ISSN:
1573-6830
Keywords:
excitable membrane
;
ionic channel
;
heavy metal
;
metal ion-induced current
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary 1. The paper summarizes the effects of the metal ions Cu2+, Pb2+, Ag+, Hg2+, Zn2+, and Cd2+ applied externally or internally to the surface membrane of different excitable cells. 2. Conductance changes induced by metal ions, and metal ion-activated current, are compared with respect to their ion and voltage dependence. 3. It is suggested that metal ion-induced effects can be realized through special structures of the cell membrane, the metal ion “receptors,” although other mechanisms, as, for example, competition for Ca-binding sites in the channel forming proteins, cannot be excluded.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02088684
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