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  • 1
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 73-75 (Jan. 1991), p. 245-250 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Mineralogy and petrology 49 (1993), S. 13-25 
    ISSN: 1438-1168
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Summary Density and viscosity measurements of three melts of volcanic rock composition (basalt and andesite) at low temperatures were carried out to understand the role of free volume in the viscous behavior of a magma and to estimate the flow unit in the melts. The data combined with literature data suggest the following conclusion: free-volume theory is not applicable to these silicate melts; the relation between viscosity and the inverse of free volume does not yield a straight line in a wide temperature range from the glass-transion temperature to 1550°C. However, two depolymerized melts, diopside and Oki-Dozen alkali basalt (OAB), yield almost linear relationships. Thus, the free-volume theory should hold to a fairly good approximation for these two melts. Based on this approximation, the radius of flow unit for diopside melt was calculated to be about 4.7 Å, and that for Oki-Dozen alkali basalt to be about 4.2 Å. The three-dimensional silicate anions which may correspond to the flow unit are Si14O35 14− and Si16O40 16− for diopside melt, and Si10O25 10− and Si12O30 12− for OAB melt. The temperature effect on the initial slope of the viscosity-pressure relation has also been examined in the frame of free-volume theory. It was concluded that the relative increase of the initial slope of the relation with increasing temperature might be caused by the increase of free volume.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Contributions to mineralogy and petrology 109 (1992), S. 295-303 
    ISSN: 1432-0967
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Viscosities of diopside-anorthite melts were measured over the wide range of temperature (near the glass-transition temperature−1580°C/1bar) and pressure (5–20 kb/above the liquidus temperature). The measurements were carried out by the fibre-elongation method for low temperature and the counter-balanced sphere method for high temperature at 1 bar, and the sinking and floating spheres method for high temperature at high pressure. Some of the values obtained deviated slightly from those in the literature. The data on viscosity and the glasstransition temperature have been interpreted on the basis of the configurational entropy theory, by which temperature and compositional effects on viscosity were explained well. The configurational entropies at the glasstransition temperature of magmatic silicate melts are almost constant if we use an average molecular weight (amw) or “bead” as a unit; 8.0±1.2 J/K·amw, 1.1 ±0.2cal/K·bead. The latter value coincides well with the value from the literature for organic polymers. The negative deviation from linearity of the glass-transition temperature of intermediate melts may be interpreted as the effect of the mixing entropy. The calculated glasstransition temperature-composition curve using the mixing entropy agreed well with the experimental values.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-0428
    Keywords: Type 1 (insulin-dependent) diabetes ; streptozotocin ; interleukin 2 receptor ; anti-interleukin 2 receptor antibody ; soluble interleukin 2 receptor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Recent evidence indicates that activated T cells and macrophages play an important role in the induction of insulitis and diabetes in certain strains of mice treated with multiple subdiabetogenic doses of streptozotocin. In the present study, we treated C57BL/6J mice with five daily doses of 40 mg/ml streptozotocin and examined the prophylactic effect of an anti-interleukin 2 receptor monoclonal antibody (PC61). In mice treated with streptozotocin, interleukin 2 receptor-positive mononuclear cells were shown to infiltrate into the islets and soluble interleukin 2 receptors in the sera were significantly increased compared with control mice. The administration of PC61 to the mice attenuated the insulitis, and diminished interleukin 2 receptor-positive cells from islets and soluble interleukin 2 receptors in the sera. Moreover, the administration of PC61 significantly reduced the development of hyperglycaemia shown in these mice (12.8±1.1 mmol/l vs 18.5±0.7 mmol/l, p〈0.005). As judged by flow cytometric analysis, this antibody did not cause any changes in either spleen cell counts or T cell subsets. Interleukin 2 receptors were expressed on a minor population of spleen cells regardless of treatment with PC61 (STZ + normal rat IgG: 2.1±0.3%, STZ + PC61: 2.4±0.3%). Even after stimulation of spleen cells with concanavalin A or alloantigen, interleukin 2 receptor expression was not significantly different between the two groups. Our studies suggest that interleukin 2 receptor-positive activated T cells or macrophages are important in the development of multi-low-dose streptozotocin diabetes and that an anti-interleukin 2 receptor antibody can attenuate this process.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0584
    Keywords: Extramedullary tumor ; Malignant lymphoma ; Granulocytic sarcoma ; GPIIb- and GPIIIa-positive leukemia cell line
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A 25-year-old man noted swelling of the right cervical lymph nodes in October 1983. Diagnosis of malignant lymphoma was made on the basis of pathological examination of biopsies. Despite both chemotherapy and irradiation treatment, blast cells appeared in the peripheral blood and bone marrow in April 1984. Immunophenotypic analysis demonstrated that the blasts in the patient's peripheral blood expressed CD13, CD33, CD41a, and no markers for T or B lymphocytes, suggesting that he had been suffering from megakaryocytic sarcoma. We established a new cell line derived from the blasts in the peripheral blood, designated KH184. KH184 cells expressed glycoprotein (GP) Ib (CD42b) and GPIIb/IIIa (CD41a), while platelet peroxidase (PPO) activity was negative in an ultrastructural study. Both Northern blot and flow cytometric analysis of surface antigens and DNA content revealed that treatment with 12-O-tetradecanoylphorbol 13-acetate (TPA) did not induce the maturation of these cells. Various cytokines such as interleukin 3 (IL-3), interleukin 6 (IL-6), and leukemia inhibitory factor (LIF) had no effect in promoting the growth of KH184 cells. KH184 cells expressing CD41a seem to possess unusual characteristics. KH184 cells, human GPIIb- and GPIIIa-positive leukemia cells, which lack response to TPA-induced differentiaton, provide a new and unique model for the characterization of factors that are implicated in the terminal differentiation of megakaryocytes, and should aid in studies of the mechanism underlying the occurrence of megakaryocytic sarcoma.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1619-6937
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Summary Forced and free mixed convection boundary layer flow over a wedge with uniform suction or injection is theoretically investigated. Nonsimilar partial differential equations are transformed into ordinary differential equations by means of difference-differential method. The solutions of the resulting equations are obtained in integral forms and are calculated by iterative numerical procedures. The results were given for velocity profiles, temperature profiles, friction and heat transfer parameters for various values of suction/injection parameter, pressure gradient parameter and buoyancy parameter.
    Type of Medium: Electronic Resource
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