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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 591 (1990), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2072
    Keywords: Peripheral benzodiazepine receptor ; Central benzodiazepine receptor ; Ligands ; Passive avoidance ; Shuttlebox escape ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Previous research has demonstrated that low doses of anxiogenic central benzodiazepine receptor (CBR) ligands, the beta-carbolines, improve performance in various learning and memory tests in animals if administered prior to training. The present experiments compared the effect of a beta-carboline (FG 7142) with that of a pharmacologically distinct anxiogenic compound, a peripheral benzodiazepine receptor (PBR) ligand, 4′-chlorodiazepam (Ro5-4864), in two tests of learning and memory in rats. As expected, FG 7142 significantly improved performance in a passive avoidance test. Ro5-4864 was without effect. In a shuttlebox escape test, Ro5-4864 significantly impaired performance while FG 7142 had no effect. The effect of Ro5-4864 was antagonized by the specific peripheral benzodiazepine receptor antagonist, PK 11195. These results indicate that the differential impact of CBR and PBR anxiogenic ligands on performance in aversively-motivated learning tests may be a reflection of their distinct pharmacologies.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and computational fluid dynamics 4 (1993), S. 255-269 
    ISSN: 1432-2250
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract In this paper we establish some rigorous connections between the dynamics of coherent structures in the wall region of the turbulent boundary layer and the low-dimensional models of the type studied by Aubry et al. (1988). An important first step is to determine what sort of connection is feasible. We choose to study the energy budget of the models in comparison with the energy budget of the real flow. This is done by comparing the respective kinetic energy equations. In the process we reexamine some of the assumptions and approximations of Aubry et al. (1988) and perform order of magnitude analyses to determine when they hold. We find that, for the models developed in that paper, involving modes which do not vary in the streamwise direction, the energy production lies within positive, experimentally determined, bounds. Moreover, the dissipation due to neglected modes may be reproduced correctly with an order 1 value of the Heisenberg parameter α, as assumed by Aubry et al.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Archive for rational mechanics and analysis 121 (1992), S. 37-85 
    ISSN: 1432-0673
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Abstract We investigate the behavior of a continuum model designed to provide insight into the dynamical development of microstructures observed during displacive phase transformations in certain materials. The model is presented within the framework of nonlinear viscoelasticity and is also of interest as an example of a strongly dissipative infinite-dimensional dynamical system whose forward orbits need not lie on a finite-dimensional attracting set, and which can display a subtle dependence on initial conditions quite different from that of classical finite-dimensional “chaos”. We study the problem of dynamical (two-dimensional) anti-plane shear with linear viscoelastic damping. Within the framework of nonlinear hyperelasticity, we consider both isotropic and anisotropic constitutive laws which can allow different phases and we characterize their ability to deliver minimizers and minimizing sequences of the stored elastic energy (Theorem 2.3). Using a transformation due to Rybka, we recast the problem as a semilinear degenerate parabolic system, thereby allowing the application of semigroup theory to establish existence, uniqueness and regularity of solutions in L p spaces (Theorem 3.1). We also discuss the issues of energy minimization and propagation of strain discontinuities. We comment on the difficulties encountered in trying to exploit the geometrical properties of specific constitutive laws. In particular, we are unable to obtain analogues of the absence of minimizers and of the non-propagation of strain discontinuities found by Ball, Holmes, James, Pego & Swart [1991] for a one-dimensional model problem. Several numerical experiments are presented, which prompt the following conclusions. It appears that the absence of an absolute minimizer may prevent energy minimization, thereby providing a dynamical mechanism to limit the fineness of observed microstructure, as has been proved in the one-dimensional case. Similarly, viscoelastic damping appears to prevent the propagation of strain discontinuities. During the extremely slow development of fine structure, solutions are observed to display local refinement in an effort to overcome incompatibility with boundary and initial conditions, with the distribution and shape of the resulting finer scales displaying a subtle dependence on initial conditions.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1573-1987
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract We present brief précis of three related investigations. Fuller accounts can be found elsewhere. The investigations bear on the identification and prediction of coherent structures in turbulent shear flows. A second unifying thread is the Proper Orthogonal Decomposition (POD), or Karhunen-Loève expansion, which appears in all three investigations described. The first investigation demonstrates a close connection between the coherent structures obtained using linear stochastic estimation, and those obtained from the POD. Linear stochastic estimation is often used for the identification of coherent structures. The second investigation explores the use (in homogeneous directions) of wavelets instead of Fourier modes, in the construction of dynamical models; the particular problem considered here is the Kuramoto-Sivashinsky equation. The POD eigenfunctions, of course, reduce to Fourier modes in homogeneous situations, and either can be shown to converge optimally fast; we address the question of how rapidly (by comparison) a wavelet representation converges, and how the wavelet-wavelet interactions can be handled to construct a simple model. The third investigation deals with the prediction of POD eigenfunctions in a turbulent shear flow. We show that energy-method stability theory, combined with an anisotropic eddy viscosity, and erosion of the mean velocity profile by the growing eigenfunctions, produces eigenfunctions very close to those of the POD, and the same eigenvalue spectrum at low wavenumbers.
    Type of Medium: Electronic Resource
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