ISSN:
1420-908X
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Clinical observations have shown histamine-typical cardiopulmonary reactions immediately after application of heparin. Heparin is produced from animal tissues, rich in mast cells which contain both heparin and histamine. Heparin in clinical use might therefore still contain considerable amounts of histamine. After mixing heparin with human blood,in vitro, an increase in plasma histamine concentration was observed. Additionally, histamine, in various concentrations, could be detected in different heparin batches and separations.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01997328
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