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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 69 (1998), S. 1622-1628 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A very compact, vacuum compatible charge coupled device (CCD) camera has been developed for vacuum ultraviolet and soft x-ray imaging spectroscopy. It can house any CCD frame format and two of them have been selected: 385×576 pixels, suitable for normal incidence spectroscopy (300–2500 Å), and 256×1024 pixels, for grazing incidence applications (5–300 Å). Owing to its small and lightweight package, it can be placed at the focus of vacuum spectrometers. A new concept cooling system is based on a three stage thermoelectric cooler in thermal connection with the CCD through a 30-cm-long flexible conductor, allowing the detector to have stress-free movements along the focal plane and a constant temperature. The camera head has been designed to achieve a high cooling efficiency, thus the CCD can be operated at −40 °C. This detector is well suited for applications that require high sensitivity and signal to noise ratio, wide dynamic range, good spatial and spectral resolutions. In addition, it overcomes the limits of fixed detectors and lets the optical performances of the spectrometer remain unchanged. The CCD camera has been tested during an experiment of laser produced plasma spectroscopy and some preliminary results are reported. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-5233
    Keywords: Key words Unclassifiable diabetes ; Islet cell antibodies ; C-peptide ; Soluble CD8 antigen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To evaluate the predictive factors of insulin requirement in newly diagnosed patients with unclassifiable diabetes, 54 consecutive patients, aged less than 35 years, were prospectively followed for 3 years or more. At entry, haemoglobin HbA1c, basal and stimulated C-peptide concentrations, HLA phenotype, islet cell antibodies (ICA) status, and serum levels of soluble CD8 antigen (sCD8) were evaluated. After a median time of 9 (range 2–32) months, 31 patients (group 1) required insulin therapy, whereas 23 patients (group 2) remained non-insulin-requiring after 36 months. Group 1 patients were younger (P〈0.05) and had higher HbA1c and sCD8 serum levels (P〈0.0001, respectively), a higher frequency of ICA positivity and of HLA DR3 and/or DR4 phenotype (P〈0.005 and P〈0.0001, respectively), and lower C-peptide concentrations (P〈0.005 and P〈0.0001, basal and stimulated, respectively) than group 2. The sensitivity, specificity, positive and negative predictive value, and overall accuracy for the subsequent insulin requirement were: sCD8 serum levels (〉737 U/ml), 100%, 65%, 79%, 100% and 85%, respectively; stimulated C-peptide (〈0.60 nmol/l), 71%, 96%, 96%, 74% and 81%, respectively; and ICA positivity (〉20 JDFU), 45%, 91%, 87%, 55% and 65%, respectively. Thus, higher sCD8 serum levels, low stimulated C-peptide concentrations and ICA positivity are the most powerful predictors of subsequent recourse to insulin therapy in young, newly detected patients with unclassifiable diabetes.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-5233
    Keywords: Unclassifiable diabetes ; Islet cell antibodies ; C-peptide ; Soluble CD8 antigen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To evaluate the predictive factors of insulin requirement in newly diagnosed patients with unclassifiable diabetes, 54 consecutive patients, aged less than 35 years, were prospectively followed for 3 years or more. At entry, haemoglobin HbAlc, basal and stimulated C-peptide concentrations, HLA phenotype, islet cell antibodies (ICA) status, and serum levels of soluble CD8 antigen (sCD8) were evaluated. After a median time of 9 (range 2–32) months, 31 patients (group 1) required insulin therapy, whereas 23 patients (group 2) remained non-insulin-requiring after 36 months. Group 1 patients were younger (P〈0.05) and had higher HbAlc and sCD8 serum levels (P〈0.001, respectively), a higher frequency of ICA positivity and of HLA DR3 and/or DR4 phenotype (P〈0.005 andP〈0.0001, respectively), and lower C-peptide concentrations (P〈0.005 andP〈0.0001, basal and stimulated, respectively) than group 2. The sensitivity, specificity, positive and negative predictive value, and overall accuracy for the subsequent insulin requirement were: sCD8 serum levels (〉737 U/ml), 100%, 65%, 79%, 100% and 85%, respectively; stimulated C-peptide (〈0.60 nmol/l), 71%, 96%, 96%, 74% and 81%, respectively; and ICA positivity (〉20 JDFU), 45%, 91%, 87%, 55% and 65%, respectively. Thus, higher sCD8 serum levels, low stimulated C-peptide concentrations and ICA positivity are the most powerful predictors of subsequent recourse to insulin therapy in young, newly detected patients with unclassifiable diabetes.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part B: Polymer Physics 33 (1995), S. 1723-1730 
    ISSN: 0887-6266
    Keywords: high density polyethylene ; hydrogenated oligo(cyclopentadiene) ; blends ; phase structure ; stress-strain ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The influence of hydrogenated olio(cyclopentadiene) (HOCP) on tensile mechanical properties of its blends with high density polyethylene (HDPE) has been studied at 20, 80, and 100°C. The nominal stress-strain curves performed at 20°C indicate an increase of the modulus and a conspicuous decrease of the ultimate properties increasing the HOCP content in the blend. Blends with HOCP content 〉 20%-wt are found to be very fragile at 20°C. These behaviors have been related to the presence of the HOCP-rich phase that has the glass transition at about 55°C. At 20°C the HOCP oligomers act as a hardener for the HDPE. The nominal stress-strain curves performed at 80 and 100°C show a strong decrease of the modulus (compared to the value at 20°C), plastic deformation for all the blends tested, and rupture of HDPE and blend samples at the beginning of the cold-drawing. Moreover, the modulus and the ultimate parameters are found to decrease with the composition. The behaviors at 80 and 100°C have been related to several factors: the higher mobility of HDPE molecules at these temperatures compared to that at 20°C; the HOCP-rich phase that is at temperatures higher than its glass transition, and so it acts as a plasticizer for the HDPE; and the decreases of crystallinity and number of entanglements when the HOCP is added to the HDPE component. ©1995 John Wiley & Sons, Inc.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
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