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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 56 (1995), S. 355-358 
    ISSN: 1432-0827
    Keywords: Anthropometry ; Archeology ; Bone density ; Densitometry ; Osteoporosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract We studied the most complete skeletons found in an excavation from the 14th and 15th century in central Stockholm. One hundred eighty-seven were from men and 156 from women: 241 individuals were estimated to be between 20 and 39 and 102 between 40 and 59 years old at death. We examined the bones radiographically and by dual photon absorptiometry. The bone mineral density (BMD) was similar to the finding in North America and Northern Europe today as was the relationship between men and women. However, there appeared to be a higher diaphyseal bone density in the lower extremities, especially in men. The femur score was higher and the BMD of the femoral and tibial shafts was higher than today. In the upper extremities the diaphyseal bone density was lower. Meema's index, as well as the metacarpal score, was smaller than in individuals in this century and the BMD of the humeral shaft was also lower than seen today. Overall, the metaphyseal bone density was similar to what we now consider normal; i.e., the mean BMD of the femoral neck was 0.96 g/cm2 in men and 0.90 g/cm2 in women and of the distal radius 0.43 and 0.32 g/cm2, respectively. The low diaphyseal density and in the upper extremities may be related to the nutritional status, whereas the greater need for walking and standing in the 14th and 15th century might have led to the high diaphyseal density in the lower extremities. There was no evidence of bone loss after 40 years of age in either sex in our study. The average expected lifespan for an adult individual was less than 50 years and we suggest that the relatively high bone density in the older age group may be due to selection of the most physically fit. The activity pattern, therefore, may be considered the most important determinant for the differences.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International orthopaedics 20 (1996), S. 7-11 
    ISSN: 1432-5195
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé. Nous avons étudié 70 patients après remplacement de la hanche par la prothèse de Lord non-cimenté qui a un corps macrostructuré relativement long. La durée de temps de contrôle était de 9,5 ans. Nous avons comparé les radiographies à une année post-opératoire avec celles obtenue après cinq ans ainsi que les radiographies prises aux derniers contrôles. Vingt-cinq patients (36%) avait une douleur de la cuisse, décrite comme profonde ou superficielle, en relation avec l’activité. Quarante-quatre patients avait un niveau d’activitéélevé (classe de fonction 5 et 6 selon Merle d’Aubigné et Postel). Parmi ces derniers, les patients souffrant de douleurs de la cuisse ont perdu moins d’os cortical proximal en comparaison des patients sans douleur de la cuisse (p 〈0.05). Le premier groupe montrait aussi plus de formation osseuse corticale distale (p 〈0.05). Les patients qui souffraient de douleurs de la cuisse montraient plus souvent des liserés radiographiques incomplets au niveau du milieu du corps de prothèse après cinq années (p 〈0.05), ce qui indiquait probablement un mouvement élastique de l’os plus prononcé par rapport à la prothèse. D’autre part la présence de liserés était en relation directe avec l’augmentation de la taille de l’os cortical après cinq années (p 〈0.01). L’évolution de l’épaisseur corticale a continué après cinq années à tous les niveaux, le sommet de la prothèse excepté (p 〈0.01). Ces faits suggèrent que le mouvement élastique relatif de l’interface pouvait causer la douleur et contribuer au remodelage du femur après remplacement non-cimenté de la hanche.
    Notes: Summary. We studied 70 patients after uncemented hip replacement with the Lord prosthesis which has a relatively long, completely macrotextured stem. The mean follow up was for 9.5 years. We compared radiographs at one year after operation, at 5 years and at the last follow up. Twenty-five patients (36%) had deep or circumferential pain in the thigh. Of the 44 who were most active at 5 years those with thigh pain had less proximal cortical loss than those without (p 〈0.05), most cortical bone formation distally and most often had incomplete radiolucent lines at the mid-stem level, perhaps indicating more elastic displacement of the bone relative to the prosthesis. The presence of radiolucent lines correlated with the increase in cortical width at 5 years (p 〈0.01). Cortical remodelling continued after 5 years at all levels except at the tip (p 〈0.01). The relative elastic displacement at the interface could cause pain and may contribute to the pattern of bone remodelling in the femur after uncemented hip replacement.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0951-4198
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: A fused-silica capillary high-performance liquid chromatography column (i.d. 0.25 mm) packed with octadecylsilane-bonded silica has been used on-line with continuous-flow negative-ion fast-atom bombardment (FAB) mass spectrometry for the separation and structural analysis of series of fatty acids and arachidonic acid metabolites derivatized with 4-aminobenzenesulphonic acid. Negative-ion FAB spectra of the derivatized lipids showed strong [M—H]- pseudomolecular ions. Collision-induced dissociation of these anions produced structurally informative daughter ions, arising from charge-remote fragmentations.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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