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  • 1
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Carbon nitride films were successfully prepared by ion beam synthesis method. 100 keV N+ ions at a dosage of 1.2×1018 cm−2 were implanted into carbon thin films at different temperatures. The samples were evaluated by x-ray photoelectron spectroscopy (XPS), Raman spectroscopy, cross-sectional transmission electron microscopy (XTEM), Rutherford backscattering spectroscopy (RBS), x-ray diffraction analysis (XRD), and Vickers microhardness measurement. XPS results show that most of the implanted nitrogen atoms are free state. Most of the carbon atoms have C–C bonding and a little of them form a C–N bond. It also can be clearly seen that the content of the C–N covalent bonding state in the samples is increased by raising the implanting temperature of the samples. Raman spectrum indicates that there is a Raman band near 2300 cm−1 corresponding to carbon-nitrogen stretching. XTEM and RBS studies show that there is a buried layer of carbon nitride. XRD and TEM analyses reveal that the buried carbon nitride is predominantly amorphous with a small volume fraction of nanocrystallites. The sample has a higher hardness than that of a carbon thin film. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 66 (1995), S. 3290-3291 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Our preliminary studies show that covalent solid CNx compounds can be synthesized by high dose nitrogen implantation into carbon thin films. 100 keV N+ ions at a dosage of 1.2×1018 cm−2 were implanted at different temperatures. The samples were evaluated by x-ray photoelectron spectroscopy (XPS), x-ray diffraction analysis, and Fourier transform infrared absorption spectroscopy (FTIR). N(1s) core level line XPS analyses show the existence of two different N(1s) bonding states, corresponding to the nitrogen of the C–N covalent bonding state and free state nitrogen, respectively. More importantly, it can be clearly seen that the content of C–N covalent bonding state in the samples is increased with increasing of the implanting temperature of samples. When implantation was performed at 500 °C, C(1s) XPS studies show the existence of three different C(1s) bonding states, corresponding to graphite, i-carbon, and the carbon of C–N covalent bonding state, respectively, and FTIR analyses indicate that there is an absorption band near 2200 cm−1 assigned to the C≡N covalent bonding. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 117 (1995), S. 4367-4373 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Alterations of oxidative phosphorylation in tumour cells were originally believed to have a causative role in cancerous growth. More recently, mitochondria have again received attention with regards to neoplasia, largely because of their role in apoptosis and other aspects of tumour biology. The ...
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1423-0127
    Keywords: Morphine ; Butorphanol ; Dependence, physical ; Glutamate ; Locus coeruleus ; Microdialysis ; Protein kinases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract To investigate the role of glutamate in the locus coeruleus (LC) during opioid withdrawal, rats were continuously infused with morphine (a μ-opioid receptor agonist, 26 nmol/µl/h) or butorphanol (a μ/δ/κ-mixed opioid receptor agonist, 26 nmol/µl/h) intracerebroventricularly (i.c.v.) via osmotic minipumps for 3 days. A direct LC injection of glutamate (1 or 10 nmol/5 µl) or naloxone (an opioid receptor antagonist, 24 nmol/5 µl) induced withdrawal signs in morphine- or butorphanol-dependent animals. However, these agents failed to precipitate any withdrawal signs in saline-treated control animals. On the other hand, the expression of withdrawal signs precipitated by the administration of glutamate or naloxone in opioid-dependent animals was completely blocked by concomitant infusion with 1 or 10 nmol/µl/h of an inhibitor of adenosine 3′,5′-cyclic monophosphate (cAMP)-dependent protein kinase and protein kinase C, H-7 [1-(5-isoquinolinesulfonyl)-2-methylpiperazine]. In animals that had been infused with opioids in the same manner, i.c.v. injection of naloxone (48 nmol/5 µl) precipitated withdrawal signs and increased extracellular fluid levels of glutamate in the LC of morphine- or butorphanol-dependent rats measured by in vivo microdialysis method. However, concomitant infusion with H-7 inhibited the increases of glutamate levels in the LC. These results strongly suggest that an expeditious release of glutamate in the LC region plays an important role in the expression of physical dependence on opioids. Furthermore, the action on glutamate release might be increased by the enhancement of cAMP-dependent protein kinase and/or protein kinase C activity.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of paleolimnology 14 (1995), S. 337-354 
    ISSN: 1573-0417
    Keywords: pollen ; palaeoecology ; paleoclimate ; glacial ; interglacial ; DCA ; North America
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences
