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  • 1
    Electronic Resource
    Electronic Resource
    Neonatal intestinal perforation in Hirschsprung's disease (1994)
    Springer
    Pediatric surgery international 9 (1994), S. 501-502 
    Details
    ISSN: 1437-9813
    Keywords: Hirschsprung's disease ; Intestinal perforation ; Neonate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Over a period of 18 years, 77 of 135 patients treated for Hirschsprung's disease (HD) presented in the neonatal period. Of these 77 patients, 8 had gastrointestinal (GI) perforations. Seven patients were born at full term and 1 at 32 weeks of gestation. Three patients had associated trisomy 21. The site of perforation included rectum in 1 patient, sigmoid in 1, descending colon in 1, transverse colon in 2, caecum in 2, and jejunum in 1. Perforations occurred in ganglionic bowel in 7 patients and in the aganglionic segment in 1. One patient died in the newborn period of overwhelming sepsis secondary to enterocolitis, and histology of the bowel confirmed HD. In 6 patients HD was confirmed on barium enema and suction rectal biopsy, and they subsequently underwent a definitive pull-through operation. The 1 patient in whom the initial barium enema was normal continued to suffer from constipation until the age of 7 years, when the diagnosis of HD was established. He then underwent a pull-through procedure with no further problems. An association between neonatal intestinal perforation and HD must therefore be recognised to avoid delay in the management.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00179451
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  • 2
    Electronic Resource
    Electronic Resource
    Evaluation of risk factors in the development of enterocolitis complicating Hirschsprung's disease (1994)
    Springer
    Pediatric surgery international 9 (1994), S. 234-236 
    Details
    ISSN: 1437-9813
    Keywords: Hirschsprung's disease ; Enterocolitis ; Child
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Enterocolitis remains a major cause of morbidity and mortality in patients with Hirschsprung's disease (HD). Forty-one (30%) of 135 patients treated for HD from 1975 to 1992 developed enterocolitis; enterocolitis occured preoperatively in 25. It was a presenting feature in 17 infants, including 11 neonates. The proportion of patients presenting with enterocolitis in the neonatal period increased with advancing age, 6 (11%) out of 56 presenting within the 1st week and 5 (24%) out of 21 after 1 week. Episodes of enterocolitis continued in 7 of these 25 patients after a pull-through procedure. Sixteen patients had a first episode of enterocolitis after surgery: 3 after a colostomy, and 13 after a pull-through procedure. The incidence of enterocolitis was 28% in patients with rectosigmoid involvement and 38% in patients with long-segment or total colonic aganglionosis (P= 0.1). Enterocolitis occured in 8 (47%) of 17 patients with trisomy 21 as compared to 33 of 118 (28%) other patients (P= 0.1). Four of the 41 patients died as a result of enterocolitis, 3 in the neonatal period after a colostomy performed at a mean age of 22 days, although the symptoms suggestive of HD were present since birth. Prompt diagnosis and expeditious management are necessary in patients with HD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00832245
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  • 3
    Electronic Resource
    Electronic Resource
    Intercellular adhesion molecule-1 (ICAM-1) in the pathogenesis of enterocolitis complicating Hirschsprung's disease (1994)
    Springer
    Pediatric surgery international 9 (1994), S. 237-241 
    Details
    ISSN: 1437-9813
    Keywords: Hirschsprung's disease ; Enterocolitis ; Intercellular adhesion molecule-1 (ICAM-1)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Intercellular adhesion molecule-1 (ICAM-1) is a glycoprotein that is necessary for the transendothelial migration of leucocytes. This study was undertaken to elucidate the role of ICAM-1 in the pathophysiology of Hirschsprung's disease (HD)-related enterocolitis. Ganglionic and aganglionic portions of bowel from 18 patients with HD who did not have clinical or histological evidence of enterocolitis and 5 patients with HD who developed enterocolitis before or after a pull-through operation were stained using monoclonal antibody against ICAM-1. The bowel specimens obtained from 2 children with imperforate anus at the time of colostomy closure and 3 children at the time of bladder augmentation were similarly stained to act as controls. The ganglionic portion of bowel from patients with HD without enterocolitis and controls showed either no ICAM-I staining or occasional staining of the endothelial lining of submucosal vessels with no staining of the glandular crypt epithelium. In contrast, both ganglionic and aganglionic bowel from patients with enterocolitis complicating HD demonstrated strong ICAM-1 staining in the endothelium of submucosal vessels. Strong expression of ICAM-1 in the glandular crypt epithelium was seen in only 2 patients who had developed enterocolitis before pull-through operations. This study illustrates the importance of endothelial cell activation in the pathogenesis of HD-related enterocolitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00832246
