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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 650 (1992), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 69 (1991), S. 1648-1653 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The upconversion of infrared radiation to shorter wavelengths by Er3+ ions in heavy-metal fluoride glasses, some doped with Yb3+, has been studied over a wide intensity range and for various excitation wavelengths. The upconversion efficiency measured at room temperature varies linearly or quadratically with intensity and saturates at 100 W/cm2 or higher, depending on emission wavelength. For 4 mol % ErF3 in BaF2/ThF4, the 4I11/2 to 4I15/2 transition is over 10% efficient for 400 W/cm2 of absorbed 1.5-μm power, i.e., for 4I15/2 to 4I13/2 excitation. A rate equation model and Judd–Ofelt analysis of data for the glasses doped with just Er3+ provide an understanding of the upconversion process while yielding values for Er3+ energy-transfer rates and excited-state populations. These results could be used to develop glasses for lasing and as infrared optical detectors.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 49 (1993), S. 2091-2093 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 249 (1992), S. 325-328 
    ISSN: 1434-4726
    Keywords: Auditory maturation ; Binaural interaction components ; Auditory brainstem responses ; Conductive hearing loss ; Guinea pigs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Reversible conductive hearing loss created during the first 4 weeks post partum caused marked alterations in the maturation of binaural interaction components in the auditory brainstem responses of guinea pigs. In untreated control animals all three components investigated demonstrated postnatal development in terms of latency shortening that was completed during the first 3 weeks of life. Plugging of both external ear canals caused a significant delay in the maturation of the late component DN2, where latency values of the controls were reached only 2 weeks after the end of the treatment, i.e. after 6 weeks of life. Monaural deprivation likewise led to a retarded development of peak latencies during the phase of imbalanced sensory imput. After the end of the one-sided conductive hearing loss the maturation process was markedly enhanced, even resulting in latency values for DN2 and DP1 that were significantly shorter than those of the controls. This phenomenon persisted until the end of the study period and was the case for both plugged and untreated ears in this group of animals. The time course of latencies in two other groups of experimental animals which were deprived in the same way as adults suggests that the effects observed are due to a sensitive period in the maturation process of the auditory pathway.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 251 (1994), S. 36-40 
    ISSN: 1434-4726
    Keywords: Facial muscle ; Enzyme histochemistry ; Facial palsy ; Experimental denervation ; Reinnervation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The morphological changes in rat facial muscles were evaluated after permanent denervation and were compared with findings after immediate reinnervation. Thirty rats underwent transection of the left and right facial nerves immediately followed by hypoglossal-facial nerve anastomosis on the right side (muscular reinnervation) and removal of 8–10 mm of the facial plexus on the left side (permanent muscular denervation). Levator labii muscle samples of both sides were collected sequentially at 2, 6, 7, 10, 20, and 24 weeks after surgery and submitted to routine histological and enzyme histochemical staining procedures. In normal levator labii muscles a typical “chessboard” pattern was found, with type I fibers being smaller than type II fibers. These latter fibers also were more prevalent than the type I fibers. Among the type II fiber subtypes, the type IIB fibers were larger and more frequent. Two weeks after surgery, there were no differences between denervated facial muscles and those undergoing reinnervation. Both showed atrophic myofibers among normal-sized fibers and slight fibrosis. Those muscles denervated for more than 2 weeks displayed increasing fiber atrophy with frequent loss of typability, as well as proliferation of connective tissue and fat cells in perimysial and endomysial sites. After denervation for 20 weeks only a few atrophic fibers were found in wide areas of fibrosis and fat cells. Following nerve anastomosis the reinnervated levator labii muscle showed much less fiber atrophy. Regrowth to normal fiber diameters was found with only a few atrophic myofibers 10 weeks after anastomosis although a moderate fibrosis predominated at perimysial sites. Reinnervated facial muscle fibers displayed a typical type-grouping pattern and also frequent lack of typability.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    International journal of colorectal disease 7 (1992), S. 192-196 
    ISSN: 1432-1262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Entre 1985 et 1992 46 patients avec un cancer épidermoide du canal anal ont été traités prospectivement par un protocole d'irradiation combiné à une chimiothérapie par 5-Fluorouracil et Mitomycin C. Le taux de survie, le taux de survie NED et le taux de contrôle local des tumeurs était de 84%, 71% et 83% à 5 ans. La fonction ano-rectale a été préservée chez 33 des 41 patients (80%). Nous avons observé une toxicité aigue sévère comprenant 3 décés mais une très faible morbidité ultérieure. Le seul facteur pronostic significatif (P=0.06) de contrôle local de la tumeur était le stade T. La survie NED était significativement affectée (P=0.02) par la réduction de la chimiothérapie durant la deuxième cure.
