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  • 1
    Digitale Medien
    Digitale Medien
    Amylin tonally regulates arginine-stimulated insulin secretion in rats (1994)
    Springer
    Diabetologia 37 (1994), S. 436-438 
    Details
    ISSN: 1432-0428
    Schlagwort(e): Key words Amylin physiology, insulin secretion, amylin antagonists, islet paracrine physiology.
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary To assess the effect of naturally-present amylin in the control of insulin release we infused a novel amylin antagonist, its 8–37 fragment, or amylin in anaesthetized rats for 60 min, and 30 min after the start arginine was infused for 14 min. Amylin8–37 decreased the blood glucose concentration by 18 % whereas the plasma insulin concentration was 90 % higher following arginine treatment. In contrast amylin infusion raised both glucose and insulin concentrations. These results suggest that while amylin added at high dose can induce peripheral insulin resistance, naturally present amylin tonally controls insulin secretion. [Diabetologia (1994) 37: 436–438]
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00408483
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Artikel (Nationallizenzen)
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  • 2
    Digitale Medien
    Digitale Medien
    Amylin tonally regulates arginine-stimulated insulin secretion in rats (1994)
    Springer
    Diabetologia 37 (1994), S. 436-438 
    Details
    ISSN: 1432-0428
    Schlagwort(e): Amylin physiology ; insulin secretion ; amylin antagonists ; islet paracrine physiology
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary To assess the effect of naturally-present amylin in the control of insulin release we infused a novel amylin antagonist, its 8–37 fragment, or amylin in anaesthetized rats for 60 min, and 30 min after the start arginine was infused for 14 min. Amylin8–37 decreased the blood glucose concentration by 18 % whereas the plasma insulin concentration was 90 % higher following arginine treatment. In contrast amylin infusion raised both glucose and insulin concentrations. These results suggest that while amylin added at high dose can induce peripheral insulin resistance, naturally present amylin tonally controls insulin secretion.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00408483
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
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