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  • 4
    Electronic Resource
    Electronic Resource
    Hirschsprung's disease in association with trisomy 21 and duodenal obstruction (1994)
    Springer
    Pediatric surgery international 9 (1994), S. 366-367 
    Details
    ISSN: 1437-9813
    Keywords: Hirschsprung's disease ; Trisomy 21 ; Duodenal obstruction ; Child
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The association of trisomy 21 and Hirschsprung's disease (HD) is well known. In a neonate, HD characteristically presents with delayed passage of meconium and/or intestinal obstruction. However, the presence of duodenal atreasia (DA), which may present similarly, can mask the associated HD. Over an 18-year period, 17 of 135 patients with HD had trisomy 21. Three of these 17 patients presented with duodenal obstruction in the newborn period — 2 had DA and 1 a complete duodenal web. One patient developed a perforation of the jejunum 7 days after laparotomy and duodenoduodenostomy and was found to have HD while the other 2 were later investigated because of persistent unresponsive constipation and confirmed to have HD at 1 and 2 years of age. In spite of associated Down's syndrome and DA, the possibility of HD should be considered in patients who have a complicated postoperative course or persisting abnormal stooling patterns.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01686003
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  • 5
    Electronic Resource
    Electronic Resource
    Unsteady magnetohydrodynamic flows in a rotating elastico-viscous fluid (1994)
    Springer
    Astrophysics and space science 219 (1994), S. 257-264 
    Details
    ISSN: 1572-946X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract This paper points out the errors in the solutions of a research work by N. Nanousis under the same title published in this journal, volume 199, 1993. The correct solutions of the problem for the velocity field and the drag on the plate, by the Laplace transform technique, are presented. The results are discussed for two cases of an arbitrary time-dependent forcing effect. It is shown that the viscoelastic parameterk 〉 0 influences the velocity and introduces reverse flow. For a suddenly accelerated plate,k 〉 0 increases the velocity forz 〈 $$\sqrt {2t} $$ and decreases it forz 〉 $$\sqrt {2t} $$ . In the case of the ramp-type boundary condition,k 〉 0 tends to decrease the velocity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00628242
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  • 6
    Electronic Resource
    Electronic Resource
    The effects of induced magnetic field on unsteady hydromagnetic flows in a rotating medium (1990)
    Springer
    Astrophysics and space science 174 (1990), S. 121-133 
    Details
    ISSN: 1572-946X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Unsteady flows of a viscous incompressible electrically conducting fluid filling the semi-infinite space in contact with an infinite conducting plate in a rotating medium in the presence of a transverse induced magnetic field are investigated under an arbitrary time-dependent forcing effect on the motion of the plate where the plate and the fluid rotate uniformly as a rigid body. By using the Laplace transform technique, the Greens function of the problem is determined and certain asymptotic expansions of the exact solutions are analyzed. the steady-state oscillatory flow problem is solved, and structure of waves and displacement thickness of the boundary layers are discussed for different cases of some natural parameters in the problem. The results are compared with similar flows in the presence of a constant magnetic field.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00645658
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  • 7
    Electronic Resource
    Electronic Resource
    Pairwise-balanced, variance-balanced and resistant incomplete block designs revisited (1990)
    Springer
    Annals of the Institute of Statistical Mathematics 42 (1990), S. 163-171 
    Details
    ISSN: 1572-9052
    Keywords: Block design ; pairwise balance ; variance balance ; resistance ; BIB design
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract A general solution is derived to the problem of characterizing block designs that are simultaneously pairwise-balanced and variance-balanced. Applications of the characterizations obtained to some problems concerned with the local resistance of BIB designs are presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00050787
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