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  • 1990-1994  (5)
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  • 1
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: We evaluated the haemocompatibility of a filter of poly(butylene terephthalate) for packed red cell transfusions, which had undergone a physicochemical treatment (corona treatment) in order to reduce the filling time. Leucocyte, erythrocyte and platelet counts were carried out and haematological and coagulation parameters were examined before and after filtration. Moreover, some biochemical plasma parameters were evaluated, which are normally checked in hospitalized patients. The results obtained show that the filter treatment reduces the filling time, does not reduce the efficiency in retaining leucocytes and platelets,and does not induce alterations in filtered red blood cells. However, the treatment prolongs the activated partial thromboplastin time (APTT) and reduces the activity of some factors of the intrinsic coagulation pathway. On the other hand, it does not induce modifications in the biochemical parameters examined.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: This study was focused on the bone tissue response to cement in failed hip joint prostheses. The investigation was carried out by means of micro-beam X-ray diffractometric (XRD) analysis of the bone-cement interface. Nine cemented prostheses retrieved because of loosening were studied. This research has demonstrated that the newly formed bone close to the cement in loosened prostheses showed a normal apatitic structure, though bone tissue was often found poorly mineralized. In contrast, in stable prostheses well-mineralized bone was observed. In both cases, however, the bone apatite lattice at the interface was shown not to be different from pre-existing bone. The authors conclude that the mineralization process close to the cement can be thoroughly evaluated by micro-beam XRD techniques.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Polymeric materials are of widespread use for many clinical applications, including dentistry. Periodontal guided tissue regeneration (GTR) is a technique developed to treat periodontal disease: it implies that new connective tissue attachment and bone regeneration are achieved, whereas epithelial migration is prevented by the placement of a barrier membrane. This study has focused on the toxicity in vitro of different polymeric membranes, either commercial or experimental, with a latex rubber membrane being of special interest for use as an implant material in guided tissue regeneration in periodontology. A cell culture system tested by quantitative assay methods offered a reliable tool which provided meaningful results on the first level biocompatibility of such membranes.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 3 (1992), S. 252-254 
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract Small cylinders of a new composite porous material consisting of a dense alumina core coated with two layers of beads of the same material, bonded to each other and to the underlying surface by a high-temperature melting glass have been implanted in the proximal femurs of rabbits. The explants were carried out 1, 4, 6, 8, and 18 weeks after surgery. The bone fragment containing the implant was embedded in methyl methacrylate without performing decalcification, and morphological observations were carried out. These showed that four weeks after surgery it is already possible to observe the development of bone spicules in the implant porosities. Along with these studies, microhardness measurements were carried out by using a microhardness tester connected to an image analyser. The mineralized tissue in close contact with the implant showed, one month after surgery, a compression strength similar to that of healthy bone.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Currently, the use of silicone-filled devices, mainly in plastic surgery for breast reconstruction or augmentation, is being debated by the scientific community in connection with the risk to the patient. In this study the response of whole blood or isolated peripheral blood lymphocytes from patients with silicone-gel-filled breast implants was assessed in vitro, in order to verify the hypothesis of silicone material acting in vivo as a sensitizing agent. Both quantitative and qualitative changes of lymphocyte subpopulations of patients carrying silicone devices were assessed and compared with healthy subjects. Upon 24–72 h in vitro re-exposure of patients' lymphocytes to silicone extract, lymphocyte surface antigen expression was monitored by flow cytometry, and the functional response of lymphocytes was measured by radioactive tracer uptake and biochemical changes.
    Type of Medium: Electronic Resource
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