    Notes: Abstract Between 1985 and 1992, 46 patients with epidermoid carcinoma of the anal canal were treated prospectively by a protocol of combined radiation and chemotherapy with 5-Fluorouracil and Mitomycin C. The survival rate, NED-survival rate and local tumour control rate were 84%, 71% and 83% at 5 years. Anorectal function was retained in 33 of 41 patients (80%). We observed severe acute toxicity including three deaths, but very little late morbidity. The only marginally significant prognostic factor (P=0.06) for local tumour control was T-stage. NED-survival was significantly affected (P=0.02) by reduction of chemotherapy during the second course.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    International journal of colorectal disease 9 (1994), S. 200-202 
    ISSN: 1432-1262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Six femmes et 39 hommes ont été traités entre janvier 1985 et décembre 1988 d'un sinus pilonidal non enflammé au moyen de sclérothérapie. En anesthésie locale, 1 à 2 ml d'une solution à 80% de phénol sont injectés dans le sinus. Le phénol est laissé en place durant 1 minute puis le sinus est irrigué avec une solution physiologique habituelle. Un questionnaire a été envoyé à 45 patients; 37 questionnaires sont utilisables pour l'évaluation. Une guérison compléte survient chez 22 patients (59,5%). Le temps de guérison moyen est de 6,2 semaines. En dehors d'une rougeur transitoire observée fréquemment en réponse á une inflammation causée par le phénol, 5 patients ont développé un abcès nécessitant un traitement chirurgical. Cette étude ne confirme donc pas les résultats encourageants d'autres séries.
    Notes: Abstract Six female and 39 male outpatients, who suffered from acutely inflamed pilonidal sinus were treated by sclerotherapy between January 1985 and December 1988. Under local anaesthesia, 1–2 ml 80% phenol was injected into the sinus. The phenol, which was allowed to act for a minute, was washed out by irrigating the sinus with physiological common-salt solution. Of the questionnaire sent to all 45 patients, 37 proved suitable for evaluation. Complete healing occurred in 22 cases (59,8%). The healing time was 6.2 weeks on average. Besides a rather frequently observed transient reddening as a result of the local inflammation caused by the phenol, 5 patients developed an abcess which needed operative treatment. This study does not support the encouraging results of previous series.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 250 (1993), S. 362-365 
    ISSN: 1434-4726
    Keywords: Auditory maturation ; Conductive hearing loss ; Auditory brainstem responses ; Middle latency responses ; Guinea pigs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A reversible conductive hearing loss produced during the first 4 weeks post partum caused marked alterations in the development of click-evoked auditory brainstem (ABR) and middle latency (MLR) responses in guinea pigs. The early component PI in the ABR in controls showed adult-like latencies at the time of birth, while the later ABR components PIII and PV and all components investigated in the MLR showed postnatal development characterized by a shortened latency that persisted for the whole period of investigation. The course of the ABR latencies showed the sharpest decrease during the first 2–3 weeks of life, while that for the MLR took place during the first 5 weeks. In addition to the increased ABR thresholds and lengthened ABR latencies due to the conductive hearing loss, development of the ABR inter-peak latencies (IPL) and MLR latencies was retarded. The IPL reached control values 1 week after the end of the deprivation phase, while the delay in MLR started later (4th week) and lasted longer than did that in the ABR. These findings showed that a long-lasting postnatal conductive hearing loss does not generate sustained impairment at the level of the brainstem but can evoke longer-lasting deficiencies at higher stations of the auditory pathway.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 379 (1994), S. 188-192 
    ISSN: 1435-2451
    Keywords: Laparoscopic colorectal surgery ; Valtrac ring ; Laparoscopic purse-string suture clamp
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Eine neu entwickelte laparoskopische Tabaksbeutelnahtklemme bietet in Kombination mit dem biofragmentierbaren Valtrac®-Ring die Möglichkeit, Anastomosen im Dünn- und Dickdarm intrakorporal ohne Stapler zu erstellen. Im Rahmen der hier vorgestellten tierexperimentellen Studie wurde bei 5 Schweinen eine End-zu-End-Anastomose im Colon descendens gebildet. Die Nachuntersuchung erfolgte bei 4 Tieren nach 21 Tagen und bei einem Tier am 1. postoperativen Tag. Eine Anastomoseninsuffizienz war in keinem Fall festzustellen. Die Anastomosen der Tiere, die 3 Wochen postoperativ nachuntersucht wurden, wiesen sowohl makroskopisch als auch histologisch nur geringe Narbenbildung auf. Die hier vorgestellte Anastomosentechnik könnte in Zukunft eine Alternative zu den assistiert laparoskopischen Eingriffen am rechten Kolon darstellen.
    Notes: Abstract In combination with the biofragmentable Valtrac ring a newly developed purse-string suture clamp offers the possibility of performing intraperitoneal anastomoses of the small and large bowel without the need for stapling devices. During this experimental study endto-end anastomoses of the descending colon were constructed in five pigs. One animal was re-examined on day 1 after the operation and the others were all sacrificed on day 21 after. None of the animals showed any signs of an anastomotic leakage. Little scar tissue was seen macroscopically or histologically in the anastomotic region of the animals sacrificed 3 weeks after the operation. The operative technique presented in this paper might render the so-called assisted laparoscopic procedures for the right hemicolon unnecessary in the future.
    Type of Medium: Electronic Resource
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