    Notes: Abstract Raymond Basin and Bald Knob Basin, Montgomery County, Illinois, formed as kettles during Illinoian time. Fossil pollen from these basins provides information on vegetation and climate during the last glacial-interglacial cycle. The pollen profile at Raymond Basin contains an expanded Sangamonian section and an early Wisconsinan section, but both are missing the late Wisconsinan. The ages for the following pollen zones are estimated by correlation with the deep-sea δ18O record. In the late Illinoian,Picea-Pinus pollen zone 1, dating from about 150–130 ka, represents an apparently closed boreal coniferous forest indicating a cold late-glacial climate. The Sangamonian includes three major pollen zones ranging from about 130–75 ka. The early Sangamonian is represented byQuercus-Ulmus-Carya-Fagus dominance in zone 2, indicating vegetation comparable to the modern deciduous forest and climate that was warm and moist. The middle Sangamonian in zone 3, which is characterized byAmbrosia-Poaceae-Cupressaceae-Quercus pollen, suggests a savanna vegetation and a warm, dry climate. The late Sangamonian is subdivided into aQuercus-Ulmus-Carya subzone (4a) that indicates a mesic forest and greater precipitation; aQuercus-Ambrosia subzone (4b) that suggests drier climate and savanna conditions; and aQuercus-Liquidambar-Carya subzone (4c), containing the ‘southeastern forest’ element,Liquidambar, suggesting the peak in warmth and moisture. The early Wisconsinan is represented by a transitionalPicea-Chenopodiineae zone (5). This unusual assemblage suggests a cool prairie-like vegetation, perhaps with scatteredPicea trees at the end of that depositional interval. The Middle Wisconsinan is marked by the return of high percentages ofPicea andPinus pollen in zone 6. The latest pollen zone (7) is dominated by Chenopodiineae pollen and is absent at Raymond Basin. It is most likely Holocene in age, and probably represents prairie conditions and warm, dry climate. Apparent surface-temperature and apparent effective-moisture curves were derived from the first detrended correspondence analysis (DCA) axis of the pollen data. The first axis correlates well with the normalized deep-sea δ18O curve of sea surface temperature, and the second is controlled mainly by precipitation. The interglacial vegetation differs from that predicted by models driven by orbitally-induced insolation curves.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Somatic cell and molecular genetics 24 (1998), S. 363-369 
    ISSN: 1572-9931
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Tc1/mariner transposons are widespread in the eukaryotes. In vitro transposition test indicated that the transposase is the only protein that is needed in transpositions. It was shown later that the reconstructed Tc1-like transposon, “sleeping beauty” in fish, and the Tc1 transposon in C. elegans jumps in human cells. This discovery indicates that the Tc1/mariner transposon may be engineered as a somatic gene therapy vector if coupled with an efficient gene delivery system. We introduced the Tc1 transposon from C. elegans into different mammalian cell lines and detected the transposition events, indicating that Tc1 transposon functions in different mammalian cells. Interestingly, a high inversion frequency of the transposon was also detected, suggesting that this type of transposon may add variations to host genome when it is horizontally transferred into a new species.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1573-501X
    Keywords: Solid support synthesis ; Benzamides ; Sulfonamides ; Ureas
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary A series of analogous arrays of small, non-peptidyl, non-oligomeric compounds were synthesized on polystyrene resin. With the aid of a functionally differentiated phenolic scaffold, the batch preparation of unique benzamide and urea resins was accomplished, which were further derivatized in modified 96-well plates. An efficient cleavage reaction of the phenyl benzoate link enabled the isolation of more than 600 phenolic compounds in milligram quantities that were suitable for direct biological screening. The technology described herein represents a facile, economical approach to non-peptidyl chemical diversity.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Polymers for Advanced Technologies 7 (1996), S. 701-703 
    ISSN: 1042-7147
    Keywords: bifunctional catalyst composition ; propylene carbonate ; dialkyl carbonate ; carbon dioxide ; poly(ethylene glycol) ; alcohols ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Poly(ethylene glycol)-potassium iodide complexes were found to have high catalytic activities in the esterification of propylene oxide and carbon dioxide under smooth experimental conditions. Furthermore, the complexes were combined with sodium methoxide to form bifunctional catalyst compositions sequentially for the above esterification, as well as the transesterification of the propylene carbonate formed in situ with some aliphatic alcohols, such as methanol, ethanol, propanol and butanol. It was found that the compositions were very effective, giving corresponding dialkyl carbonate, propylene carbonate and propylene glycol. It was noticed that the resulting dialkyl carbonate from n-butanol was diisobutyl carbonate, instead of di-n-butyl carbonate.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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