TCR Vβ restriction. In contrast. TCR Vβ usage was unrestricted in PMNC from OLP patients and controls (〈inlineGraphic alt="leqslant R: less-than-or-eq, slant" extraInfo="nonStandardEntity" href="urn:x-wiley:09042512:JOP105:les" location="les.gif"/〉23/25 sub-families detected). In three patients, certain Vβ sub-families (Vβ13, Vβ14 & Vβ15) were present in the lesional T-cell population but were under-represented in PMNC. These results suggest a selective Vβ gene usage by lesional infiltrating T-cells in oral lichen planus. The non-uniformity of Vβ restriction in lesional T-cells does not support the concept of a common superantigen in OLP and reflects the heterogeneity of the disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1997.tb00031.x
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  • 3
    Electronic Resource
    Electronic Resource
    T cell receptor Vβ repertoire of tumour-infiltrating lymphocytes in oral squamous-cell carcinoma (1996)
    Springer
    Cancer immunology immunotherapy 42 (1996), S. 69-70 
    Details
    ISSN: 1432-0851
    Keywords: Key words T cell receptor ; TIL ; Oral squamous cell carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Oral squamous cell carcinoma (OSCC) are frequently infiltrated by tumour infiltrating lymphocytes (TILs) which may demonstrate specific anti-tumour cytotoxicity. We have used a panel of family-specific primers in reverse-transcriptase (RT)-polymerase chain reactions (PCR) to determine the TCR Vβ repertoire of TILs in the primary and metastatic tumours in patients with OSCC. We observed a diverse and heterogeneous usage of the TCR Vβ genes by TILs in the primary tumours, a scenario not unlike normal oral mucosal lymphocytes. In one patient with a longstanding history of OSCC, the repertoire was restricted. Restricted TCR Vβ gene usage also occurred in TILs of metastatic tumours. Within individual patients, discrepancies of TCR Vβ gene usage were also observed between TILs in the primary OSCC and those in metastatic lymph nodes. Work is ongoing to determine the clonality and functional significance of these TILs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002620050253
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  • 4
    Electronic Resource
    Electronic Resource
    Molecular characterisation of tumour infiltrating lymphocytes in oral squamous cell carcinoma (1998)
    Springer
    Cancer immunology immunotherapy 46 (1998), S. 34-40 
    Details
    ISSN: 1432-0851
    Keywords: Key words OSCC ; TILs ; T cell clonal expansion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Oral squamous cell carcinoma (OSCC) is often associated with a lymphocytic infiltrate that is believed to represent an in vivo immune reaction to the tumour cells. In this study, the tumour-infiltrating lymphocytes (TIL) associated with primary OSCC were characterised molecularly in six newly-diagnosed patients to determine the nature of the immune response to the primary tumour. The primary tumours in three of the six patients were associated with a moderate to dense CD8+ T cell infiltrate whilst the cellular infiltrate in the other primary tumours was sparse. The CD3+ T cells were also HLA-DR+. In all cases, there were few CD56+ cells, suggesting that TIL were predominantly T cells bearing the α/β T cell receptors (TCR). The TCR Vβ repertoire of TIL in these six cases was analysed. TCR Vβ gene usage by TIL was heterogeneous. A restricted usage of TCR Vβ genes by TIL was evident in two tumours associated with a dense CD3+ T cell infiltrate. In one of these, there was histological evidence of tumour cell destruction by TIL. Further analysis of the predominant TCR Vβ gene family used by TIL in this individual showed a unique in-frame nucleotide sequence in 100% of the transcripts. This recurrent transcript was not detected in the peripheral blood of this patient, indicating a local T cell clonal expansion in the vicinity of the tumour. Overall, these results suggest that activation and clonal expansion of T cells occurs and may play a role in local tumour destruction in OSCC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002620050457
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  • 5
    Electronic Resource
    Electronic Resource
    The magnetic properties of Fe-based amorphous ribbons coated with various oxides using the sol–gel process (1997)
    Springer
    Journal of materials science 32 (1997), S. 3219-3225 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The metal oxides MgO, BaO, Al2O3, SiO2, MgO–Al2O3, CaO–Al2O3, SrO–Al2O3, BaO–Al2O3 and MgO–SiO2 have been coated onto ribbons of the Fe-based amorphous alloy Metglas 2605S3A using a sol–gel process. The effects of the surface coating on the magnetic properties of the alloy are investigated. The d.c. hysteresis loop for ribbons coated with MgO and MgO–Al2O3 is more square shaped than that for the uncoated ribbon. For ribbons coated with BaO, SrO–Al2O3 and BaO–Al2O3 it is more inclined than for the uncoated ribbon. Significant differences in the frequency dependence of the effective permeability are observed that depend on the nature of the coated oxides. The core loss is also affected by the coating. These results may be explained in terms of a stress induced by the coating and the modification of the domain structure via elastic and/or magnetoelastic interactions. It is thought from the magnetoelastic interactions that the MgO and MgO–Al2O3 coatings induce tensile stresses whilst those of BaO, SrO–Al2O3 and BaO–Al2O3 induce compressive stresses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018615104519
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  • 6
    Electronic Resource
    Electronic Resource
    Morphological and molecular variations in the epiphytic CAM fern Pyrrosia piloselloides (1998)
    Springer
    Biologia plantarum 41 (1998), S. 281-285 
    Details
    ISSN: 1573-8264
    Keywords: frond morphology ; genetic variation ; RAPD DNA markers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Variation in shape and size of mature sterile fronds of the epiphytic fern, Pyrrosia piloselloides (L.) Price, was observed. These morphological differences were also linked to genotypic variations of the different fern populations studied. Genetic polymorphism in different populations of P. piloselloides was investigated using random amplified polymorphic DNA markers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1001843403536
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