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  • 1
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0495
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Groundwaters from crystalline and metamorphic rocks (hardrocks) and from Quaternary deposits, i.e., alluvial and glacial deposits (softrocks) from the counties of Nord-Trøndelag and Sør-Trøndelag were analyzed for major and minor elements and ions including fluoride. The median concentration of F− in water from the hardrock aquifers is 0.28 mg/l (14.7 μeq/l) in contrast to water from softrock aquifers in which it is found to be 0.05 mg/1 (2.6 μeq/l). More importantly, ca. 15% of the locations where water was abstracted from hardrock wells contain 1.5 mg/l (78.9 μeq/l) F− or more. Thus, 15% of all hardrock wells returned F− results that are at or above the maximum recommended value for drinking water. Of the softrock wells, none are above 1 mg/l. Geologists would normally expect higher F−contents in groundwaters derived from acid rocks, e.g., in granitic or gneissic areas. When comparing the host lithology with the observed F−contents, however, no clear relationship between F− content and lithology is visible. The highest observed F− values actually occur in gneissic host rocks. However, wells drilled in amphibolites/greenstones, mica schists, calcareous rocks, and sedimentary rocks all returned some analytical results above 1.5 mg/l F−. These results suggest that all hardrock wells drilled should be tested for F− and the users informed about the results and advised to take any necessary precautions. When applying the recently proposed Norwegian drinking water limits to our data, 51% of all softrock well waters and 56% of all hardrock well waters are unfit for consumption without prior treatment, although we analyzed only for about half of the proposed elements/parameters. This result seriously questions the concept of fixed action levels—many of them with totally unproven health implications—for so many parameters/elements for hardrock groundwaters.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0495
    Keywords: Key words ICP-MS laser ablation ; Tree-ring profiles ; Heavy metals ; Pollution history
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  Laser ablation ICP-MS analysis of tree rings provides a rapid and sensitive method for investigating element concentrations and fluctuations in trees along time profiles. Time profiles obtained from pine and birch trees from a strongly polluted area in northwest Russia and a slightly polluted area at the Norwegian-Russian border show that single trees behave rather individualistically in terms of heavy metal contents as observed in the yearly growth rings. The obtained profiles can not be linked to the pollution history of the area. No correlation between pollution levels of the soils and observed metal content in tree rings can be established.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-0495
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  Top and bottom samples of overbank sediments were collected at 43 sites within a 12 000 km2 area around the nickel smelter in Nikel and the ore roasting plant at Zapoljarnij, in northwestern Russia. In addition, three detailed overbank profiles were sampled in 10-cm sections from three catchments representing different levels of pollution. All samples were analysed for more than 30 elements by ICP-AES following aqua regia extraction. Results obtained show that overbank sediments represent natural (geogenic) background levels rather well. Although the major pollutants (Co, Cu, Ni and S) are strongly enriched at some places close to industry, overbank sediment is not especially well suited for mapping the extent of airborne contamination in the area. Co, Cu, Ni and S are mobile within the profile collected from the most polluted catchment.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 73 (1995), S. 133-140 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Biological cybernetics 73 (1995), S. 123-128 
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Notes: Abstract.  We introduce a dynamical model for automatic vergence eye movement control. In connection with our dynamical system of binocular model neurons that solves the correspondence problem of stereo-vision, we present a complete model for stereo-vision. Our automatic vergence eye movement control adjusts an image segment, which is of momentary interest to the observer. The adjustment is done in such a way that we only need to define a disparity search range of minimal extension. Recently, a new method of encoding (3D) three-dimensional information in 2D pictures was designed in the form of computer-generated patterns of colored dots. At first glimpse, these so-called autostereograms appear as structured but meaningless patterns. After a certain period of observation, a 3D pattern emerges suddenly in an impressive way. Applying our algorithm to autostereograms, we find a fully satisfactory agreement with the multivalent perception experienced by humans. As in nature, in our model the phase transition between the initial state and the 3D perception state takes place in a very short time. Our algorithm is very robust against noise, and there is no need to interpolate a sparse depth map.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 111 (1999), S. 3349-3356 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: We revisit the far from equilibrium escape problem across a fluctuating potential barrier that is driven by asymmetric, unbiased dichotomous noise. Our closed analytical solution for arbitrary noise strengths reveals new aspects of the so-called "resonant-activation" effect and leads to interesting implications regarding far from equilibrium or externally controlled chemical reaction processes. Specifically, a genuine asymmetry-induced variant of resonant activation within the constant intensity scaling scheme is discovered, and a new possibility to manipulate reaction rates and yields, as well as the balance between reactants and products, is put forward. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 772 (1995), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Immunological reviews 172 (1999), S. 0 
    ISSN: 1600-065X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary: The concept of distinct endogenous and exogenous pathways for generating peptides for MHC-I and MHC-II-restricted presemation to CD4+ or CD8+ T cells fits well with the bulk of experimental data. Nevertheless, evidence is emerging for alternative processing pathways that generate peptides for MHC-I-restricted presentation. Using a well characterized, particulate viral antigen of prominent medical importance (the hepatitis B surface antigen), we summarize our evidence that the efficient, endolysosomal processing of exogenous antigens can lead to peptide-loaded MHC-I molecules. In addition, we describe evidence for endolysosomal processing of mutant, stress protein-bound, endogenous antigens that liberate peptides binding to (and presented by) MHC-I molecules. The putative biological role of alternative processing of antigens generating cytotoxic T lymphocyte-stimulating epitopes is discussed.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1600-065X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary: A non-human primate model for acquired immunodeficiency syndrome (AIDS), the simian immunodeficiency virus (SIV)-infected rhesus monkey, was used to explore the role of the AIDS virus-specific cytotoxic T-lymphocyce (CTL) response in disease pathogenesis. This CTL response was measured using the major histocompatibility complex (MHC) class I/peptide tetramer technology, large numbers of tetramer-binding CDS’ T lymphocytes were demonstrable not only in the peripheral blood, but in lymph nodes and even in semen of chronically SIV-infected monkeys. The central role of these effector T lymphocytes in containing SIV spread during primary infection was demonstrated by showing that early SIV clearance during primary infection correlated with the emergence of the tetramer binding CD8+ T lymphocytes and that in vivo depletion of CD8+ lymphocytes eliminated the ability of the infected monkeys to contain SIV replication. These observations suggest that an effective AIDS vaccine should elicit a potent virus-specific CTL response. In fact, a live, recombinant SIV vaccine constructed using the attenuated pox virus vector modified vaccinia Ankara (MVA) elicited a high-frequency CTL response, comparable in magnitude to that elicited by SIV infection itself This suggests that vaccine modalities such as MVA may prove useful in creating an effective human immunodeficiency virus (HIV) vaccine, These studies also indicate the power of both the SIV/macaque model and MHC class I/peptide tetramers for assessing AIDS vaccine strategies.
    Type of Medium: Electronic Resource
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